Detailed information of TA system TA229998

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 4722341..4722876
• Replicon: chromosome
• Accession: NZ_CP090065
• Organism: Pectobacterium polonicum strain BY21311

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: LW347_RS21305
• Protein ID: WP_103162646.1
• Coordinates: 4722589..4722876 (+)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: LW347_RS21300
• Protein ID: WP_137741168.1
• Coordinates: 4722341..4722592 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LW347_RS21275 (LW347_21255)	4717856..4718293	+	438	WP_137741173.1	ricin-type beta-trefoil lectin domain protein	-
LW347_RS21280 (LW347_21260)	4718976..4719599	-	624	WP_258883558.1	LysE family translocator	-
LW347_RS21285 (LW347_21265)	4719649..4720188	-	540	WP_258883559.1	CbrC family protein	-
LW347_RS21290 (LW347_21270)	4720389..4721144	+	756	WP_137741170.1	thiol:disulfide interchange protein DsbG	-
LW347_RS21295 (LW347_21275)	4721179..4722084	-	906	WP_258883560.1	siderophore-interacting protein	-
LW347_RS21300 (LW347_21280)	4722341..4722592	+	252	WP_137741168.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
LW347_RS21305 (LW347_21285)	4722589..4722876	+	288	WP_103162646.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
LW347_RS21310 (LW347_21290)	4722979..4724331	-	1353	WP_258883562.1	glutathione-disulfide reductase	-
LW347_RS21315 (LW347_21295)	4724460..4725302	-	843	WP_137741165.1	23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ	-
LW347_RS21320 (LW347_21300)	4725607..4725900	+	294	WP_258883563.1	DUF2623 domain-containing protein	-
LW347_RS21325 (LW347_21305)	4725911..4726732	-	822	WP_258883564.1	energy transducer TonB	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-84)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11083.21 Da
• Isoelectric Point: 10.4703

>T229998 WP_103162646.1 NZ_CP090065:4722589-4722876 [Pectobacterium polonicum]
MSYRVKFREDALKEWLKLDKAIQQQFAKKLKKCCENPHIPAAKLRGMKDCYKIKLRASGFRLVYEVIDDVLVIAVVAVGK
RERSGVYHLASERMR

Nucleotide

• Length: 288 bp

>T229998 NZ_CP124657:c6591337-6590813 [Pseudomonas aeruginosa]
ATGAAAATCATCGGAGTGCAGGACCTCCCCTGCTACCGAATGCACACTCCCAAGTGGTCCGTTGCGCCTACATCTGGAGC
TGGAGCTGCAACCCAGGGTGGCCGGGTTAACCGAAAGGGGCTAGAGGCTCTATACCTCTCGCTTGAGTCGGCAACGGCCA
TTGCTGAGTTTCAGCAAGGAAGCGCATTCCTTCCACCAGGTCTGCTGGTCAGCTATTCCCTCAGTCTGGACCGAGTGATC
GACTTCACCGGCGGCTATGACGATACCTGGGCCCCGATCTGGCAAGACTTTTTCTGCGACTGGAGAAAGATTCGCTTCAA
CGACGGCGTTGAACCGCCGAGCTGGATTGTCGGGGATCTGGCTATCGAGGCTGACTGTGCTGGGATTCTGTTCGAGTCCG
TTGCGAACCCTGGAGGTCGGAACCTGGTGCTTTTCACCGATCAGTTGCCGGTGCATGGGAATATTGTGGTAAACGATCCT
CGCGGGGATCTCCCTACCGACCAGTCATCTTGGACGCGCCCGTAG

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9131.54 Da
• Isoelectric Point: 4.1966

>AT229998 WP_137741168.1 NZ_CP090065:4722341-4722592 [Pectobacterium polonicum]
MPNIILSDTSASVSELKKNPMATVKAGDGLPVAILNRNQPAFYCIPADLYEKMLDALDDQELVKLIGERKNQPLVDVDLD
SFL

Nucleotide

• Length: 252 bp

>AT229998 NZ_CP124657:c6591729-6591334 [Pseudomonas aeruginosa]
ATGGCCAGCAAAGCCGTATTAGAGCTTCGCCCCACCAACTTCGCGGGCTTGATGGACGCTCTCAAAGAGGTGAACCGTGT
GATGTTCTCTCCTGAGCGCTTCCTCAAGGTTTTTTCGATGGACCAGCAGACCTTGGCGCTCCGGGCCCATGTCCATCGCA
ACACCGTGCGCAACGCGCCTGAATCGGAAAAGGTCCAAGCCTACATTCGTGATTCAGTGAAGGTTCTGCGTGCAGTGACC
GACATGGGCACGGACGTGACGAATGCCATCTTCTGGTTTAAGAACGAGCCTCTTTCCACGTTCAACTACAAGACCGCGGA
GGAAGTGGTCAGCGAAGGAAAAACCGAGCAGCTGATCGCTTTCCTTCAATCCTGGGAAGCTGGTGCGCAAGGATGA