230035

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 1732591..1733144 Replicon chromosome
Accession NZ_CP090095
Organism Neorhizobium galegae strain 7g

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LZK81_RS08710 Protein ID WP_233955843.1
Coordinates 1732815..1733144 (+) Length 110 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LZK81_RS08705 Protein ID WP_233955842.1
Coordinates 1732591..1732815 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LZK81_RS08685 (LZK81_08685) 1728255..1728920 - 666 WP_233955841.1 protein-methionine-sulfoxide reductase heme-binding subunit MsrQ -
LZK81_RS08690 (LZK81_08690) 1728923..1729867 - 945 WP_046609134.1 protein-methionine-sulfoxide reductase catalytic subunit MsrP -
LZK81_RS08695 (LZK81_08695) 1730077..1730487 + 411 WP_046609091.1 DUF4112 domain-containing protein -
LZK81_RS08700 (LZK81_08700) 1730654..1732489 + 1836 WP_046609133.1 dihydroxy-acid dehydratase -
LZK81_RS08705 (LZK81_08705) 1732591..1732815 + 225 WP_233955842.1 DUF433 domain-containing protein Antitoxin
LZK81_RS08710 (LZK81_08710) 1732815..1733144 + 330 WP_233955843.1 DUF5615 family PIN-like protein Toxin
LZK81_RS08715 (LZK81_08715) 1733162..1733515 - 354 WP_233955845.1 hypothetical protein -
LZK81_RS08720 (LZK81_08720) 1733553..1733933 - 381 WP_233955847.1 YkvA family protein -
LZK81_RS08725 (LZK81_08725) 1734070..1735470 + 1401 WP_046624191.1 DegQ family serine endoprotease -
LZK81_RS08730 (LZK81_08730) 1735467..1736783 + 1317 WP_233955849.1 replication-associated recombination protein A -
LZK81_RS08735 (LZK81_08735) 1736801..1737115 - 315 WP_037084690.1 DUF1883 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(1-76)

Antitoxin

Protein of unknown function DUF433

(7-62)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 12363.12 Da        Isoelectric Point: 4.5849

>T230035 WP_233955843.1 NZ_CP090095:1732815-1733144 [Neorhizobium galegae]
MRFLVDAQLPPALARWLAERGHEAEHVMDCGLQSAPDREIWDFAAASGAIVVTKDEDFAQRKALLQSGPSIVWVRLPNSR
RRDLLDWFERALPDIIDALERGETLIEVI

Download         Length: 330 bp

>T230035 NZ_CP124664:3593331-3593909 [Pseudomonas aeruginosa]
ATGTCCCTCGAACTGCTGAGCAACCGCCTCGAATTCCTCCGCGAAGCCGAACGCCTGAAAGACGTCCTGCGCTCCGCGCA
CACCTCCTCCGGCCGCCCGGAAAGCACCGCCGAACATAGCTGGCGGCTGTGCCTGATGGCACTGGCCTTCGAGGACCAAC
TGGCCGGCTTGGACCTCGGCAAGGTCCTGCGCATGTGCGTGGTCCACGACCTCGGCGAAGCGATCCACGGCGACATCCCC
GCCGTCGAGCAGGCCGCGCACCCGGACAAAGGCGAACAGGAACGCGCCGACCTGTTGCAGCTGACCCGTCACCTCGACGC
GCCGCTGCGCGACCGCCTGCTCGCCCTGTGGGACGAATACGAGCGCGGCGAGTCCGCCGAAGCCCTGGCAGTGAAGGCCC
TGGACAAGCTGGAAACCCTGCTCCAGCACACCCAGGGCGACAATCCGGCGGACTTCGACTATGCCTTCAACCTCGACTAC
GGCCGTCGCTATACCGACCGCGCACCGCTGTTCAAGACCCTGCGCGAGCTACTCGACGCCAGGACCCGACAGCGCCTCGC
AGCTCGGCGCGACACCTAG

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8290.51 Da        Isoelectric Point: 5.5169

>AT230035 WP_233955842.1 NZ_CP090095:1732591-1732815 [Neorhizobium galegae]
MSELHRITFDPHICSGRPTIRGLRIRVKDVLELLASGATHEEILEDYPLLEAPDIVAALEYAARQSDHTVLRVA

Download         Length: 225 bp

>AT230035 NZ_CP124664:3592688-3593242 [Pseudomonas aeruginosa]
ATGACCGAGCCTCTCCCTTCTTCGTCCCTGGGCCCCGCCCTGCGTCGCTGGCGCCTGCTGCACCGGGTCAAGCAAACGCA
TGCCGCCGAATTGCTCGGCGTGGCGCAATCGACCATCTCGCGCTGGGAGTCCGGTACCCAGGCGCTGCTGGTGGAGGAAC
GGGCACGCCTGGAGCGTCTGCTCGGCGCCCGCCTGGAAGCCGCCGCCGACCAGGCACTGGCCCGCCTGGTCGAGGCCAAC
CCGCAACCCGTGCACCTGATCTGCGACCTCACCCATCGCCTGTTGGCCTGTTCGCCGGCACGCGCCGCGCAATTCGGCGT
GCCTCTCGGCGAACTGCTCGACCGTTCGCTGTGGCCCTATTGCAGCGAGGAAATCCTCCGCCAGGAAGCCACCCTCGAGG
AACTCGGCTGGCGCGAACTGCTGGCACCGCCGGCGCTGGAGTTCGCCAGCGGAGCGAACGCCTCGGCCATCGTGCCGATC
CGGCGCAGCCGTTGCCGCTGGACCCGCATGACCCTCTCGGACGGACGCGCGGTGCGCCTGGTGGAAACCCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References