Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-StbC |
| Location | 2276973..2277643 | Replicon | chromosome |
| Accession | NZ_CP090000 | ||
| Organism | Xanthomonas translucens strain B1FA | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | LZE81_RS09790 | Protein ID | WP_058361064.1 |
| Coordinates | 2277224..2277643 (+) | Length | 140 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | A0A2S7EM03 |
| Locus tag | LZE81_RS09785 | Protein ID | WP_003473422.1 |
| Coordinates | 2276973..2277227 (+) | Length | 85 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LZE81_RS09765 (LZE81_09765) | 2272510..2273475 | - | 966 | Protein_1914 | IS1595 family transposase | - |
| LZE81_RS09770 (LZE81_09770) | 2273992..2275127 | + | 1136 | WP_153476785.1 | IS3 family transposase | - |
| LZE81_RS09775 (LZE81_09775) | 2275163..2275663 | + | 501 | Protein_1916 | replication protein C, IncQ-type | - |
| LZE81_RS09780 (LZE81_09780) | 2276280..2276561 | + | 282 | WP_058361065.1 | TraK family protein | - |
| LZE81_RS09785 (LZE81_09785) | 2276973..2277227 | + | 255 | WP_003473422.1 | hypothetical protein | Antitoxin |
| LZE81_RS09790 (LZE81_09790) | 2277224..2277643 | + | 420 | WP_058361064.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| LZE81_RS09795 (LZE81_09795) | 2277800..2278570 | + | 771 | WP_058361066.1 | P-type conjugative transfer protein TrbJ | - |
| LZE81_RS09800 (LZE81_09800) | 2278581..2278739 | + | 159 | WP_153476784.1 | hypothetical protein | - |
| LZE81_RS09805 (LZE81_09805) | 2278741..2280141 | + | 1401 | WP_058361063.1 | P-type conjugative transfer protein TrbL | - |
| LZE81_RS09810 (LZE81_09810) | 2280255..2280497 | + | 243 | WP_033981742.1 | type I toxin-antitoxin system ptaRNA1 family toxin | - |
| LZE81_RS09815 (LZE81_09815) | 2280509..2280793 | + | 285 | WP_058361062.1 | hypothetical protein | - |
| LZE81_RS09820 (LZE81_09820) | 2280796..2281164 | + | 369 | WP_058361061.1 | conjugal transfer transcriptional regulator TraJ | - |
| LZE81_RS09825 (LZE81_09825) | 2281132..2281521 | - | 390 | Protein_1926 | replication protein C, IncQ-type | - |
| LZE81_RS09830 (LZE81_09830) | 2281493..2282371 | - | 879 | WP_058361060.1 | helicase RepA family protein | - |
| LZE81_RS09835 (LZE81_09835) | 2282375..2282608 | - | 234 | WP_003472509.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 2272054..2291778 | 19724 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 140 a.a. Molecular weight: 14945.19 Da Isoelectric Point: 4.9167
>T229895 WP_058361064.1 NZ_CP090000:2277224-2277643 [Xanthomonas translucens]
MIVLDTNVVSEAMKPEPDPAVRAWLNEQVAETLYLSSVTLAELLFGIGALPNGKRKKGLGEALDGLLELFSERVLMFDTE
AARNYAELAVKARIAGKGFPTPDGYIGAIAASKGFIVATRDTSPFEAAGLTVINPWNHR
MIVLDTNVVSEAMKPEPDPAVRAWLNEQVAETLYLSSVTLAELLFGIGALPNGKRKKGLGEALDGLLELFSERVLMFDTE
AARNYAELAVKARIAGKGFPTPDGYIGAIAASKGFIVATRDTSPFEAAGLTVINPWNHR
Download Length: 420 bp
>T229895 NZ_CP124626:2420154-2420453 [Pseudomonas aeruginosa]
ATGGTTGAAGTCAAACAAACCGCCACTTTCATGGCATGGGAAAGCAAGCTAAAGGATCGGCGGGCTAAGGCCGTGATCGC
CGCCCGTATCTTCCGATTGGCGAATGGACTACCCGGCGATGTGTCACCAGTCGGCCAGGGTGTGAGCGAGTTGAGGATTC
ACTATGGCCCAGGCTATCGGGTGTACTTCCAGCAGCGCGGGACGGAAATCGTCATTCTGCTATGTGGTGGAGACAAGAGC
AGCCAGGCCAGGGATATAGAAATGGCGAAACGCCTGGCAAATGAGTGGAGGCCGCAATGA
ATGGTTGAAGTCAAACAAACCGCCACTTTCATGGCATGGGAAAGCAAGCTAAAGGATCGGCGGGCTAAGGCCGTGATCGC
CGCCCGTATCTTCCGATTGGCGAATGGACTACCCGGCGATGTGTCACCAGTCGGCCAGGGTGTGAGCGAGTTGAGGATTC
ACTATGGCCCAGGCTATCGGGTGTACTTCCAGCAGCGCGGGACGGAAATCGTCATTCTGCTATGTGGTGGAGACAAGAGC
AGCCAGGCCAGGGATATAGAAATGGCGAAACGCCTGGCAAATGAGTGGAGGCCGCAATGA
Antitoxin
Download Length: 85 a.a. Molecular weight: 9507.88 Da Isoelectric Point: 7.2071
>AT229895 WP_003473422.1 NZ_CP090000:2276973-2277227 [Xanthomonas translucens]
MAILTVRNVPDEVHRALRLRAAEHGRSTEAEVREILESAVKSQKRIRMGDALAELGRRVGLTNDDFAVLDQVRDKVPAEP
MRFE
MAILTVRNVPDEVHRALRLRAAEHGRSTEAEVREILESAVKSQKRIRMGDALAELGRRVGLTNDDFAVLDQVRDKVPAEP
MRFE
Download Length: 255 bp
>AT229895 NZ_CP124626:2420450-2420740 [Pseudomonas aeruginosa]
ATGACCGAGCAAATTTATGATTATGACCCCGCGCAAGCGCTGGACAGCCCGGAGGCCATGGCTCTGTTCATCGCAGACGC
TTTGGATACTGGAGACACCGCCTATATCGCTAAGGCTATGGGAGTCGTGGCCCGCGCCAAGGGGATGACGGAGTTGGCCA
AGGAAACGGGTTTGGCCAGGGAGCAGCTTTACAAATCGTTTAGTGAGCGCGGGAACCCTACATTGAAAACCATGCTGGCA
GTAATGCGAGCTCTGGGAGTTGATCTGACCGCCCGCCCGCATGCTCAGTGA
ATGACCGAGCAAATTTATGATTATGACCCCGCGCAAGCGCTGGACAGCCCGGAGGCCATGGCTCTGTTCATCGCAGACGC
TTTGGATACTGGAGACACCGCCTATATCGCTAAGGCTATGGGAGTCGTGGCCCGCGCCAAGGGGATGACGGAGTTGGCCA
AGGAAACGGGTTTGGCCAGGGAGCAGCTTTACAAATCGTTTAGTGAGCGCGGGAACCCTACATTGAAAACCATGCTGGCA
GTAATGCGAGCTCTGGGAGTTGATCTGACCGCCCGCCCGCATGCTCAGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|