Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1864057..1864202 Replicon chromosome
Accession NZ_CP089986
Organism Klebsiella pneumoniae strain LZKP00001

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1864093..1864195 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1864057..1864202 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LUA09_RS08995 (LUA09_08995) 1859187..1861247 + 2061 WP_004148850.1 oligopeptidase B -
LUA09_RS09000 (LUA09_09000) 1861251..1861910 - 660 WP_002911407.1 exodeoxyribonuclease X -
LUA09_RS09005 (LUA09_09005) 1861989..1862219 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LUA09_RS09010 (LUA09_09010) 1862332..1862706 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LUA09_RS09015 (LUA09_09015) 1862710..1863579 + 870 WP_004891049.1 copper homeostasis membrane protein CopD -
LUA09_RS09020 (LUA09_09020) 1863596..1863934 + 339 WP_002911404.1 YebY family protein -
- 1864057..1864202 - 146 - - Antitoxin
- 1864093..1864195 + 103 - - Toxin
LUA09_RS09025 (LUA09_09025) 1864570..1864713 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LUA09_RS09030 (LUA09_09030) 1864818..1865786 - 969 WP_014907334.1 VirK/YbjX family protein -
LUA09_RS09035 (LUA09_09035) 1865943..1866596 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
LUA09_RS09040 (LUA09_09040) 1866593..1866784 - 192 WP_002911395.1 YebW family protein -
LUA09_RS09045 (LUA09_09045) 1866882..1867121 - 240 WP_002911393.1 YebV family protein -
LUA09_RS09050 (LUA09_09050) 1867237..1868670 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T229848 NZ_CP089986:1864093-1864195 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT229848 NZ_CP089986:c1864202-1864057 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References