Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 665224..665816 Replicon chromosome
Accession NZ_CP089985
Organism Pseudomonas sp. HN11

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag LVW35_RS02915 Protein ID WP_233893634.1
Coordinates 665508..665816 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LVW35_RS02910 Protein ID WP_233893633.1
Coordinates 665224..665511 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LVW35_RS02885 (LVW35_02885) 660227..661603 - 1377 WP_233893628.1 PepSY domain-containing protein -
LVW35_RS02890 (LVW35_02890) 661647..663707 - 2061 WP_233893629.1 TonB-dependent copper receptor -
LVW35_RS02895 (LVW35_02895) 663801..664190 - 390 WP_233893630.1 DUF2946 domain-containing protein -
LVW35_RS02900 (LVW35_02900) 664202..664684 - 483 WP_233893631.1 copper chaperone PCu(A)C -
LVW35_RS02905 (LVW35_02905) 664731..665126 - 396 WP_233893632.1 DUF2946 domain-containing protein -
LVW35_RS02910 (LVW35_02910) 665224..665511 - 288 WP_233893633.1 putative addiction module antidote protein Antitoxin
LVW35_RS02915 (LVW35_02915) 665508..665816 - 309 WP_233893634.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LVW35_RS02920 (LVW35_02920) 666248..666967 - 720 WP_233893635.1 cobalt-precorrin-6A reductase -
LVW35_RS02925 (LVW35_02925) 666964..668169 - 1206 WP_233893636.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -
LVW35_RS02930 (LVW35_02930) 668208..669554 + 1347 WP_233893638.1 precorrin-3B synthase -
LVW35_RS02935 (LVW35_02935) 669547..670173 + 627 WP_233893640.1 precorrin-8X methylmutase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-95)

Antitoxin

Uncharacterized protein HI1420

(2-94)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11720.18 Da        Isoelectric Point: 9.5427

>T229837 WP_233893634.1 NZ_CP089985:c665816-665508 [Pseudomonas sp. HN11]
MIRFKRSDEFQEWLDSSRSRPARGRVLTRLDNATRGNFGDCAPVGNGVSEMRIHYGPGYRVYFTRVDEVVYLLLIGGDKS
TQKRDIQRAKEMADEFGIRSDS

Download         Length: 309 bp

>T229837 NZ_CP124543:1975427-1975690 [Halotia branconii CENA392]
ATGACTGTTTTTGAATATGACGAAAACAAAAGCCAATCTAATTTTGTTAAACATGGGATTGACTTTATTGAAGCTCAAAA
ATTATGGAACGATCCCAACCTGCTAGAAATTCCGGCCAGAACCCAAGATGAGCTAAGGTTTTTAGTTATTGCTAAGATAG
ATAACAAACATTGGTCAAGAGTTATCACCTACCGCGATCAAAATATTCGGATCATATCCGTCCACCGATCACGCACAGAA
GAGATTGCCTTATATGACAGCTAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10360.84 Da        Isoelectric Point: 4.8047

>AT229837 WP_233893633.1 NZ_CP089985:c665511-665224 [Pseudomonas sp. HN11]
MTQFKDFDIAEHLKTPEDMAEYLEASFEEDSGDGLLIRSALNNIARAQGMTQIARDAGLGRESLYKALSATGNPEFATIM
KVMKALGLKLHATAI

Download         Length: 288 bp

>AT229837 NZ_CP124543:1975680-1975910 [Halotia branconii CENA392]
ATGACAGCTAAGGAATTTGACCAAAAGTTTGACGATGGTGAAGACATAACCGAAATGCTTGACCTATCTAAAGCCAAGCG
TCCCCTGTCTGCTCAAAAAAAAGTCAGCATAGAGCTGCCCATCTGGATGATTGAATTAATTGATCAAGAAGCAAACCGTT
TAGGAGTAACGCCCCAGACAATTATCCAAACCTTTTTAGCTGAACATTTAGCCGTCAACAACCCCTCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References