Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VII Classification (family/domain) HepT-MntA/HepT(toxin)
Location 1586915..1587714 Replicon chromosome
Accession NZ_CP090065
Organism Pectobacterium polonicum strain BY21311

Toxin (Protein)


Gene name hepT Uniprot ID -
Locus tag LW347_RS07130 Protein ID WP_258884596.1
Coordinates 1586915..1587334 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name mntA Uniprot ID -
Locus tag LW347_RS07135 Protein ID WP_258884597.1
Coordinates 1587331..1587714 (-) Length 128 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LW347_RS07110 (LW347_07095) 1582107..1582667 + 561 Protein_1375 uridine kinase -
LW347_RS07115 (LW347_07100) 1582776..1583357 + 582 WP_005974037.1 dCTP deaminase -
LW347_RS07120 (LW347_07105) 1583421..1585256 + 1836 WP_258884594.1 outer membrane assembly protein AsmA -
LW347_RS07125 (LW347_07110) 1585522..1586874 + 1353 WP_258884595.1 anaerobic C4-dicarboxylate transporter DcuC -
LW347_RS07130 (LW347_07115) 1586915..1587334 - 420 WP_258884596.1 DUF86 domain-containing protein Toxin
LW347_RS07135 (LW347_07120) 1587331..1587714 - 384 WP_258884597.1 nucleotidyltransferase domain-containing protein Antitoxin
LW347_RS07140 (LW347_07125) 1587828..1589414 - 1587 WP_258884598.1 TerC family protein -
LW347_RS07145 (LW347_07130) 1590066..1591145 + 1080 WP_258884599.1 UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase -
LW347_RS07150 (LW347_07135) 1591270..1592406 + 1137 WP_258884600.1 polysaccharide export protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease HepT-like

(13-130)

Antitoxin

Polymerase beta, nucleotidyltransferase

(4-93)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 16097.45 Da        Isoelectric Point: 6.9686

>T229994 WP_258884596.1 NZ_CP090065:c1587334-1586915 [Pectobacterium polonicum]
MTDILINKSSTIQRCLRRIREEFDTEEGFRQNFTKQDSVILNIQRACEAAIDIANYLIRIKKLGIPQSSRDSFALLSANQ
IITIDLSDNLQKMVGLRNIAVHDYQALNLDIVIHVISHRLSDFEHFIKEIVRYSDSQHL

Download         Length: 420 bp

>T229994 NZ_CP124657:1916752-1917339 [Pseudomonas aeruginosa]
ATGTCGAGGAGGGCGCCCATGTTCAAGCCGCTACCGATCACCCTGCAGCGCGGAGCCTTGCGTCTCGAGCCGCTGGTGGA
AGCGGACATTCCCGAGCTGGTGAGCCTCGCCGAAGCCAACCGCGAGGCGCTGCAGTACATGGACGGACCGACGCGGCCGG
ACTGGTACCGCCAGAGCCTCGCCGAGCAGCGCGAGGGCAGGGCGTTGCCGCTCGCCGTCCGCCTCGGCGTGCAACTGGTC
GGGACCACGCGCTTCGCCGAATTCCTTCCCGCCTTGCCGGCCTGCGAGATCGGCTGGACCTGGCTCGACCAGGCCCAGCA
CGGCAGCGGCCTGAACCGCATGATCAAGTACCTGATGCTCAAGCATGCCTTCGACAACCTGCGCATGGTCCGCGTGCAGC
TCAGCACGGCGGCGAGCAACCTGCGCGCCCAGGGCGCCATCGACAAGCTCGGCGCGCAGCGCGAGGGCGTGCTGCGCAAC
CACCGGCGGCTGGCCGGCGGGCGGCTAGACGACACCTTCGTCTACAGCATCACCGACCACGAATGGCCGCAGGTCAAGGC
GGCGCTGGAAGCCAGCTTCACCGGCTGA

Antitoxin


Download         Length: 128 a.a.        Molecular weight: 14361.57 Da        Isoelectric Point: 4.9205

>AT229994 WP_258884597.1 NZ_CP090065:c1587714-1587331 [Pectobacterium polonicum]
MFDEIVSTLKKQIPDIRMVYLFGSQATGNARADSDIDIAIMATRTLAPVERWELSNQLAKAMGRDVDLVDLLQASTVLKM
EIVRNGKLLYDAETAAGEFEMITLSMYQHLQKERADIIRSFHQDLKA

Download         Length: 384 bp

>AT229994 NZ_CP124657:1917406-1918260 [Pseudomonas aeruginosa]
GTGCCGGACGAGACGAGCGGAGAACACACGCATTTCTGGCGCGCCGCCGAACTGGGCGGCGTCGAACTGCTGCACGCGCG
CTATGTGGAGCAGCGCTTCGCGCCGCACGTGCACAGCAGCTTCGCCCTGGTCATCATCGAGCAGGGCGCGCAGCGCTTCC
GCCATCGTGGCGGCGAGCACCTGGCCCCGCTGGGCAGCATGGTGCTGATCAACCCCGACGAAGTGCACACCGGCTCCAAG
GCCCATGATGCCGGTTGGCTCTATCGCGGCTACTACCCGGAGATGGAGCAGATCGACGGGATTCTCGACGAGCTGGAAAT
CCATCATGGCGGCGTGCCGCGTTTCGCCGACAGCGTGATCCACGACCAGCCCCTGGCACGCGCCTTCGTCCACTTGCACC
GCCTGCTGGCCGAGCATGCCGGCAGCCTGGAAACCCAGACCCGCTGGCGCGAGACGGTGCTCGCCCTGTTCCGTCGCCAC
GCCCGCCTGCCAGAAGCGCCGAAGGCCGGGCAGGAGCCGTTGGCGGTGGCCCGTGCCCGCGAACTGCTGGCGGCGCGGTT
GCTCGATCCGCCTTCGCTGGAGGAACTGGCGGCGGCGGTCAATCTGTCCCCGTTCCATTTTGCCCGGGTCTTCCGTCGCG
CCACCGGCATGCCGCCCCACGCCTGGCTCAGGCAGCGCCGCCTGGAGCAGGCCAGGGCACTGCTCAAGAGCGGCCGGGCG
CCGCTGGAGGTGGCCCTGGAGCTGGGCTTCGCCGACCAGAGCCACCTCGGTCGCCAGTTCAAGCAGGCCTACGGGGTGGC
ACCGGGTGAATACCGCTCGGCCTGCGCGCGCTCGTCCTTGACGACATACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References