Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4450244..4450629 Replicon chromosome
Accession NZ_CP089999
Organism Xanthomonas translucens strain B8GF

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0K2ZHE5
Locus tag LV507_RS19350 Protein ID WP_003469322.1
Coordinates 4450244..4450378 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A1C3TTT1
Locus tag LV507_RS19355 Protein ID WP_003469323.1
Coordinates 4450477..4450629 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LV507_RS19335 (LV507_19335) 4446694..4447617 - 924 WP_064521685.1 MBL fold metallo-hydrolase -
LV507_RS19340 (LV507_19340) 4447673..4449073 - 1401 WP_060744654.1 tryptophan--tRNA ligase -
LV507_RS19345 (LV507_19345) 4449184..4450035 + 852 WP_060744655.1 hypothetical protein -
LV507_RS19350 (LV507_19350) 4450244..4450378 - 135 WP_003469322.1 entericidin A/B family lipoprotein Toxin
LV507_RS19355 (LV507_19355) 4450477..4450629 - 153 WP_003469323.1 entericidin A/B family lipoprotein Antitoxin
LV507_RS19360 (LV507_19360) 4450773..4451696 - 924 WP_058360588.1 arginase -
LV507_RS19370 (LV507_19370) 4452084..4452920 - 837 WP_161993387.1 SPOR domain-containing protein -
LV507_RS19375 (LV507_19375) 4452930..4453670 - 741 WP_004427869.1 type III pantothenate kinase -
LV507_RS19380 (LV507_19380) 4453667..4454662 - 996 WP_153476936.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
LV507_RS19385 (LV507_19385) 4454800..4455072 + 273 WP_003476582.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-39)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4604.40 Da        Isoelectric Point: 9.2977

>T229892 WP_003469322.1 NZ_CP089999:c4450378-4450244 [Xanthomonas translucens]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN

Download         Length: 135 bp

>T229892 NZ_CP124624:c6054748-6054458 [Pseudomonas aeruginosa]
ATGTACTCCATTATCGAAACCGAGGCGTTCAGCGACTGGCTGAACGGCCTGAAAGATACGGTCACCCGCATGCGCTTGAT
CAAGCGTTTGCAGCGCGCAAGCCTGGGCAACCTGGGCGATGTGAAGCCGGTTGGTGAAGGGGTGTATGAAATGCGCGAGT
TTTTCGGCCCTGGCTGGCGCATGTACTACGTGCAGCAGGGCGATGTGCTGCTGATCATGCTGGGCGGTGGCGACAAATCC
AGCCAGCAGCGTGATATCGAGCGGGCAATTCAGTTGTCCAAGGAGCTCTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5350.35 Da        Isoelectric Point: 8.1210

>AT229892 WP_003469323.1 NZ_CP089999:c4450629-4450477 [Xanthomonas translucens]
MKRLFTLTMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVETKADDCKDGKC

Download         Length: 153 bp

>AT229892 NZ_CP124624:c6054457-6054164 [Pseudomonas aeruginosa]
ATGAACAAGACCAAGCTGAACATGCGGCCCTTCGATGCGGCCCACTACTTGAACAATGAGGAAGAGATGGCCGCCTACCT
CGACGTGATTCTGGAAGACAACGACCCGGCGCTGCTGGCCGTTGCTCTGGGCGATATCGCCCGTGCACGCGGCATGACCG
AGCTGGCCCGTAAAACCGGCCTGTCGCGTGAGAGCCTGTACAAGAGCCTGTCCGGCGAGCGCGTGCCGAGCACTGAAACG
CTGCTGAAGGTCATTCATGCCCTGGGCTTCAAGCTGACGGTCTCCGCCGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K2ZHE5

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TTT1

References