Detailed information of TA system TA229841

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 2888578..2889125
• Replicon: chromosome
• Accession: NZ_CP089985
• Organism: Pseudomonas sp. HN11

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: LVW35_RS13070
• Protein ID: WP_122728229.1
• Coordinates: 2888850..2889125 (+)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: LVW35_RS13065
• Protein ID: WP_122728231.1
• Coordinates: 2888578..2888850 (+)
• Length: 91 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LVW35_RS13055 (LVW35_13055)	2886578..2887819	-	1242	WP_233896043.1	exonuclease SbcCD subunit D C-terminal domain-containing protein	-
LVW35_RS13060 (LVW35_13060)	2887902..2888135	-	234	WP_233896044.1	DUF3077 domain-containing protein	-
LVW35_RS13065 (LVW35_13065)	2888578..2888850	+	273	WP_122728231.1	ribbon-helix-helix domain-containing protein	Antitoxin
LVW35_RS13070 (LVW35_13070)	2888850..2889125	+	276	WP_122728229.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
LVW35_RS13075 (LVW35_13075)	2889205..2890845	-	1641	WP_233896045.1	BatD family protein	-
LVW35_RS13080 (LVW35_13080)	2890842..2892578	-	1737	WP_233896047.1	tetratricopeptide repeat protein	-
LVW35_RS13085 (LVW35_13085)	2892575..2893663	-	1089	WP_233896050.1	VWA domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-90)

Antitoxin

• Ribbon-helix-helix protein, CopG (10-47)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10698.38 Da
• Isoelectric Point: 8.5042

>T229841 WP_122728229.1 NZ_CP089985:2888850-2889125 [Pseudomonas sp. HN11]
MELKWTAKALSDLARLYEFLALVNQPAAARTVQQLTAAPMTLLANPRIGERLEEFEPRDVRRIQIGHYEMRYEIVGSTVY
LLRLWHTREDR

Nucleotide

• Length: 276 bp

>T229841 NZ_CP124543:c4137515-4137138 [Halotia branconii CENA392]
ATGGTTGATCAGCCTTTGATTCAAGTTCAAGCTTCGCCAACGTTTAAACGAAATATACGCGCTCTTGCTAAAAAATATCG
CAGTATTCGGAATGACATACAACCTGTTATCGAACAACTTCAGCAGGGAGAGTTATCAGGAGATCAAATACCTGGTGTTG
GTTATGCAATCTTCAAGTTGAGAGTCCGAAATAGCGACGCTCAAAAAGGTAAAAGTGGCGGCTATCGTCTGATTTATTAC
GTCAAAACAGCAACTGGAATCATTCTACTGACTGTTTATACCAAATCTAAACAAGTTGATATTGCAGCAAAAGATATTCA
GAGCATCATTGCAGAATATGAGCAACAGACAATCAATGATGAAGAAAGGGATATATAA

Antitoxin

Protein

• Length: 91 a.a.
• Molecular weight: 10071.34 Da
• Isoelectric Point: 5.6994

>AT229841 WP_122728231.1 NZ_CP089985:2888578-2888850 [Pseudomonas sp. HN11]
MATPSKTRSVTAHVPEQLAQKVDLMAERLERSRNWIVKQALSAWIDQEEERSRLTREALADVDAGRVIDHQAVQAWADSL
SGDAPLPVPR

Nucleotide

• Length: 273 bp

>AT229841 NZ_CP124543:c4137750-4137508 [Halotia branconii CENA392]
ATGAAAGCACTTAAAGTTATGGCAACGATTAACGATCAGGGACAACTAACTTTAGATCATCCGCTTTTAACTGATAAAAA
TAGCCGAGTAGAAGTCATTGTGCTAATCCCTGAAGAAGAAGAAGTTCTCGATGATCAATCTCAAGTAGAAGTCTTAGCAG
ATTTCCGGCAAGCTTGGCACGAAGCCATGACTGGGCACACTATCCCGGTGGCTCAACTTTGGGAAGGTCTTGAAGATGGT
TGA