Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | EcnAB/- |
Location | 4450244..4450629 | Replicon | chromosome |
Accession | NZ_CP089999 | ||
Organism | Xanthomonas translucens strain B8GF |
Toxin (Protein)
Gene name | EcnB | Uniprot ID | A0A0K2ZHE5 |
Locus tag | LV507_RS19350 | Protein ID | WP_003469322.1 |
Coordinates | 4450244..4450378 (-) | Length | 45 a.a. |
Antitoxin (Protein)
Gene name | EcnA | Uniprot ID | A0A1C3TTT1 |
Locus tag | LV507_RS19355 | Protein ID | WP_003469323.1 |
Coordinates | 4450477..4450629 (-) | Length | 51 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LV507_RS19335 (LV507_19335) | 4446694..4447617 | - | 924 | WP_064521685.1 | MBL fold metallo-hydrolase | - |
LV507_RS19340 (LV507_19340) | 4447673..4449073 | - | 1401 | WP_060744654.1 | tryptophan--tRNA ligase | - |
LV507_RS19345 (LV507_19345) | 4449184..4450035 | + | 852 | WP_060744655.1 | hypothetical protein | - |
LV507_RS19350 (LV507_19350) | 4450244..4450378 | - | 135 | WP_003469322.1 | entericidin A/B family lipoprotein | Toxin |
LV507_RS19355 (LV507_19355) | 4450477..4450629 | - | 153 | WP_003469323.1 | entericidin A/B family lipoprotein | Antitoxin |
LV507_RS19360 (LV507_19360) | 4450773..4451696 | - | 924 | WP_058360588.1 | arginase | - |
LV507_RS19370 (LV507_19370) | 4452084..4452920 | - | 837 | WP_161993387.1 | SPOR domain-containing protein | - |
LV507_RS19375 (LV507_19375) | 4452930..4453670 | - | 741 | WP_004427869.1 | type III pantothenate kinase | - |
LV507_RS19380 (LV507_19380) | 4453667..4454662 | - | 996 | WP_153476936.1 | bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA | - |
LV507_RS19385 (LV507_19385) | 4454800..4455072 | + | 273 | WP_003476582.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 45 a.a. Molecular weight: 4604.40 Da Isoelectric Point: 9.2977
>T229892 WP_003469322.1 NZ_CP089999:c4450378-4450244 [Xanthomonas translucens]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN
Download Length: 135 bp
>T229892 NZ_CP124624:c6054748-6054458 [Pseudomonas aeruginosa]
ATGTACTCCATTATCGAAACCGAGGCGTTCAGCGACTGGCTGAACGGCCTGAAAGATACGGTCACCCGCATGCGCTTGAT
CAAGCGTTTGCAGCGCGCAAGCCTGGGCAACCTGGGCGATGTGAAGCCGGTTGGTGAAGGGGTGTATGAAATGCGCGAGT
TTTTCGGCCCTGGCTGGCGCATGTACTACGTGCAGCAGGGCGATGTGCTGCTGATCATGCTGGGCGGTGGCGACAAATCC
AGCCAGCAGCGTGATATCGAGCGGGCAATTCAGTTGTCCAAGGAGCTCTGA
ATGTACTCCATTATCGAAACCGAGGCGTTCAGCGACTGGCTGAACGGCCTGAAAGATACGGTCACCCGCATGCGCTTGAT
CAAGCGTTTGCAGCGCGCAAGCCTGGGCAACCTGGGCGATGTGAAGCCGGTTGGTGAAGGGGTGTATGAAATGCGCGAGT
TTTTCGGCCCTGGCTGGCGCATGTACTACGTGCAGCAGGGCGATGTGCTGCTGATCATGCTGGGCGGTGGCGACAAATCC
AGCCAGCAGCGTGATATCGAGCGGGCAATTCAGTTGTCCAAGGAGCTCTGA
Antitoxin
Download Length: 51 a.a. Molecular weight: 5350.35 Da Isoelectric Point: 8.1210
>AT229892 WP_003469323.1 NZ_CP089999:c4450629-4450477 [Xanthomonas translucens]
MKRLFTLTMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVETKADDCKDGKC
MKRLFTLTMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVETKADDCKDGKC
Download Length: 153 bp
>AT229892 NZ_CP124624:c6054457-6054164 [Pseudomonas aeruginosa]
ATGAACAAGACCAAGCTGAACATGCGGCCCTTCGATGCGGCCCACTACTTGAACAATGAGGAAGAGATGGCCGCCTACCT
CGACGTGATTCTGGAAGACAACGACCCGGCGCTGCTGGCCGTTGCTCTGGGCGATATCGCCCGTGCACGCGGCATGACCG
AGCTGGCCCGTAAAACCGGCCTGTCGCGTGAGAGCCTGTACAAGAGCCTGTCCGGCGAGCGCGTGCCGAGCACTGAAACG
CTGCTGAAGGTCATTCATGCCCTGGGCTTCAAGCTGACGGTCTCCGCCGCTTGA
ATGAACAAGACCAAGCTGAACATGCGGCCCTTCGATGCGGCCCACTACTTGAACAATGAGGAAGAGATGGCCGCCTACCT
CGACGTGATTCTGGAAGACAACGACCCGGCGCTGCTGGCCGTTGCTCTGGGCGATATCGCCCGTGCACGCGGCATGACCG
AGCTGGCCCGTAAAACCGGCCTGTCGCGTGAGAGCCTGTACAAGAGCCTGTCCGGCGAGCGCGTGCCGAGCACTGAAACG
CTGCTGAAGGTCATTCATGCCCTGGGCTTCAAGCTGACGGTCTCCGCCGCTTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0K2ZHE5 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1C3TTT1 |