Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | tacAT/DUF1778(antitoxin) |
| Location | 1940782..1941587 | Replicon | chromosome |
| Accession | NC_011060 | ||
| Organism | Pelodictyon phaeoclathratiforme BU-1 | ||
Toxin (Protein)
| Gene name | TacT3 | Uniprot ID | B4SBL7 |
| Locus tag | PPHA_RS09115 | Protein ID | WP_012508555.1 |
| Coordinates | 1940782..1941312 (-) | Length | 177 a.a. |
Antitoxin (Protein)
| Gene name | TacA3 | Uniprot ID | - |
| Locus tag | PPHA_RS09120 | Protein ID | WP_012508556.1 |
| Coordinates | 1941309..1941587 (-) | Length | 93 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PPHA_RS09085 | 1936491..1937534 | + | 1044 | WP_012508548.1 | succinylglutamate desuccinylase/aspartoacylase family protein | - |
| PPHA_RS15135 | 1937612..1937740 | - | 129 | Protein_1782 | type II toxin-antitoxin system MqsA family antitoxin | - |
| PPHA_RS09095 | 1937905..1938795 | - | 891 | WP_012508550.1 | methyltransferase domain-containing protein | - |
| PPHA_RS09100 | 1938846..1939277 | - | 432 | WP_012508551.1 | thiol-disulfide oxidoreductase DCC family protein | - |
| PPHA_RS09105 | 1939899..1940294 | - | 396 | WP_012508553.1 | type II toxin-antitoxin system MqsA family antitoxin | - |
| PPHA_RS09110 | 1940307..1940615 | - | 309 | WP_012508554.1 | type II toxin-antitoxin system MqsR family toxin | - |
| PPHA_RS09115 | 1940782..1941312 | - | 531 | WP_012508555.1 | hypothetical protein | Toxin |
| PPHA_RS09120 | 1941309..1941587 | - | 279 | WP_012508556.1 | DUF1778 domain-containing protein | Antitoxin |
| PPHA_RS09125 | 1941786..1942166 | + | 381 | WP_012508557.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| PPHA_RS09130 | 1942153..1942476 | + | 324 | WP_041526503.1 | DNA-binding transcriptional regulator | - |
| PPHA_RS09135 | 1942745..1943101 | - | 357 | WP_012508559.1 | DNA-binding protein | - |
| PPHA_RS15140 | 1943111..1943197 | - | 87 | WP_083765320.1 | type II toxin-antitoxin system HigB family toxin | - |
| PPHA_RS09140 | 1943194..1943595 | - | 402 | WP_190273982.1 | TIGR02646 family protein | - |
| PPHA_RS09145 | 1943643..1944914 | - | 1272 | WP_049759920.1 | AAA family ATPase | - |
| PPHA_RS09150 | 1945165..1945647 | - | 483 | WP_012508562.1 | helix-turn-helix domain-containing protein | - |
| PPHA_RS09155 | 1945652..1946107 | - | 456 | WP_012508563.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 177 a.a. Molecular weight: 19239.43 Da Isoelectric Point: 10.0046
>T22987 WP_012508555.1 NC_011060:c1941312-1940782 [Pelodictyon phaeoclathratiforme BU-1]
