Detailed information of TA system TA229919

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-CC2985
• Location: 264560..265106
• Replicon: plasmid p1
• Accession: NZ_CP090023
• Organism: Cereibacter azotoformans strain SY5

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: LV780_RS20670
• Protein ID: WP_011910870.1
• Coordinates: 264560..264853 (-)
• Length: 98 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: LV780_RS20675
• Protein ID: WP_011910869.1
• Coordinates: 264840..265106 (-)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LV780_RS20645 (LV780_20645)	259771..259914	-	144	WP_181969655.1	hypothetical protein	-
LV780_RS20650 (LV780_20650)	260129..261331	+	1203	WP_117345263.1	Fic family protein	-
LV780_RS20655 (LV780_20655)	261425..262648	-	1224	WP_011910873.1	AAA family ATPase	-
LV780_RS20660 (LV780_20660)	262873..263682	+	810	WP_233864264.1	hypothetical protein	-
LV780_RS20665 (LV780_20665)	264227..264409	-	183	WP_044249733.1	hypothetical protein	-
LV780_RS20670 (LV780_20670)	264560..264853	-	294	WP_011910870.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
LV780_RS20675 (LV780_20675)	264840..265106	-	267	WP_011910869.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
LV780_RS20680 (LV780_20680)	265782..267155	+	1374	WP_233864266.1	Fic family protein	-
LV780_RS20685 (LV780_20685)	267624..268955	-	1332	WP_011910866.1	HipA domain-containing protein	-
LV780_RS20690 (LV780_20690)	269072..269266	-	195	Protein_253	helix-turn-helix domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..298439	298439

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-92)

Antitoxin

• Antitoxin ParD (2-80)

Sequences

Toxin

Protein

• Length: 98 a.a.
• Molecular weight: 11036.64 Da
• Isoelectric Point: 7.4636

>T229919 WP_011910870.1 NZ_CP090023:c264853-264560 [Cereibacter azotoformans]
VTKIDFTRDAERDLIDIFLYGIEHFGPVQAERYTKTLNAKIDMAAEHPDFGADYGFVIKGVRRYEAVSHAIYYRSTGVGI
LVLRVLHGRMDPARHLA

Nucleotide

• Length: 294 bp

>T229919 NZ_CP124638:c2743225-2742647 [Pseudomonas aeruginosa]
ATGTCCCTCGAACTGCTGAGCAACCGCCTCGAATTCCTCCGCGAAGCCGAACGCCTGAAAGACGTCCTGCGCTCCGCGCA
CACCTCCTCCGGCCGCCCGGAAAGCACCGCCGAACATAGCTGGCGGCTTTGCCTGATGGCACTGGCCTTCGAGGACCAAC
TGGCCGGCCTGGACCTCGGCAAGGTTCTGCGCATGTGCGTGGTCCACGACCTCGGCGAAGCGATCCACGGCGACATCCCC
GCCGTCGAGCAAGCGGCGCACCCGGACAAGGGCGAACAGGAACGCGCCGACCTGTTGCAGCTGACCCGTCATCTGGACAC
GCCACTGCGCGATCGCCTGCTCGCCCTGTGGGACGAATACGAGCGCGGCGAGACCGCCGAAGCCCTGGCAGTGAAAGCGC
TGGACAAGCTGGAAACCCTGCTCCAGCACACCCAGGGCGATAATCCGGCGGACTTCGACTATGCCTTCAACCTCGACTAC
GGCCGTCGCTATACCGACCGCGCACCGCTGTTCAAGACCCTGCGCGAGCTACTCGACGCCAGGACCCGACAGCGCCTCGC
AGCTCGGCGCGACGCCTAG

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 10073.22 Da
• Isoelectric Point: 4.7064

>AT229919 WP_011910869.1 NZ_CP090023:c265106-264840 [Cereibacter azotoformans]
MSRLTISMPDQMNEWVEAQIAAGRYGNVSEYFRDLVRRDQERREAAVAELRTMLERADASGVSDRSFPDILEAARREARQ
KGLLGDEN

Nucleotide

• Length: 267 bp

>AT229919 NZ_CP124638:c2743867-2743313 [Pseudomonas aeruginosa]
ATGACCGAGCCTCTCCCTTCTTCGTCCCTGGGCCCCGCCCTGCGTCGCTGGCGCCTGCTGCACCGGGTCAAGCAAACGCA
TGCCGCCGAATTGCTCGGCGTGGCGCAATCGACCATCTCGCGCTGGGAGTCCGGTACCCAGGCGCTGCTGGTGGAGGAAC
GGGCACGCCTGGAGCGTCTGCTCGGCGCCCGCCTGGAAGCCGCCGCCGACCAGGCACTGGCCCGCCTGGTCGAAGCCAAC
CCGCAACCCGTGCACCTGATCTGCGACCTCACCCATCGCCTGTTGGCCTGTTCGCCGGCACGCGCCGCGCAATTCGGCGT
GCCTCTCGGCGAACTGCTCGACCGTTCGCTGTGGCCCTATTGCAGCGAGGAAATCCTCCGCCAGGAAGCCACCCTCGAGG
AACTCGGCTGGCGCGAACTGCTGGCACCGCCGGCGCTGGAGTTCGCCAGCGGAGCGAACGCCTCGGCCATCGTGCCGATC
CGGCGCAGCCGTTGCCGCTGGACCCGCATGACCCTCTCGGACGGACGCGCGGTGCGCCTGGTGGAAACCCTCTGA