Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 644723..645249 Replicon chromosome
Accession NZ_CP090065
Organism Pectobacterium polonicum strain BY21311

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag LW347_RS02885 Protein ID WP_258883946.1
Coordinates 644723..645028 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag LW347_RS02890 Protein ID WP_258883947.1
Coordinates 645031..645249 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LW347_RS02875 (LW347_02875) 641388..643337 + 1950 WP_258883944.1 helicase-related protein -
LW347_RS02880 (LW347_02880) 643339..644598 + 1260 WP_258883945.1 GIY-YIG nuclease family protein -
LW347_RS02885 (LW347_02885) 644723..645028 - 306 WP_258883946.1 type II toxin-antitoxin system toxin CcdB Toxin
LW347_RS02890 (LW347_02890) 645031..645249 - 219 WP_258883947.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin
LW347_RS02895 (LW347_02895) 645338..645720 - 383 Protein_555 molybdopterin-guanine dinucleotide biosynthesis protein MobC -
LW347_RS02900 (LW347_02900) 645719..646084 - 366 Protein_556 Arm DNA-binding domain-containing protein -
LW347_RS02905 (LW347_02905) 646585..647733 + 1149 WP_258883948.1 Fic family protein -
LW347_RS02910 (LW347_02910) 648138..648308 + 171 Protein_558 IS630 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 634441..652418 17977


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-100)

Antitoxin

Post-segregation antitoxin CcdA

(2-72)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11678.57 Da        Isoelectric Point: 4.3637

>T229989 WP_258883946.1 NZ_CP090065:c645028-644723 [Pectobacterium polonicum]
MQFIVYQYKQASHYKMFVDVQSDIVETLKRCMAIPLIESHYLSEKVNKVLFPLIRIDGEDYRLMTTELSSVPVEVIGEVI
ADLGDYADEVKDALNLMFWGI

Download         Length: 306 bp

>T229989 NZ_CP124655:c5012395-5011808 [Pseudomonas aeruginosa]
ATGTCGAGGAGGGCGCCCATGTTCAAGCCGCTACCGATCACCCTGCAGCGCGGAGCCTTGCGTCTCGAGCCGCTGGTGGA
AGCGGACATTCCCGAGCTGGTGAGCCTCGCCGAAGCCAACCGCGAGGCGCTGCAGTACATGGACGGACCGACGCGGCCGG
ACTGGTACCGCCAGAGCCTCGCCGAGCAGCGCGAGGGCAGGGCGTTGCCGCTCGCCGTCCGCCTCGGCGTGCAACTGGTC
GGGACCACGCGCTTCGCCGAATTCCTTCCCGCCTTGCCGGCCTGCGAGATCGGCTGGACCTGGCTCGACCAGGCCCAGCA
CGGCAGCGGCCTGAACCGCATGATCAAGTACCTGATGCTCAAGCATGCCTTCGACAACCTGCGCATGGTCCGCGTGCAGC
TCAGCACGGCGGCGAGCAACCTGCGCGCCCAGGGCGCCATCGACAAGCTCGGCGCGCAGCGCGAGGGCGTGCTGCGCAAC
CACCGGCGGCTGGCCGGCGGGCGGCTAGACGACACCTTCGTCTACAGCATCACCGACCACGAATGGCCGCAGGTCAAGGC
GGCGCTGGAAGCCAGCTTCACCGGCTGA

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8264.28 Da        Isoelectric Point: 7.2033

>AT229989 WP_258883947.1 NZ_CP090065:c645249-645031 [Pectobacterium polonicum]
MKHRVSVTVDKDNYQVLSAAGINISGLVNDAIGKEARRIRTEMWKKEKSEGMEDVARFIAQHDSFADENRNW

Download         Length: 219 bp

>AT229989 NZ_CP124655:c5011741-5010887 [Pseudomonas aeruginosa]
GTGCCGGACGAGACGAGCGGAGAACACACGCATTTCTGGCGCGCCGCCGAACTGGGCGGCGTCGAACTGCTGCACGCGCG
CTATGTGGAGCAGCGCTTCGCGCCGCACGTGCACAGCAGCTTCGCCCTGGTCATCATCGAGCAGGGCGCGCAGCGCTTCC
GCCATCGTGGCGGCGAGCACCTGGCCCCGCTGGGCAGCATGGTGCTGATCAACCCCGACGAAGTGCACACCGGCTCCAAG
GCCCATGATGCCGGTTGGCTCTATCGCGGCTACTACCCGGAGATGGAGCAGATCGACGGGATTCTCGACGAGCTGGAAAT
CCATCATGGCGGCGTGCCGCGTTTCGCCGACAGCGTGATCCACGACCAGCCCCTGGCACGCGCCTTCGTCCACTTGCACC
GCCTGCTGGCCGAGCATGCCGGCAGCCTGGAAACCCAGACCCGCTGGCGCGAGACGGTGCTCGCCCTGTTCCGTCGCCAC
GCCCGCCTGCCAGAAGCGCCGAAGGCCGGGCAGGAGCCGTTGGCGGTGGCCCGTGCCCGCGAACTGCTGGCGGCGCGGTT
GCTCGATCCGCCTTCGCTGGAGGAACTGGCGGCGGCGGTCAATCTGTCCCCGTTCCATTTTGCCCGGGTCTTCCGTCGCG
CCACCGGCATGCCGCCCCACGCCTGGCTCAGGCAGCGCCGCCTGGAGCAGGCCAGGGCACTGCTCAAGAGCGGCCGGGCG
CCGCTGGAGGTGGCCCTGGAGCTGGGCTTCGCCGACCAGAGCCACCTCGGTCGCCAGTTCAAGCAGGCCTACGGGGTGGC
ACCGGGTGAATACCGCTCGGCCTGCGCGCGCTCGTCCTTGACGACATACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References