Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4112974..4113119 Replicon chromosome
Accession NZ_CP089989
Organism Klebsiella pneumoniae strain LZKP00003

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4113010..4113112 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4112974..4113119 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LUR00_RS19680 (LUR00_19680) 4108104..4110164 + 2061 WP_004148850.1 oligopeptidase B -
LUR00_RS19685 (LUR00_19685) 4110168..4110827 - 660 WP_032435029.1 exodeoxyribonuclease X -
LUR00_RS19690 (LUR00_19690) 4110906..4111136 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LUR00_RS19695 (LUR00_19695) 4111249..4111623 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LUR00_RS19700 (LUR00_19700) 4111627..4112496 + 870 WP_032435031.1 copper homeostasis membrane protein CopD -
LUR00_RS19705 (LUR00_19705) 4112513..4112851 + 339 WP_180812522.1 YebY family protein -
- 4112974..4113119 - 146 - - Antitoxin
- 4113010..4113112 + 103 - - Toxin
LUR00_RS19710 (LUR00_19710) 4113487..4113630 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LUR00_RS19715 (LUR00_19715) 4113735..4114703 - 969 WP_004151446.1 VirK/YbjX family protein -
LUR00_RS19720 (LUR00_19720) 4114860..4115513 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
LUR00_RS19725 (LUR00_19725) 4115510..4115701 - 192 WP_002911395.1 YebW family protein -
LUR00_RS19730 (LUR00_19730) 4115799..4116038 - 240 WP_002911393.1 YebV family protein -
LUR00_RS19735 (LUR00_19735) 4116154..4117587 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T229871 NZ_CP089989:4113010-4113112 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT229871 NZ_CP089989:c4113119-4112974 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References