Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 4719777..4720312 Replicon chromosome
Accession NZ_CP090028
Organism Serratia ureilytica strain W051

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LSG14_RS22565 Protein ID WP_164057663.1
Coordinates 4719777..4720052 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LSG14_RS22570 Protein ID WP_047025978.1
Coordinates 4720052..4720312 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LSG14_RS22545 4715667..4716218 + 552 WP_072626481.1 isochorismatase family protein -
LSG14_RS22550 4716221..4717144 + 924 WP_187048495.1 DJ-1/PfpI family protein -
LSG14_RS22555 4717139..4718131 - 993 WP_187048494.1 acyltransferase -
LSG14_RS22560 4718349..4719596 + 1248 WP_033633516.1 MFS transporter -
LSG14_RS22565 4719777..4720052 - 276 WP_164057663.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LSG14_RS22570 4720052..4720312 - 261 WP_047025978.1 ribbon-helix-helix domain-containing protein Antitoxin
LSG14_RS22575 4720395..4722236 - 1842 WP_187048493.1 selenocysteine-specific translation elongation factor -
LSG14_RS22580 4722233..4723627 - 1395 WP_042783408.1 L-seryl-tRNA(Sec) selenium transferase -
LSG14_RS22585 4723697..4724302 - 606 WP_033645111.1 glutathione S-transferase -
LSG14_RS22590 4724343..4724993 - 651 WP_033645112.1 DcrB-related protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10616.41 Da        Isoelectric Point: 10.3377

>T229939 WP_164057663.1 NZ_CP090028:c4720052-4719777 [Serratia ureilytica]
MELKWTSKVLPDLARLFEFLALANRTAAANSVKALVAAPKALLDNPRLGERLDEFLPQEVRRILVGRYEIRYQVQPATIY
VLRIWHTREER

Download         Length: 276 bp

>T229939 NZ_CP124646:c5803335-5803057 [Pseudomonas aeruginosa]
ATGATTCTGACCTTTCGCTGCGACGAGACTCGTCAGCTTTTTGAGACGGGTCTTTCGAGGCGGTGGGGAGCGATCCTCAC
AGTCGCTACGCGTAAGCTCGCAATGCTTCATGCGGCTACGGAGCTTCGAGACTTGCGCTCTCCACCTGGAAACCGGTTGG
AGCCGTTGCAGGGAAAGCGGGCGGGCCAACATAGCATCAGGATCAATGACCAGTGGCGTGTCTGTTTCGTCTGGACGGAT
GCGGGTCCCGAAGAAGTCGAAATAGTTGATTACCACTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9667.98 Da        Isoelectric Point: 4.5201

>AT229939 WP_047025978.1 NZ_CP090028:c4720312-4720052 [Serratia ureilytica]
MNTKVITAHVPLPLAEKVDEMAAKLDRSRGWIVKQALAAWLEQEEERRRLTLAALADVEQQNVIDHESVEAWAASLDSDE
PLPVPR

Download         Length: 261 bp

>AT229939 NZ_CP124646:c5803045-5802740 [Pseudomonas aeruginosa]
ATGGCTACCAATGGTATGCGCCCCATCCATCCTGGGGAAATATTGCGCGATGAGTTTCTGATGGAGTTGGATATCTCTCC
AGCTGCTCTAGCACGCGCTTTGAAAGTCTCCGCTCCGACAGTGAACGATATCGTTCGTGAGCAGCGTGGTATCTCCGCAG
ATATGGCGATTCGTCTGGGGCGTTACTTTGATACGTCCGCTCAGTTCTGGATGAATCTCCAGAGTGAGTACTCGTTAGCA
ACTGCTTATGCGGCGAATGGCGAGCAGATCGAACATGAGATTGAGCCGCTGCTTGCTCACGGATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References