Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 3213338..3213886 Replicon chromosome
Accession NZ_CP090028
Organism Serratia ureilytica strain W051

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag LSG14_RS15285 Protein ID WP_028127948.1
Coordinates 3213338..3213640 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag LSG14_RS15290 Protein ID WP_025302143.1
Coordinates 3213650..3213886 (-) Length 79 a.a.

Genomic Context

LSG14_RS15270LSG14_RS15275LSG14_RS15280LSG14_RS15265LSG14_RS15285LSG14_RS15290LSG14_RS15295LSG14_RS15300LSG14_RS15305
Location: 3210370..3211290 (921 bp)
Type: Others
Protein ID: WP_164107264.1
Location: 3211321..3212445 (1125 bp)
Type: Others
Protein ID: WP_016928454.1
Location: 3212460..3213302 (843 bp)
Type: Others
Protein ID: WP_015377214.1
Location: 3209107..3210264 (1158 bp)
Type: Others
Protein ID: WP_198772144.1
Location: 3213338..3213640 (303 bp)
Type: Toxin
Protein ID: WP_028127948.1
Location: 3213650..3213886 (237 bp)
Type: Antitoxin
Protein ID: WP_025302143.1
Location: 3213973..3214881 (909 bp)
Type: Others
Protein ID: WP_171403307.1
Location: 3214891..3215811 (921 bp)
Type: Others
Protein ID: WP_025302141.1
Location: 3215864..3217399 (1536 bp)
Type: Others
Protein ID: WP_060659741.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LSG14_RS152653209107..3210264-1158WP_198772144.1YbfB/YjiJ family MFS transporter-
LSG14_RS152703210370..3211290+921WP_164107264.1LysR family transcriptional regulator-
LSG14_RS152753211321..3212445+1125WP_016928454.1S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase-
LSG14_RS152803212460..3213302+843WP_015377214.1S-formylglutathione hydrolase-
LSG14_RS152853213338..3213640-303WP_028127948.1CcdB family proteinToxin
LSG14_RS152903213650..3213886-237WP_025302143.1type II toxin-antitoxin system CcdA family antitoxinAntitoxin
LSG14_RS152953213973..3214881-909WP_171403307.1glutathione ABC transporter permease GsiD-
LSG14_RS153003214891..3215811-921WP_025302141.1glutathione ABC transporter permease GsiC-
LSG14_RS153053215864..3217399-1536WP_060659741.1glutathione ABC transporter substrate-binding protein GsiB-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-99)

Antitoxin

Post-segregation antitoxin CcdA

(8-78)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11210.98 Da        Isoelectric Point: 5.0196

>T229937 WP_028127948.1 NZ_CP090028:c3213640-3213338 [Serratia ureilytica]
ITVYDNTYPASAYPYLLDVQSDLIDVLSTRLMIPLYALDNVRVKISARLCPEIEVNGEKFLVMTHEMAAVRISQIGKAVG
NVNEHRNQIKAAIDFLIDGF

Download         Length: 303 bp

>T229937 NZ_CP124646:c3142301-3141723 [Pseudomonas aeruginosa]
ATGTCCCTCGAACTGCTGAGCAACCGCCTCGAATTCCTCCGCGAAGCCGAACGCCTGAAAGACGTCCTGCGCTCCGCGCA
CACCTCCTCCGGCCGCCCGGAAAGCACCGCCGAACATAGCTGGCGGCTGTGCCTGATGGCACTGGCCTTCGAGGACCAAC
TGGCCGGCCTGGACCTCGGCAAGGTTCTGCGCATGTGCGTGGTCCACGACCTCGGCGAAGCGATCCACGGCGACATCCCC
GCCGTCGAGCAAGCCGCGCACCCGGACAAGGGCGAACAGGAACGCGCCGACCTGTTGCAGCTGACCCGTCATCTGGACAC
GCCGCTGCGCGATCGCCTGCTCGCCCTGTGGGACGAATACGAGCGCGGCGAGACCGCCGAAGCCCTGGCAGTGAAAGCGC
TGGACAAGCTGGAAACCCTGCTCCAGCACACCCAGGGCGACAATCCGGCGGACTTCGACTATGCCTTCAACCTCGACTAC
GGCCGTCGCTATACCGACCGCGCACCGCTGTTCAAGACCCTGCGCGAGTTACTCGACGCCAGGACCCGACAGCGCCTCGC
AGCTCGGCGCGACGCCTAG

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8967.04 Da        Isoelectric Point: 5.0807

>AT229937 WP_025302143.1 NZ_CP090028:c3213886-3213650 [Serratia ureilytica]
MANSNVTKKTVNVTIDRDLFQRAKSLGVNVSSVLTDALSVRVRDIEIQQWREQNRAALEELNRITEENGLLSDEYRTF

Download         Length: 237 bp

>AT229937 NZ_CP124646:c3142943-3142389 [Pseudomonas aeruginosa]
ATGACCGAGCCTCTCCCTTCTTCGTCCCTGGGCCCCGCCCTGCGTCGCTGGCGCCTGCTGCACCGGGTCAAGCAAACGCA
TGCCGCCGAATTGCTCGGCGTGGCGCAATCGACCATCTCGCGCTGGGAGTCCGGTACCCAGGCGCTGCTGGTGGAGGAAC
GGGCACGCCTGGAGCGTCTGCTCGGCGCCCGCCTGGAAGCCGCCGCCGACCAGGCACTGGCCCGCCTGGTCGAGGCCAAC
CCGCAACCCGTGCACCTGATCTGCGACCTCACCCATCGCTTGCTGGCCTGTTCGCCGGCACGCGCCGCGCAATTCGGCGT
GCCCCTCGGCGAACTGCTCGACCGTTCGCTGTGGCCCTATTGCAGCGAGGAAATCCTCCGCCAGGAAGCCACCCTCGAGG
AACTCGGCTGGCGCGAACTGCTGGCACCGCCGGCGCTGGAGTTCGCCAGCGGAGCGAACGCCTCGGCCATCGTGCCGATC
CGGCGCAGCCGTTGCCGCTGGACCCGCATGACCCTCTCGGACGGACGCGCGGTGCGCCTGGTGGAAACCCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References