Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 4151763..4152309 Replicon chromosome
Accession NZ_CP090005
Organism Providencia rettgeri strain PROV_UAMS_01

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LV777_RS18915 Protein ID WP_109912959.1
Coordinates 4152028..4152309 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LV777_RS18910 Protein ID WP_102140619.1
Coordinates 4151763..4152047 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LV777_RS18885 (LV777_18890) 4146838..4147815 - 978 WP_004265237.1 6-phosphofructokinase -
LV777_RS18890 (LV777_18895) 4148221..4149165 - 945 WP_109912960.1 phosphatidate cytidylyltransferase -
LV777_RS18895 (LV777_18900) 4149162..4149803 - 642 WP_110731554.1 lysophospholipid acyltransferase family protein -
LV777_RS18900 (LV777_18905) 4150041..4150793 - 753 WP_004907010.1 M48 family metallopeptidase -
LV777_RS18905 (LV777_18910) 4151020..4151601 - 582 WP_248445438.1 HutD family protein -
LV777_RS18910 (LV777_18915) 4151763..4152047 + 285 WP_102140619.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LV777_RS18915 (LV777_18920) 4152028..4152309 + 282 WP_109912959.1 type II toxin-antitoxin system YafQ family toxin Toxin
LV777_RS18920 (LV777_18925) 4152604..4153191 - 588 WP_164529273.1 Spy/CpxP family protein refolding chaperone -
LV777_RS18925 (LV777_18930) 4153342..4154040 + 699 WP_004907000.1 envelope stress response regulator transcription factor CpxR -
LV777_RS18930 (LV777_18935) 4154037..4155407 + 1371 WP_004906999.1 envelope stress sensor histidine kinase CpxA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-93)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(9-84)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10968.80 Da        Isoelectric Point: 9.1315

>T229913 WP_109912959.1 NZ_CP090005:4152028-4152309 [Providencia rettgeri]
MLKIRVKSQFKKDLKKSLSDKKRNTQLLKELIDNHLCITGSVPAEYLPHPLKGNWRPCYEYHIQPDFLLIWDINYQTNEI
ILVRCGSHSELFG

Download         Length: 282 bp

>T229913 NZ_CP124632:c6148353-6148054 [Pseudomonas aeruginosa]
ATGGTTGAAGTCAAACAAACCGCCACTTTCATGGCATGGGAAAGCAAGCTAAAGGATCGGCGGGCTAAGGCCGTGATCGC
CGCCCGTATCTTCCGATTGGCGAATGGACTACCCGGCGATGTGTCACCAGTCGGCCAGGGTGTGAGCGAGTTGAGGATTC
ACTATGGCCCAGGCTATCGGGTGTACTTCCAGCAGCGCGGGACGGAAATCGTCATTCTGCTATGTGGTGGAGACAAGAGC
AGCCAGGCCAGGGATATAGAAATGGCGAAACGCCTGGCAAATGAGTGGAGGCCGCAATGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10420.71 Da        Isoelectric Point: 4.6412

>AT229913 WP_102140619.1 NZ_CP090005:4151763-4152047 [Providencia rettgeri]
MASTQHKTDIVRARIEPKVRENAEAVLSELGISMSDAIRIFVKQISLRQAFPIELKTPNSITLEAINAPTTDETFDSAED
LFSQVSKSDAENSR

Download         Length: 285 bp

>AT229913 NZ_CP124632:c6148057-6147767 [Pseudomonas aeruginosa]
ATGACCGAGCAAATTTATGATTATGACCCCGCGCAAGCGCTGGACAGCCCGGAGGCCATGGCTCTGTTCATCGCAGACGC
TTTGGATACTGGAGACACCGCCTATATCGCTAAGGCTATGGGAGTCGTGGCCCGCGCCAAGGGGATGACGGAGTTGGCCA
AGGAAACGGGTTTGGCCAGGGAGCAGCTTTACAAATCGTTTAGTGAGCGCGGGAACCCTACATTGAAAACCATGCTGGCA
GTAATGCGAGCTCTGGGAGTTGATCTGACCGCCCGCCCGCATGCTCAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References