Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 629657..630171 Replicon chromosome
Accession NZ_CP089980
Organism Fulvivirga sp. SW1-E11

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LVD15_RS02695 Protein ID WP_233778749.1
Coordinates 629657..629917 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LVD15_RS02700 Protein ID WP_233778750.1
Coordinates 629917..630171 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LVD15_RS02665 (LVD15_02665) 624930..625346 - 417 WP_233778743.1 hypothetical protein -
LVD15_RS02670 (LVD15_02670) 625524..626258 - 735 WP_233778744.1 copper homeostasis protein CutC -
LVD15_RS02675 (LVD15_02675) 626375..627838 - 1464 WP_233778745.1 TlpA disulfide reductase family protein -
LVD15_RS02680 (LVD15_02680) 627968..628285 + 318 WP_233778746.1 hypothetical protein -
LVD15_RS02685 (LVD15_02685) 628278..628943 + 666 WP_233778747.1 ATP-binding cassette domain-containing protein -
LVD15_RS02690 (LVD15_02690) 628951..629619 - 669 WP_233778748.1 hypothetical protein -
LVD15_RS02695 (LVD15_02695) 629657..629917 - 261 WP_233778749.1 Txe/YoeB family addiction module toxin Toxin
LVD15_RS02700 (LVD15_02700) 629917..630171 - 255 WP_233778750.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LVD15_RS02705 (LVD15_02705) 630362..630751 + 390 WP_233778751.1 group III truncated hemoglobin -
LVD15_RS02710 (LVD15_02710) 630748..631248 + 501 WP_233778752.1 GNAT family N-acetyltransferase -
LVD15_RS02715 (LVD15_02715) 631302..632339 + 1038 WP_233778753.1 potassium channel family protein -
LVD15_RS02720 (LVD15_02720) 632386..632952 + 567 WP_233778754.1 pseudouridine synthase -
LVD15_RS02725 (LVD15_02725) 633031..634197 - 1167 WP_233778755.1 porin -
LVD15_RS02730 (LVD15_02730) 634204..634932 - 729 WP_233778756.1 SdiA-regulated domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10326.86 Da        Isoelectric Point: 9.3098

>T229835 WP_233778749.1 NZ_CP089980:c629917-629657 [Fulvivirga sp. SW1-E11]
VNVIFSHNAWEDYTSWLKEDRKILKKINDLVKDIKRTPLEGIGKPEPLKYELSGYWSRRIDREHRLVYQVSGADLIIFSC
KYHYDK

Download         Length: 261 bp

>T229835 NZ_CP124534:c4695024-4694872 [Xanthomonas campestris]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTCTCGGCCGGCATGATGACTGGCTGTAACACCATGGCTGGTGC
CGGAAAGGACATGCAGGGTGCGGGTGACAAGGTCGAGAAGACCGCCGACAAATGCAGCGACGGTAAGTGCTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9548.91 Da        Isoelectric Point: 7.0107

>AT229835 WP_233778750.1 NZ_CP089980:c630171-629917 [Fulvivirga sp. SW1-E11]
MIAANYTEFRTNLKKYLDDVEQNQETLIVKRGTGNGTVMISLDEYNSLMETVHLLSSKKNADRLFESIQQIKDGKVVKRG
LIEG

Download         Length: 255 bp

>AT229835 NZ_CP124534:c4694795-4694661 [Xanthomonas campestris]
ATGAAGCGTGCAATTGCATTGTTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCCGCGCGCAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References