229897

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4411504..4411889 Replicon chromosome
Accession NZ_CP090000
Organism Xanthomonas translucens strain B1FA

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0K2ZHE5
Locus tag LZE81_RS18990 Protein ID WP_003469322.1
Coordinates 4411504..4411638 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A1C3TTT1
Locus tag LZE81_RS18995 Protein ID WP_003469323.1
Coordinates 4411737..4411889 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LZE81_RS18975 (LZE81_18975) 4407954..4408877 - 924 WP_060744653.1 MBL fold metallo-hydrolase -
LZE81_RS18980 (LZE81_18980) 4408933..4410333 - 1401 WP_060744654.1 tryptophan--tRNA ligase -
LZE81_RS18985 (LZE81_18985) 4410444..4411295 + 852 WP_060744655.1 hypothetical protein -
LZE81_RS18990 (LZE81_18990) 4411504..4411638 - 135 WP_003469322.1 entericidin A/B family lipoprotein Toxin
LZE81_RS18995 (LZE81_18995) 4411737..4411889 - 153 WP_003469323.1 entericidin A/B family lipoprotein Antitoxin
LZE81_RS19000 (LZE81_19000) 4412033..4412956 - 924 WP_058360588.1 arginase -
LZE81_RS19010 (LZE81_19010) 4413344..4414180 - 837 WP_161993387.1 SPOR domain-containing protein -
LZE81_RS19015 (LZE81_19015) 4414190..4414930 - 741 WP_004427869.1 type III pantothenate kinase -
LZE81_RS19020 (LZE81_19020) 4414927..4415922 - 996 WP_153476936.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
LZE81_RS19025 (LZE81_19025) 4416060..4416332 + 273 WP_003476582.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-39)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4604.40 Da        Isoelectric Point: 9.2977

>T229897 WP_003469322.1 NZ_CP090000:c4411638-4411504 [Xanthomonas translucens]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN

Download         Length: 135 bp

>T229897 NZ_CP124626:2539562-2539744 [Pseudomonas aeruginosa]
ATGCGGAGTAGGGAAGTGATTGATTTGCTGTTGGAGGATGGCTGGTATGAAGTGGCGGTGAAAGGTAGCCACCACCAGTT
CAAACATCCTTCAAAGCCTGGAAAGGTGACGGTTCAACATCCGTCCTCGACGATACCGAAAGGAACCCTGAACAACATAC
TGAAACAAGCCGGCCTCAAGTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5350.35 Da        Isoelectric Point: 8.1210

>AT229897 WP_003469323.1 NZ_CP090000:c4411889-4411737 [Xanthomonas translucens]
MKRLFTLTMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVETKADDCKDGKC

Download         Length: 153 bp

>AT229897 NZ_CP124626:2539772-2540176 [Pseudomonas aeruginosa]
ATGAAATTCCCCGTGGTGTTACACAAAGACCCTGATTCTGACTATGGCGTGACTGTGCCCGATGTGCCGGGTTGCTTCTC
TGCCGGCGCTACGGTGTCCGAGGCCCTGGCCAATGTAGAAGAGGCGCTGGCCTTGCACTTCGAAGGCTTGGTTACGGACG
GCGAAGAGCTACCCCAGCCGCAGGACGTTGACGCCCATATGAAGAATCCGGACTTCGAAGGTGGCGTATGGGCGGTGGTT
GACTTCGACGTGACCCCGTACCTGGGCAAGGCCGTACGCTTTAATGCGACGCTCCCGGAACACCTTCTGCAGCGGATCGA
TGAGCGCGTGAAGGTGGATAAGCGCTATCAGTCTCGGTCGGGCTTTCTGGCAACAGCGGCGATGCGCGAACTGTCAGTGG
CGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K2ZHE5

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TTT1

References