Detailed information of TA system TA230001

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 462958..463594
• Replicon: chromosome
• Accession: NZ_CP090067
• Organism: Acinetobacter sp. SH20PTE14

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: LXF01_RS02285
• Protein ID: WP_078189263.1
• Coordinates: 463208..463594 (+)
• Length: 129 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: LXF01_RS02280
• Protein ID: WP_078189264.1
• Coordinates: 462958..463215 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LXF01_RS02260 (LXF01_02260)	458557..458922	+	366	WP_005012953.1	50S ribosomal protein L17	-
LXF01_RS02265 (LXF01_02265)	459139..460629	+	1491	WP_180173256.1	NAD(P)/FAD-dependent oxidoreductase	-
LXF01_RS02270 (LXF01_02270)	460762..461559	+	798	WP_233944975.1	alpha/beta hydrolase	-
LXF01_RS02275 (LXF01_02275)	461604..462776	-	1173	WP_180173257.1	acyl-CoA dehydrogenase family protein	-
LXF01_RS02280 (LXF01_02280)	462958..463215	+	258	WP_078189264.1	succinate dehydrogenase assembly factor 2	Antitoxin
LXF01_RS02285 (LXF01_02285)	463208..463594	+	387	WP_078189263.1	hypothetical protein	Toxin
LXF01_RS02290 (LXF01_02290)	464114..465196	+	1083	WP_180092976.1	hypothetical protein	-
LXF01_RS02295 (LXF01_02295)	465238..465810	+	573	WP_180173258.1	rhombosortase	-
LXF01_RS02300 (LXF01_02300)	466002..468203	+	2202	WP_180103016.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 129 a.a.
• Molecular weight: 15471.61 Da
• Isoelectric Point: 10.9047

>T230001 WP_078189263.1 NZ_CP090067:463208-463594 [Acinetobacter sp. SH20PTE14]
MDNRQFKLKRSFLSHAFQFFIFAVLMTLLYQLLTPMLWGIFFLIGLVVYVLFFRKHLHVTSLDYLDGTDWSLQRLNRPVQ
RVQISHILDHQMYIVVYFMHARAKPVIIWRDQLSLKQWKSLKVLAKMI

Nucleotide

• Length: 387 bp

>T230001 NZ_CP124658:2392180-2392755 [Pseudomonas aeruginosa]
ATGAGGCATTCCCCATTCACCGCCGTCTACGACGCGTGCGTTCTATATCCCGCGCCACTGCGGGATTTCCTGATGTGGCT
CGGCCTGTCTGGCCGCTTCCGGGCGCGGTGGAGCCAAGCCATTCATGAGGAGTGGAAACGCAACCTGTTGATCAACCGCC
CCGATCTCACCCGGGTTCAGGTCGACAGGACGTCGGATCTCATGGACCGGGCAATTCCGGACGGCTTGGTGGAGGGCTAC
GAAGCGCTCGTGGCAGGCCTGACATTGCCCGATCCGGACGACCGGCACGTCCTGGCTGCGGCGATTCGCTGCGGTGCGAG
CGTGATTGTGACGTTCAACGAACGGGATTTCCCGAACGATCTGCTGGCTCCGTACGGCATCGAATCGCAGCACCCCGATG
AGTTTGTGGACAACCTACTGGATCTGGACGCGGCCGCCGTGGTGTCGGCTGCGCAGCGCCAGCGTGCCCAACTCAAGCAT
CCGCCGATCGAGGTGGACCGCTATCTCGAAATCCTGCTGCGCCAGGGCCTTGTGCAAACGACCAAGGTGCTGGCGACCTA
TCGCACCATTCTCTGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10126.55 Da
• Isoelectric Point: 4.5716

>AT230001 WP_078189264.1 NZ_CP090067:462958-463215 [Acinetobacter sp. SH20PTE14]
MTDEISLEERKVIYRARRGLKEIDVYFDPYVKNYYLQADAAEKDMFAELVAAEDPDLLDWFMEVSEPPRPELKTFIQKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT230001 NZ_CP124658:2391713-2392183 [Pseudomonas aeruginosa]
ATGACCACCGCCACTGCCCAATCCAAGATGACCCTTCCCGCCGCGGGAGAGGTGAAGGCAGCCGTCCAGGGTCAACGTGC
CTTGGCGGCTTACCTCGCAACCCAGTTCGAGACGCAGCACATCCAGATCTTTGATGACCACAAACAGGCTCATCAGGTGG
AACTGCCTACCTCGGCTTTACGCCTGCTGGTCGACATCCTGGCCGAGTTGGCCGATGGCAATGCAGTAAAGGTGGTGCCC
GTCCATGCAGAGCTGACGACCCAAGAGGCGGCGGACTTGCTCAACGTGTCCCGTCCCCATTTCGTCAAGCTGCTCGAAGA
TGGGGTGTTGGCATTTCATCGCACCGGCAAGCACCGCAGGGTGAGGTTCGCCGATCTGATGCAGTACAAGGAAGCGCGCG
AGCGCGCCAGTGAGCAGGCGATGGCCGAACTCGCTCAGCAGTCGCAAGAGTTGGGAATGGGATACGAATGA