Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-PumB/upstrm_HI1419-dnstrm_HI1420
Location 284440..285088 Replicon chromosome
Accession NC_011071
Organism Stenotrophomonas maltophilia R551-3

Toxin (Protein)


Gene name relE Uniprot ID B4ST98
Locus tag SMAL_RS01195 Protein ID WP_012509779.1
Coordinates 284440..284727 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID B4ST99
Locus tag SMAL_RS01200 Protein ID WP_012509780.1
Coordinates 284786..285088 (+) Length 101 a.a.

Genomic Context

SMAL_RS01175SMAL_RS01180SMAL_RS01185SMAL_RS01195SMAL_RS01200SMAL_RS21000SMAL_RS01210SMAL_RS01215SMAL_RS01220SMAL_RS01230SMAL_RS01165SMAL_RS01170SMAL_RS01225
Location: 281586..282554 (969 bp)
Type: Others
Protein ID: WP_012509776.1
Location: 282551..283282 (732 bp)
Type: Others
Protein ID: WP_012509777.1
Location: 283292..284140 (849 bp)
Type: Others
Protein ID: WP_012509778.1
Location: 284440..284727 (288 bp)
Type: Toxin
Protein ID: WP_012509779.1
Location: 284786..285088 (303 bp)
Type: Antitoxin
Protein ID: WP_012509780.1
Location: 285149..285634 (486 bp)
Type: Others
Protein ID: WP_157628455.1
Location: 285891..286811 (921 bp)
Type: Others
Protein ID: WP_004137058.1
Location: 286974..287111 (138 bp)
Type: Others
Protein ID: WP_008266021.1
Location: 287315..287536 (222 bp)
Type: Others
Protein ID: WP_004137109.1
Location: 288519..289811 (1293 bp)
Type: Others
Protein ID: WP_004137142.1
Location: 280402..281148 (747 bp)
Type: Others
Protein ID: WP_041864460.1
Location: 281157..281441 (285 bp)
Type: Others
Protein ID: WP_012509775.1
Location: 287610..288410 (801 bp)
Type: Others
Protein ID: WP_012509781.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
SMAL_RS01165280402..281148-747WP_041864460.1zinc-dependent peptidase-
SMAL_RS01170281157..281441-285WP_012509775.1hypothetical protein-
SMAL_RS01175281586..282554+969WP_012509776.1bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor-
SMAL_RS01180282551..283282+732WP_012509777.1type III pantothenate kinase-
SMAL_RS01185283292..284140+849WP_012509778.1SPOR domain-containing protein-
SMAL_RS01195284440..284727+288WP_012509779.1type II toxin-antitoxin system RelE/ParE family toxinToxin
SMAL_RS01200284786..285088+303WP_012509780.1putative addiction module antidote proteinAntitoxin
SMAL_RS21000285149..285634+486WP_157628455.1hypothetical protein-
SMAL_RS01210285891..286811+921WP_004137058.1arginase-
SMAL_RS01215286974..287111+138WP_008266021.1entericidin A/B family lipoprotein-
SMAL_RS01220287315..287536+222WP_004137109.1CsbD family protein-
SMAL_RS01225287610..288410-801WP_012509781.1hypothetical protein-
SMAL_RS01230288519..289811+1293WP_004137142.1tryptophan--tRNA ligase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-90)

Antitoxin

Cro/C1-type helix-turn-helix domain

(43-95)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10835.41 Da        Isoelectric Point: 10.8940

>T22992 WP_012509779.1 NC_011071:284440-284727 [Stenotrophomonas maltophilia R551-3]
MKIQRTRQFATWIDALKDVTGRARILARIGRLSEGHLGDHRYLADGVSELRIDVGPGYRVYYTQRGRQWVILLAGGDKGS
QQRDIEKAREIARAL

Download         Length: 288 bp

>T22992 NC_011071:284440-284727 [Stenotrophomonas maltophilia R551-3]
ATGAAGATCCAGCGTACCCGTCAGTTCGCGACATGGATTGACGCTCTCAAGGACGTAACCGGGCGCGCTCGCATCCTGGC
CCGCATCGGTCGGCTCAGCGAAGGCCATCTGGGCGATCACCGCTATCTGGCCGATGGCGTTTCCGAACTGCGCATCGATG
TGGGACCGGGTTACCGCGTGTACTACACCCAGCGCGGCAGGCAGTGGGTGATTCTGCTGGCTGGCGGCGACAAGGGTTCA
CAGCAACGCGATATCGAGAAGGCCAGGGAGATTGCGCGTGCCCTGTAG

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10734.37 Da        Isoelectric Point: 8.0343

>AT22992 WP_012509780.1 NC_011071:284786-285088 [Stenotrophomonas maltophilia R551-3]
MVIKKKVELKAFDVAEHLRTPEEMAAYLDACIEESDGDSAFIAKALGDIARAQGMSKVARAAGLSRESLYRALSGERSPD
FATILKVTRALGVRLHASAA

Download         Length: 303 bp

>AT22992 NC_011071:284786-285088 [Stenotrophomonas maltophilia R551-3]
ATGGTCATCAAGAAGAAAGTTGAACTCAAAGCATTTGACGTGGCCGAGCACCTTCGCACACCGGAGGAGATGGCGGCCTA
TCTCGATGCCTGCATCGAAGAAAGCGATGGCGATTCTGCGTTCATTGCCAAGGCGCTCGGCGACATCGCGCGCGCTCAAG
GGATGAGCAAGGTCGCACGAGCGGCGGGCCTCTCGCGTGAGAGTCTGTATCGCGCACTGTCGGGCGAGCGCAGCCCTGAT
TTTGCGACCATCCTCAAAGTGACCCGCGCCTTGGGTGTTCGCCTGCATGCCAGCGCAGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBB4ST98

Antitoxin

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Source
ID
Structure
AlphaFold DBB4ST99

References