Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 2976849..2977574 Replicon chromosome
Accession NZ_CP090065
Organism Pectobacterium polonicum strain BY21311

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag LW347_RS13425 Protein ID WP_258882570.1
Coordinates 2976849..2977169 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag LW347_RS13430 Protein ID WP_258882571.1
Coordinates 2977239..2977574 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LW347_RS13390 (LW347_13370) 2971918..2972121 - 204 WP_137742067.1 protein DsrB -
LW347_RS13395 (LW347_13375) 2972331..2973743 + 1413 WP_258882567.1 diguanylate cyclase -
LW347_RS13400 (LW347_13380) 2974020..2974238 + 219 WP_137742065.1 KTSC domain-containing protein -
LW347_RS13405 (LW347_13385) 2974445..2974801 + 357 WP_258882568.1 hypothetical protein -
LW347_RS13410 (LW347_13390) 2974855..2975138 + 284 Protein_2624 integrase -
LW347_RS13415 (LW347_13395) 2975567..2975764 - 198 WP_052325999.1 hypothetical protein -
LW347_RS13420 (LW347_13400) 2975898..2976731 - 834 WP_258882569.1 DUF4942 domain-containing protein -
LW347_RS13425 (LW347_13405) 2976849..2977169 - 321 WP_258882570.1 toxin Toxin
LW347_RS13430 (LW347_13410) 2977239..2977574 - 336 WP_258882571.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
LW347_RS13435 (LW347_13415) 2977614..2978087 - 474 WP_258882572.1 DNA repair protein RadC -
LW347_RS13440 (LW347_13420) 2978201..2978542 - 342 WP_258882573.1 hypothetical protein -
LW347_RS13445 (LW347_13425) 2978599..2979432 - 834 WP_125232326.1 hypothetical protein -
LW347_RS13450 (LW347_13430) 2979579..2979737 - 159 WP_154715508.1 hypothetical protein -
LW347_RS13455 (LW347_13435) 2979921..2980808 - 888 WP_130634221.1 50S ribosome-binding GTPase -
LW347_RS13460 (LW347_13440) 2980904..2981830 - 927 WP_258882574.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12043.79 Da        Isoelectric Point: 4.7768

>T229995 WP_258882570.1 NZ_CP090065:c2977169-2976849 [Pectobacterium polonicum]
MQTTPAIPPREDNPCPSPVAVWQQLLTYLLEKHYGLTLNDTPLCEENVIQEHIDAGVTLVNAVNFLVEKYELVRIDRNGF
NWQEQSPFLTAVDVLRARRVTGLLKA

Download         Length: 321 bp

>T229995 NZ_CP124657:3931397-3931975 [Pseudomonas aeruginosa]
ATGTCCCTCGAACTGCTGAGCAACCGCCTCGAATTCCTCCGCGAAGCCGAGCGCCTGAAAGACGTCCTGCGCTCCGCGCA
CACCTCCTCCGGCCGCCCGGAAAGCACCGCCGAACATAGCTGGCGGCTTTGCCTGATGGCACTGGCCTTCGAGGACCAAC
TGGCCGGCCTGGACCTCGGCAAGGTTCTGCGCATGTGCGTGGTCCACGACCTCGGCGAAGCGATCCACGGCGACATCCCC
GCCGTCGAGCAAGCGGCGCACCCGGACAAGGGCGAACAGGAACGCGCCGACCTGTTGCAGCTGACCCGTCATCTGGACAC
GCCGCTGCGCGATCGCCTGCTCGCCCTGTGGGACGAATACGAGCGCGGCGAGACCGCCGAAGCCCTGGCAGTGAAAGCGC
TGGACAAGCTGGAAACCCTGCTCCAGCACACCCAGGGCGACAATCCGGCGGACTTCGACTATGCCTTCAACCTCGACTAC
GGCCGTCGCTATACCGACCGCGCACCGCTGTTCAAGACCCTGCGCGAGTTACTCGACGCCAGGACCCGACAGCGCCTCGC
AGCTCGGCGCGACGCCTAG

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12452.23 Da        Isoelectric Point: 5.1574

>AT229995 WP_258882571.1 NZ_CP090065:c2977574-2977239 [Pectobacterium polonicum]
MPSSDSPEWGLKCAITPRFGARLVQEGNRLHYLVDRANIVGKFSKTEAQSLERCFPELIKLLEQKLRTGELNPRQQDCII
LHCDECTCEADTLGSFGYVYIVIYPSSAAAE

Download         Length: 336 bp

>AT229995 NZ_CP124657:3930755-3931309 [Pseudomonas aeruginosa]
ATGACCGAGCCTCTCCCTTCTTCGTCCCTGGGCCCCGCCCTGCGTCGCTGGCGCCTGCTGCACCGGGTCAAGCAAACGCA
TGCCGCCGAATTGCTCGGCGTGGCGCAATCGACCATCTCGCGCTGGGAGTCCGGTACCCAGGCGCTGCTGGTGGAGGAAC
GGGCACGCCTGGAGCGTCTGCTCGGCGCCCGCCTGGAAGCCGCCGCCGACCAGGCACTGGCCCGCCTGGTCGAGGCCAAC
CCGCAACCCGTGCACCTGATCTGCGACCTCACCCATCGCCTGTTGGCCTGTTCGCCGGCACGCGCCGCGCAATTCGGCGT
GCCTCTCGGCGAACTGCTCGACCGTTCGCTGTGGCCCTATTGCAGCGAGGAAATCCTCCGCCAGGAAGCCACCCTCGAGG
AACTCGGCTGGCGCGAACTGCTGGCACCGCCGGCGCTGGAGTTCGCCAGCGGAGCGAACGCCTCGGCCATCGTGCCGATC
CGGCGCAGCCGTTGCCGCTGGACCCGCATGACCCTCTCGGACGGACGCGCGGTGCGCCTGGTGGAAACCCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References