Detailed information of TA system TA229896

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): omega-epsilon-zeta/-
• Location: 4116168..4117734
• Replicon: chromosome
• Accession: NZ_CP090000
• Organism: Xanthomonas translucens strain B1FA

Toxin (Protein)

• Gene name: avrRxo1
• Uniprot ID: -
• Locus tag: LZE81_RS17725
• Protein ID: WP_003480647.1
• Coordinates: 4116168..4117424 (+)
• Length: 419 a.a.

Antitoxin (Protein)

• Gene name: arc1
• Uniprot ID: -
• Locus tag: LZE81_RS17730
• Protein ID: WP_003480646.1
• Coordinates: 4117438..4117734 (+)
• Length: 99 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LZE81_RS17715 (LZE81_17715)	4113479..4114420	-	942	WP_003465367.1	alpha-E domain-containing protein	-
LZE81_RS17720 (LZE81_17720)	4114420..4115868	-	1449	WP_003480648.1	circularly permuted type 2 ATP-grasp protein	-
LZE81_RS17725 (LZE81_17725)	4116168..4117424	+	1257	WP_003480647.1	XopAJ/AvrRxo1 family type III secretion system effector zeta toxin	Toxin
LZE81_RS17730 (LZE81_17730)	4117438..4117734	+	297	WP_003480646.1	hypothetical protein	Antitoxin
LZE81_RS17735 (LZE81_17735)	4118263..4118616	-	354	WP_003480645.1	dihydroneopterin aldolase	-
LZE81_RS17740 (LZE81_17740)	4118609..4119757	-	1149	WP_058360827.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	-
LZE81_RS17745 (LZE81_17745)	4119879..4120094	+	216	WP_003465342.1	30S ribosomal protein S21	-
LZE81_RS17750 (LZE81_17750)	4120374..4120823	+	450	WP_058360826.1	GatB/YqeY domain-containing protein	-
LZE81_RS17755 (LZE81_17755)	4120957..4121871	+	915	WP_003465336.1	YihY/virulence factor BrkB family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Zeta toxin domain (148-285)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 419 a.a.
• Molecular weight: 45042.67 Da
• Isoelectric Point: 6.6145

>T229896 WP_003480647.1 NZ_CP090000:4116168-4117424 [Xanthomonas translucens]
MKGKISNACKPDITPILVDGLASTATQGAADDSASRLPQQALLDGLQERPQALKKSNSADWSARTLPQWAPGPGTSSKAL
LIQSPPHPTSSDEMFGLGELPAPGKARWEYLTKTENWHPERQELHSRLLSQARTASLRLAESIESDGYPPTLFALRGNTA
TGKTRIATKTIPVLANALKKSSGGGCINPDIFKRSLAESQGEAMKLSSAQVHAESCVLADRLENELRSQRTTSGAMASIL
VDKRLANTHEVDSYVSLAKETGRKVELCDIDAPLERSLMGVLQRSPGGDDPRPPYVAVANGFSTVRSNRLDVIDRFLSNP
TLGSYRLFGTNEKGEKVMVASVADGELSIHDPQLYESITAPEDFNSGDKGEQVIDTALIDRLSNSIDDPKRATDARAALE
KYKGMTWSNALAAHSSLI

Nucleotide

• Length: 1257 bp

>T229896 NZ_CP124626:2420450-2420740 [Pseudomonas aeruginosa]
ATGACCGAGCAAATTTATGATTATGACCCCGCGCAAGCGCTGGACAGCCCGGAGGCCATGGCTCTGTTCATCGCAGACGC
TTTGGATACTGGAGACACCGCCTATATCGCTAAGGCTATGGGAGTCGTGGCCCGCGCCAAGGGGATGACGGAGTTGGCCA
AGGAAACGGGTTTGGCCAGGGAGCAGCTTTACAAATCGTTTAGTGAGCGCGGGAACCCTACATTGAAAACCATGCTGGCA
GTAATGCGAGCTCTGGGAGTTGATCTGACCGCCCGCCCGCATGCTCAGTGA

Antitoxin

Protein

• Length: 99 a.a.
• Molecular weight: 11088.54 Da
• Isoelectric Point: 7.3576

>AT229896 WP_003480646.1 NZ_CP090000:4117438-4117734 [Xanthomonas translucens]
MTHLKGADALALHKKLKERNASLRSAELDSAKALAHESGKERFNLEKLESICDTTQAGRITDPNDRQAIYEQMYYVEHPK
VSTLQEFARIVVTISSWS

Nucleotide

• Length: 297 bp

>AT229896 NZ_CP124626:2420154-2420453 [Pseudomonas aeruginosa]
ATGGTTGAAGTCAAACAAACCGCCACTTTCATGGCATGGGAAAGCAAGCTAAAGGATCGGCGGGCTAAGGCCGTGATCGC
CGCCCGTATCTTCCGATTGGCGAATGGACTACCCGGCGATGTGTCACCAGTCGGCCAGGGTGTGAGCGAGTTGAGGATTC
ACTATGGCCCAGGCTATCGGGTGTACTTCCAGCAGCGCGGGACGGAAATCGTCATTCTGCTATGTGGTGGAGACAAGAGC
AGCCAGGCCAGGGATATAGAAATGGCGAAACGCCTGGCAAATGAGTGGAGGCCGCAATGA