Detailed information of TA system TA229893

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YoeB-YefM
• Location: 1072469..1072974
• Replicon: chromosome
• Accession: NZ_CP090000
• Organism: Xanthomonas translucens strain B1FA

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: LZE81_RS04900
• Protein ID: WP_058195736.1
• Coordinates: 1072469..1072726 (-)
• Length: 86 a.a.

Antitoxin (Protein)

• Gene name: relE
• Uniprot ID: A0A1C3TRJ9
• Locus tag: LZE81_RS04905
• Protein ID: WP_003468816.1
• Coordinates: 1072723..1072974 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LZE81_RS04870 (LZE81_04870)	1067703..1069052	+	1350	WP_058360629.1	aminodeoxychorismate synthase component I	-
LZE81_RS04875 (LZE81_04875)	1069128..1070189	+	1062	WP_058360633.1	endolytic transglycosylase MltG	-
LZE81_RS04880 (LZE81_04880)	1070186..1070854	+	669	WP_003479795.1	dTMP kinase	-
LZE81_RS04885 (LZE81_04885)	1070851..1071828	+	978	WP_003479796.1	DNA polymerase III subunit delta'	-
LZE81_RS04890 (LZE81_04890)	1071825..1072178	+	354	WP_003479797.1	PilZ domain-containing protein	-
LZE81_RS04900 (LZE81_04900)	1072469..1072726	-	258	WP_058195736.1	Txe/YoeB family addiction module toxin	Toxin
LZE81_RS04905 (LZE81_04905)	1072723..1072974	-	252	WP_003468816.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
LZE81_RS04910 (LZE81_04910)	1073083..1073616	+	534	Protein_958	endonuclease	-
LZE81_RS04915 (LZE81_04915)	1073613..1074335	-	723	WP_058360631.1	helix-turn-helix transcriptional regulator	-
LZE81_RS04920 (LZE81_04920)	1074459..1074902	+	444	WP_058360632.1	nuclear transport factor 2 family protein	-
LZE81_RS04925 (LZE81_04925)	1075072..1075221	+	150	WP_230939940.1	type II toxin-antitoxin system RelE/ParE family toxin	-
LZE81_RS04930 (LZE81_04930)	1075341..1075523	+	183	WP_196480047.1	hypothetical protein	-
LZE81_RS20010	1076371..1076493	+	123	WP_267919419.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	1075498..1075896	398

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (2-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 86 a.a.
• Molecular weight: 10216.73 Da
• Isoelectric Point: 9.7381

>T229893 WP_058195736.1 NZ_CP090000:c1072726-1072469 [Xanthomonas translucens]
VTLQFSDNAWEDDLYWQQTDKKMLKRINDLIKAIQRDPFQGVGKPERLRHALAGYWSRRINDEHRIVYKVEAGMLLIAQV
RYHYV

Nucleotide

• Length: 258 bp

>T229893 NZ_CP124626:799422-799703 [Pseudomonas aeruginosa]
ATGAGCCTGAAGTGGACCCGCAAGGCGGCCGCCGACCTGGACGCCATCTACGACCATTACGTCGTGCTGATCGGCCCGGA
AAAAGCCCTGAAAGCCGTCCAGGACATCGTCGAGCAGGTGAAACCGCTGCAGCAGGTAGCCAACCAGGGGGCAGGGCGGC
CCAGCGAGGTGCCAGGCGTACGCACCCTGACCCTGGAGCGCTGGCCGTTCAGCGCCCCTTTTCGGGTAAAAGGCAAGGAA
ATCCAGATTTTGCGCATCGACAGGGTCGAAATTACCCCCTAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9281.56 Da
• Isoelectric Point: 5.1186

>AT229893 WP_003468816.1 NZ_CP090000:c1072974-1072723 [Xanthomonas translucens]
MDTITYSAARAALADTMERVVNNHEPVIITRSREQSVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKARD
LAE

Nucleotide

• Length: 252 bp

>AT229893 NZ_CP124626:799198-799425 [Pseudomonas aeruginosa]
ATGAGCACCGTAGTCTCGTTCCGCGCCGATGACGCCCTGGTCGCGGCCCTCGACGAACTGGCCCGCGCCACCCACCGCGA
CCGCCCGTATCACCTGCGGCAGGCGCTCGCGCAGTACCTGGAAAGGCAGCAGTGGCAGGTCGCTGCCATCGATGAAGGCT
TGGCCGATGCCAATGCCGGTCGCCTGCTGGAACACACCGAGATCGAGAAGCGCTGGGGGCTGCAATGA

Structures

Antitoxin

• AlphaFold DB: A0A1C3TRJ9