MTLPAWHEEPITKSHDRRFAFDCGDEALNEFLWRHARKTHISGGAKTFLAVENSDVRKILGFYSIAPASVTYEKTPEVIK
RGLARHEVPVFRLGRLAVDRSVPGRSMGGQLLLAVARRCLLVAAQVGGVALLIDAKNDLVAQWYASYGAVPLLDAPLSLL
LPFKTIHAALVSAGKL
MTLPAWHEEPITKSHDRRFAFDCGDEALNEFLWRHARKTHISGGAKTFLAVENSDVRKILGFYSIAPASVTYEKTPEVIK
RGLARHEVPVFRLGRLAVDRSVPGRSMGGQLLLAVARRCLLVAAQVGGVALLIDAKNDLVAQWYASYGAVPLLDAPLSLL
LPFKTIHAALVSAGKL
Download Length: 531 bp
>T22987 NC_011060:c1941312-1940782 [Pelodictyon phaeoclathratiforme BU-1]
ATGACTCTTCCTGCCTGGCACGAAGAGCCGATCACCAAAAGCCATGACCGCCGGTTTGCTTTTGATTGCGGGGATGAAGC
CTTGAATGAGTTTTTGTGGCGTCATGCCAGAAAAACTCATATCAGTGGCGGGGCCAAAACTTTTCTGGCAGTGGAAAATA
GTGACGTCAGGAAGATTCTCGGCTTTTACAGTATAGCCCCGGCGTCTGTTACCTATGAGAAAACTCCGGAAGTGATCAAA
CGAGGATTAGCCCGCCATGAGGTGCCGGTCTTCAGGCTTGGTCGTTTAGCAGTTGACCGATCTGTTCCGGGCCGCAGTAT
GGGTGGGCAGTTATTGCTTGCTGTCGCTCGTCGTTGCTTGCTTGTTGCTGCACAGGTTGGCGGTGTTGCTCTTCTCATCG
ATGCGAAGAATGATCTGGTTGCACAGTGGTATGCCAGCTATGGGGCAGTGCCGTTGCTTGATGCACCGCTTTCACTTCTT
TTGCCGTTCAAAACTATCCATGCGGCCCTTGTTTCAGCAGGGAAACTTTGA
ATGACTCTTCCTGCCTGGCACGAAGAGCCGATCACCAAAAGCCATGACCGCCGGTTTGCTTTTGATTGCGGGGATGAAGC
CTTGAATGAGTTTTTGTGGCGTCATGCCAGAAAAACTCATATCAGTGGCGGGGCCAAAACTTTTCTGGCAGTGGAAAATA
GTGACGTCAGGAAGATTCTCGGCTTTTACAGTATAGCCCCGGCGTCTGTTACCTATGAGAAAACTCCGGAAGTGATCAAA
CGAGGATTAGCCCGCCATGAGGTGCCGGTCTTCAGGCTTGGTCGTTTAGCAGTTGACCGATCTGTTCCGGGCCGCAGTAT
GGGTGGGCAGTTATTGCTTGCTGTCGCTCGTCGTTGCTTGCTTGTTGCTGCACAGGTTGGCGGTGTTGCTCTTCTCATCG
ATGCGAAGAATGATCTGGTTGCACAGTGGTATGCCAGCTATGGGGCAGTGCCGTTGCTTGATGCACCGCTTTCACTTCTT
TTGCCGTTCAAAACTATCCATGCGGCCCTTGTTTCAGCAGGGAAACTTTGA
Antitoxin
Download Length: 93 a.a. Molecular weight: 10270.01 Da Isoelectric Point: 9.9218
>AT22987 WP_012508556.1 NC_011060:c1941587-1941309 [Pelodictyon phaeoclathratiforme BU-1]
MPQIPVEGNERLSLRIASEEKSLLMRAAAIQNTHLTEFVTRTVVSAAQKVIDQYELIELTGRDRVHVLKLLEDPPLPNAK
LMAAARALPKRS
MPQIPVEGNERLSLRIASEEKSLLMRAAAIQNTHLTEFVTRTVVSAAQKVIDQYELIELTGRDRVHVLKLLEDPPLPNAK
LMAAARALPKRS
Download Length: 279 bp
>AT22987 NC_011060:c1941587-1941309 [Pelodictyon phaeoclathratiforme BU-1]
ATGCCACAGATTCCGGTAGAAGGTAACGAGAGGTTGTCGCTGCGGATTGCTTCGGAAGAGAAGTCTCTTTTGATGCGTGC
TGCGGCAATACAGAATACGCATTTGACGGAGTTTGTCACCCGCACCGTTGTTTCTGCGGCTCAAAAGGTAATCGATCAGT
ACGAACTGATAGAGCTTACAGGGAGGGATCGCGTACATGTCCTGAAATTGCTGGAAGATCCTCCGCTACCTAATGCAAAA
CTCATGGCAGCAGCACGTGCTTTGCCGAAGCGATCATGA
ATGCCACAGATTCCGGTAGAAGGTAACGAGAGGTTGTCGCTGCGGATTGCTTCGGAAGAGAAGTCTCTTTTGATGCGTGC
TGCGGCAATACAGAATACGCATTTGACGGAGTTTGTCACCCGCACCGTTGTTTCTGCGGCTCAAAAGGTAATCGATCAGT
ACGAACTGATAGAGCTTACAGGGAGGGATCGCGTACATGTCCTGAAATTGCTGGAAGATCCTCCGCTACCTAATGCAAAA
CTCATGGCAGCAGCACGTGCTTTGCCGAAGCGATCATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|