Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 913961..914688 Replicon chromosome
Accession NZ_CP090095
Organism Neorhizobium galegae strain 7g

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LZK81_RS04440 Protein ID WP_046625004.1
Coordinates 913961..914419 (-) Length 153 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LZK81_RS04445 Protein ID WP_233955309.1
Coordinates 914416..914688 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LZK81_RS04420 (LZK81_04420) 909638..911281 - 1644 WP_046603363.1 chaperonin GroEL -
LZK81_RS04425 (LZK81_04425) 911341..911637 - 297 WP_007752582.1 co-chaperone GroES -
LZK81_RS04430 (LZK81_04430) 912089..912937 + 849 WP_233955307.1 TIGR01459 family HAD-type hydrolase -
LZK81_RS04435 (LZK81_04435) 912976..913956 + 981 WP_233955308.1 bifunctional riboflavin kinase/FAD synthetase -
LZK81_RS04440 (LZK81_04440) 913961..914419 - 459 WP_046625004.1 type II toxin-antitoxin system VapC family toxin Toxin
LZK81_RS04445 (LZK81_04445) 914416..914688 - 273 WP_233955309.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LZK81_RS04450 (LZK81_04450) 914968..917871 + 2904 WP_233955310.1 isoleucine--tRNA ligase -
LZK81_RS04455 (LZK81_04455) 918006..918635 + 630 WP_046625007.1 hypothetical protein -
LZK81_RS04460 (LZK81_04460) 918643..919098 - 456 WP_233955311.1 nucleoside deaminase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-125)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(11-63)


Sequences

Toxin        


Download         Length: 153 a.a.        Molecular weight: 16881.92 Da        Isoelectric Point: 5.7749

>T230031 WP_046625004.1 NZ_CP090095:c914419-913961 [Neorhizobium galegae]
VIGWLLDTNVVAALINPNGAPSVKRWAAGQDEDRFFISILTLAEYDKGIENLPADDENRYRYAAARDALEDRFAGRTLSV
SDAIVRRWGAISGRVKQATSHAPPVIDTLFAATAIEHNLYLATRNVKDTRASGAAIFDPWQDDPERFPLSRR

Download         Length: 459 bp

>T230031 NZ_CP124663:c5443437-5443159 [Pseudomonas aeruginosa]
ATGATTCTGACCTTTCGCTGCGACGAGACTCGTCAGCTTTTTGAGACGGGTCTTTCGAGGCGGTGGGGAGCGATCCTCAC
AGTCGCTACGCGTAAGCTCGCAATGCTTCATGCGGCTACGGAGCTTCGAGACTTGCGCTCTCCACCTGGAAACCGGTTGG
AGCCGTTGCAGGGAAAGCGGGCGGGCCAACATAGCATCAGGATCAATGACCAGTGGCGTGTCTGTTTCGTCTGGACGGAT
GCTGGTCCCGAAGAAGTCGAAATAGTTGATTACCACTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10190.46 Da        Isoelectric Point: 5.7684

>AT230031 WP_233955309.1 NZ_CP090095:c914688-914416 [Neorhizobium galegae]
MPGKPTAHDNSWKLEDAKARFSEVVRRAHSEGPQRVTVRGRDSVVVISTEELERLTRAAPKKSFVEFMEGLGLDTLELER
EADRGRDIDL

Download         Length: 273 bp

>AT230031 NZ_CP124663:c5443147-5442842 [Pseudomonas aeruginosa]
ATGGCTACCAATGGTATGCGCCCCATCCATCCTGGGGAAATATTGCGCGATGAGTTTCTGATGGAGTTGGATATCTCTCC
AGCTGCTCTAGCACGCGCTTTGAAAGTCTCCGCTCCGACAGTGAACGATATCGTTCGTGAGCAGCGTGGTATCTCCGCAG
ATATGGCGATTCGTCTGGGGCGTTACTTTGATACGTCCGCTCAGTTCTGGATGAATCTCCAGAGTGAGTATTCGTTAGCA
ACTGCTTATGCGGCGAATGGCGAGCAGATCGAACATGAGATTGAGCCGCTGCTTGCTCAGGGATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References