Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 3660114..3660619 Replicon chromosome
Accession NZ_CP089999
Organism Xanthomonas translucens strain B8GF

Toxin (Protein)


Gene name relE Uniprot ID A0A1C3TRG2
Locus tag LV507_RS16025 Protein ID WP_003479798.1
Coordinates 3660362..3660619 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID A0A1C3TRJ9
Locus tag LV507_RS16020 Protein ID WP_003468816.1
Coordinates 3660114..3660365 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LV507_RS15995 (LV507_15995) 3655185..3656420 + 1236 WP_065899003.1 citrate synthase family protein -
LV507_RS16000 (LV507_16000) 3657122..3658141 + 1020 WP_229017866.1 hypothetical protein -
LV507_RS16005 (LV507_16005) 3658177..3658620 - 444 WP_003479801.1 nuclear transport factor 2 family protein -
LV507_RS16010 (LV507_16010) 3658742..3659464 + 723 WP_003479800.1 helix-turn-helix transcriptional regulator -
LV507_RS16015 (LV507_16015) 3659461..3660005 - 545 Protein_3156 endonuclease -
LV507_RS16020 (LV507_16020) 3660114..3660365 + 252 WP_003468816.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LV507_RS16025 (LV507_16025) 3660362..3660619 + 258 WP_003479798.1 Txe/YoeB family addiction module toxin Toxin
LV507_RS16035 (LV507_16035) 3661254..3661607 - 354 WP_003479797.1 PilZ domain-containing protein -
LV507_RS16040 (LV507_16040) 3661604..3662581 - 978 WP_003479796.1 DNA polymerase III subunit delta' -
LV507_RS16045 (LV507_16045) 3662578..3663246 - 669 WP_003479795.1 dTMP kinase -
LV507_RS16050 (LV507_16050) 3663243..3664310 - 1068 WP_172837969.1 endolytic transglycosylase MltG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10156.61 Da        Isoelectric Point: 9.7381

>T229890 WP_003479798.1 NZ_CP089999:3660362-3660619 [Xanthomonas translucens]
VTLQFSDNAWEDDLYWQQTDKKMLKRINDLIKAIQRDPFQGVGKPERLRHALAGYWSRRINDEHRIVYKVEAGVLLIAQV
RYHYA

Download         Length: 258 bp

>T229890 NZ_CP124624:c5441903-5441625 [Pseudomonas aeruginosa]
ATGATTCTGACCTTTCGCTGCGACGAGACTCGTCAGCTTTTTGAGACGGGTCTTTCGAGGCGGTGGGGAGCGATCCTCAC
AGTCGCTACGCGTAAGCTCGCAATGCTTCATGCGGCTACGGAGCTTCGAGACTTGCGCTCTCCACCTGGAAACCGCTTGG
AGCCGTTGCAGGGAAAGCGGGCGGGCCAACATAGCATCAGGATCAATGACCAGTGGCGTGTCTGTTTCGTCTGGACGGAT
GCGGGTCCCGAAGAAGTCGAAATAGTTGATTACCACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9281.56 Da        Isoelectric Point: 5.1186

>AT229890 WP_003468816.1 NZ_CP089999:3660114-3660365 [Xanthomonas translucens]
MDTITYSAARAALADTMERVVNNHEPVIITRSREQSVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKARD
LAE

Download         Length: 252 bp

>AT229890 NZ_CP124624:c5441613-5441308 [Pseudomonas aeruginosa]
ATGGCTACCAATGGTATGCGCCCCATCCATCCTGGGGAAATATTGCGCGATGAGTTTCTGATGGAGTTGGATATCTCTCC
AGCTGCTCTAGCACGCGCTTTGAAAGTCTCCGCTCCGACAGTGAACGATATCGTTCGTGAGCAGCGTGGTATCTCCGCAG
ATATGGCGATTCGTCTGGGGCGTTACTTTGATACGTCCGCTCAGTTCTGGATGAATCTCCAGAGTGAGTACTCGTTAGCA
ACTGCTTATGCGGCGAATGGCGAGCAGATCGAACATGAGATTGAGCCGCTGCTTGCTCAGGGATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1C3TRG2

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TRJ9

References