Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RelE(toxin)
Location 79998..80563 Replicon chromosome
Accession NZ_CP090028
Organism Serratia ureilytica strain W051

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag LSG14_RS00350 Protein ID WP_182265722.1
Coordinates 79998..80276 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag LSG14_RS00355 Protein ID WP_182074225.1
Coordinates 80294..80563 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LSG14_RS00330 76170..76508 - 339 WP_025304525.1 PTS lactose/cellobiose transporter subunit IIA -
LSG14_RS00335 76862..77431 + 570 WP_033636286.1 peptidylprolyl isomerase A -
LSG14_RS00340 77587..79272 + 1686 WP_033651731.1 sensor histidine kinase -
LSG14_RS00345 79272..79997 + 726 WP_046688553.1 two-component system response regulator BtsR -
LSG14_RS00350 79998..80276 - 279 WP_182265722.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LSG14_RS00355 80294..80563 - 270 WP_182074225.1 hypothetical protein Antitoxin
LSG14_RS00360 80782..82305 + 1524 WP_033645261.1 DUF853 family protein -
LSG14_RS00365 82378..82953 + 576 WP_033645386.1 aminodeoxychorismate synthase component II -
LSG14_RS00370 83085..84302 + 1218 WP_187048451.1 aspartate aminotransferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10289.01 Da        Isoelectric Point: 10.0357

>T229922 WP_182265722.1 NZ_CP090028:c80276-79998 [Serratia ureilytica]
VKLIWTEPAIADRLAIYEWLELKNPAAAAENDVKIADAAARLVHHPASGKTGRIAGTRELVISPSYLLVYEWAAQRVIIL
AIVHTRRRWPPV

Download         Length: 279 bp

>T229922 NZ_CP124638:c5441602-5441324 [Pseudomonas aeruginosa]
ATGATTCTGACCTTTCGCTGCGACGAGACTCGTCAGCTTTTTGAGACGGGTCTTTCGAGGCGGTGGGGAGCGATCCTCAC
AGTCGCTACGCGTAAGCTCGCAATGCTTCATGCGGCTACGGAGCTTCGAGACTTGCGCTCTCCACCTGGAAACCGCTTGG
AGCCGTTGCAGGGAAAGCGGGCGGGCCAACATAGCATCAGGATCAATGACCAGTGGCGTGTCTGTTTCGTCTGGACGGAT
GCGGGTCCCGAAGAAGTCGAAATAGTTGATTACCACTGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10311.56 Da        Isoelectric Point: 5.2791

>AT229922 WP_182074225.1 NZ_CP090028:c80563-80294 [Serratia ureilytica]
MPESTVVIRVDEELKTAFASAAKAADRTASQLLRDFMREFVSRQAQQEEYDQWLREKVEVSRKALREGKLADDEEVAAYF
AERRAKSTR

Download         Length: 270 bp

>AT229922 NZ_CP124638:c5441312-5441007 [Pseudomonas aeruginosa]
ATGGCTACCAATGGTATGCGCCCCATCCATCCTGGGGAAATATTGCGCGATGAGTTTCTGATGGAGTTGGATATCTCTCC
AGCTGCTCTAGCACGCGCTTTGAAAGTCTCCGCTCCGACAGTGAACGATATCGTTCGTGAGCAGCGTGGTATCTCCGCAG
ATATGGCGATTCGTCTGGGGCGTTACTTTGATACGTCCGCTCAGTTCTGGATGAATCTCCAGAGTGAGTACTCGTTAGCA
ACTGCTTATGCGGCGAATGGCGAGCAGATCGAACATGAGATTGAGCCGCTGCTTGCTCAGGGATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References