Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 2888578..2889125 Replicon chromosome
Accession NZ_CP089985
Organism Pseudomonas sp. HN11

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LVW35_RS13070 Protein ID WP_122728229.1
Coordinates 2888850..2889125 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LVW35_RS13065 Protein ID WP_122728231.1
Coordinates 2888578..2888850 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LVW35_RS13055 (LVW35_13055) 2886578..2887819 - 1242 WP_233896043.1 exonuclease SbcCD subunit D C-terminal domain-containing protein -
LVW35_RS13060 (LVW35_13060) 2887902..2888135 - 234 WP_233896044.1 DUF3077 domain-containing protein -
LVW35_RS13065 (LVW35_13065) 2888578..2888850 + 273 WP_122728231.1 ribbon-helix-helix domain-containing protein Antitoxin
LVW35_RS13070 (LVW35_13070) 2888850..2889125 + 276 WP_122728229.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LVW35_RS13075 (LVW35_13075) 2889205..2890845 - 1641 WP_233896045.1 BatD family protein -
LVW35_RS13080 (LVW35_13080) 2890842..2892578 - 1737 WP_233896047.1 tetratricopeptide repeat protein -
LVW35_RS13085 (LVW35_13085) 2892575..2893663 - 1089 WP_233896050.1 VWA domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-47)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10698.38 Da        Isoelectric Point: 8.5042

>T229841 WP_122728229.1 NZ_CP089985:2888850-2889125 [Pseudomonas sp. HN11]
MELKWTAKALSDLARLYEFLALVNQPAAARTVQQLTAAPMTLLANPRIGERLEEFEPRDVRRIQIGHYEMRYEIVGSTVY
LLRLWHTREDR

Download         Length: 276 bp

>T229841 NZ_CP124543:c4137515-4137138 [Halotia branconii CENA392]
ATGGTTGATCAGCCTTTGATTCAAGTTCAAGCTTCGCCAACGTTTAAACGAAATATACGCGCTCTTGCTAAAAAATATCG
CAGTATTCGGAATGACATACAACCTGTTATCGAACAACTTCAGCAGGGAGAGTTATCAGGAGATCAAATACCTGGTGTTG
GTTATGCAATCTTCAAGTTGAGAGTCCGAAATAGCGACGCTCAAAAAGGTAAAAGTGGCGGCTATCGTCTGATTTATTAC
GTCAAAACAGCAACTGGAATCATTCTACTGACTGTTTATACCAAATCTAAACAAGTTGATATTGCAGCAAAAGATATTCA
GAGCATCATTGCAGAATATGAGCAACAGACAATCAATGATGAAGAAAGGGATATATAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10071.34 Da        Isoelectric Point: 5.6994

>AT229841 WP_122728231.1 NZ_CP089985:2888578-2888850 [Pseudomonas sp. HN11]
MATPSKTRSVTAHVPEQLAQKVDLMAERLERSRNWIVKQALSAWIDQEEERSRLTREALADVDAGRVIDHQAVQAWADSL
SGDAPLPVPR

Download         Length: 273 bp

>AT229841 NZ_CP124543:c4137750-4137508 [Halotia branconii CENA392]
ATGAAAGCACTTAAAGTTATGGCAACGATTAACGATCAGGGACAACTAACTTTAGATCATCCGCTTTTAACTGATAAAAA
TAGCCGAGTAGAAGTCATTGTGCTAATCCCTGAAGAAGAAGAAGTTCTCGATGATCAATCTCAAGTAGAAGTCTTAGCAG
ATTTCCGGCAAGCTTGGCACGAAGCCATGACTGGGCACACTATCCCGGTGGCTCAACTTTGGGAAGGTCTTGAAGATGGT
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References