230034

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/COG3657-dnstrm_HI1420
Location 1401710..1402308 Replicon chromosome
Accession NZ_CP090095
Organism Neorhizobium galegae strain 7g

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag LZK81_RS07000 Protein ID WP_233955628.1
Coordinates 1402006..1402308 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LZK81_RS06995 Protein ID WP_046611946.1
Coordinates 1401710..1402009 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LZK81_RS06960 (LZK81_06960) 1397211..1397831 - 621 WP_233955627.1 HD family hydrolase -
LZK81_RS06965 (LZK81_06965) 1397828..1398670 - 843 WP_046605671.1 folate-binding protein YgfZ -
LZK81_RS06970 (LZK81_06970) 1399070..1399372 - 303 WP_046605670.1 hypothetical protein -
LZK81_RS06975 (LZK81_06975) 1399661..1400401 - 741 WP_052759100.1 hypothetical protein -
LZK81_RS06980 (LZK81_06980) 1400442..1400699 - 258 WP_007752665.1 hypothetical protein -
LZK81_RS06985 (LZK81_06985) 1400801..1401229 - 429 WP_046628335.1 TIGR02301 family protein -
LZK81_RS06990 (LZK81_06990) 1401276..1401692 - 417 WP_046611947.1 NUDIX domain-containing protein -
LZK81_RS06995 (LZK81_06995) 1401710..1402009 - 300 WP_046611946.1 putative addiction module antidote protein Antitoxin
LZK81_RS07000 (LZK81_07000) 1402006..1402308 - 303 WP_233955628.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LZK81_RS07005 (LZK81_07005) 1402356..1402682 + 327 WP_233955629.1 YnfA family protein -
LZK81_RS07010 (LZK81_07010) 1402725..1403492 + 768 WP_233955630.1 SOS response-associated peptidase -
LZK81_RS07015 (LZK81_07015) 1403533..1404150 + 618 WP_233956497.1 LysE/ArgO family amino acid transporter -
LZK81_RS07020 (LZK81_07020) 1404181..1404318 - 138 WP_233955631.1 hypothetical protein -
LZK81_RS07025 (LZK81_07025) 1404493..1405335 - 843 WP_233955632.1 phosphatidylcholine/phosphatidylserine synthase -
LZK81_RS07030 (LZK81_07030) 1405353..1406051 - 699 WP_046605752.1 phosphatidylserine decarboxylase -
LZK81_RS07035 (LZK81_07035) 1406168..1407094 - 927 WP_233955633.1 AraC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Uncharacterized protein HI1420

(2-89)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11181.85 Da        Isoelectric Point: 10.0966

>T230034 WP_233955628.1 NZ_CP090095:c1402308-1402006 [Neorhizobium galegae]
MIEIQETEIYSTWFARLRDERAKARINARIYRLSLGNPGDVKPVGSGVSEMRVDYGPGFRIYFIRRGQAFVVLLCGGDKS
SQTEDIVSAKKLAAGLEGRK

Download         Length: 303 bp

>T230034 NZ_CP124664:1915375-1915962 [Pseudomonas aeruginosa]
ATGTCGAGGAGGGCGCCCATGTTCAAGCCGCTACCGATCACCCTGCAGCGCGGAGCCTTGCGTCTCGAGCCGCTGGTGGA
AGCGGACATTCCCGAGCTGGTGAGCCTCGCCGAAGCCAACCGCGAGGCGCTGCAGTACATGGACGGACCGACGCGGCCGG
ACTGGTACCGCCAGAGCCTCGCCGAGCAGCGCGAGGGCAGGGCGTTGCCGCTCGCCGTCCGCCTCGGCGTGCAACTGGTC
GGGACCACGCGCTTCGCCGAATTCCTTCCCGCCTTGCCGGCCTGCGAGATCGGCTGGACCTGGCTCGACCAGGCCCAGCA
CGGCAGCGGCCTGAACCGCATGATCAAGTACCTGATGCTCAAGCATGCCTTCGACAACCTGCGCATGGTCCGCGTGCAGC
TCAGCACGGCGGCGAGCAACCTGCGCGCCCAGGGCGCCATCGACAAGCTCGGCGCGCAGCGCGAGGGCGTGCTGCGCAAC
CACCGGCGGCTGGCCGGCGGGCGGCTAGACGACACATTCGTCTACAGCATCACCGACCACGAATGGCCGCAGGTCAAGGC
GACGCTGGAAGCCAGCTTCACCGGCTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10712.15 Da        Isoelectric Point: 4.6533

>AT230034 WP_046611946.1 NZ_CP090095:c1402009-1401710 [Neorhizobium galegae]
MTVETKKWDITEHLDTDERIALFLEAVFEDGDPAVIAAAIGDVARARGMSQIAKDAGLSRENLYRALSEGGNPEFATILK
VIRAIGYDLTIVPHGSAAR

Download         Length: 300 bp

>AT230034 NZ_CP124664:1916029-1916883 [Pseudomonas aeruginosa]
GTGCCGGACGAGACGAGCGGAGAACACACGCATTTCTGGCGCGCCGCCGAACTGGGCGGCGTCGAACTGCTGCACGCGCG
CTATGTGGAGCAGCGCTTCGCGCCGCACGTGCACAGCAGCTTCGCCCTAGTCATCATCGAGCAGGGCGCGCAGCGCTTCC
GCCATCGTGGCGGCGAGCACCTAGCCCCGCTGGGCAGCATGGTGCTGATCAACCCCGACGAAGTGCACACCGGCTCCAAG
GCCCATGATGCCGGTTGGCTCTATCGCGGCTACTACCCGGAAATGGAGCAGATCGACGGGATTCTCGACGAGCTGGAAAT
CCATCATGGCGGCGTGCCGCGTTTCGCCGACAGCGTGATCCACGACCAGCCCCTGGCACGCGCCTTCGTCCACTTGCACC
GCCTGCTGGCCGAGCATGCCGGCAGCCTGGAAACCCAGACCCGCTGGCGCGAGACGATGCTCGCCCTGTTCCGTCGCCAC
GCCCGCCTGCCAGAAGCGCCGAAGGCCGGGCAGGAGCCGTTGGCGGTGGCCCGCGCCCGCGAACTGCTGGCGGCGCGGTT
GCTCGATCCGCCTTCGCTGGAGGAACTGGCGGCGGCGGTCAATCTGTCCCCGTTCCATTTTGCCCGGGTCTTCCGTCGCG
CCACCGGCATGCCGCCCCACGCCTGGCTCAGGCAGCGCCGCCTGGAGCAGGCCAGGGCACTGCTCAAGAGCGGCCGGGCG
CCGCTGGAGGTGGCCCTGGAGCTGGGCTTCGCCGACCAGAGCCACCTCGGTCGCCAGTTCAAGCAGGCCTACGGGGTGGC
ACCGGGTGAATACCGCTCGGCCTGCGCGCGCTCGTCCTTGACGACATACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References