Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 752272..752921 Replicon chromosome
Accession NZ_CP089977
Organism Moraxella nasicaprae strain ZY201224

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LU297_RS03580 Protein ID WP_263077053.1
Coordinates 752532..752921 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LU297_RS03575 Protein ID WP_263077052.1
Coordinates 752272..752505 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LU297_RS03545 (LU297_03560) 747382..747885 + 504 WP_263077045.1 GNAT family N-acetyltransferase -
LU297_RS03550 (LU297_03565) 747900..748115 + 216 WP_263077046.1 hypothetical protein -
LU297_RS03555 (LU297_03570) 748112..748510 + 399 WP_263077047.1 type II toxin-antitoxin system VapC family toxin -
LU297_RS03560 (LU297_03575) 748541..750010 + 1470 WP_263077049.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
LU297_RS03570 (LU297_03585) 750485..751684 + 1200 WP_263077051.1 tyrosine-type recombinase/integrase -
LU297_RS03575 (LU297_03590) 752272..752505 + 234 WP_263077052.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
LU297_RS03580 (LU297_03595) 752532..752921 + 390 WP_263077053.1 PIN domain-containing protein Toxin
LU297_RS03585 (LU297_03600) 753280..753528 + 249 WP_263077054.1 AlpA family phage regulatory protein -
LU297_RS03590 (LU297_03605) 753515..753760 + 246 WP_263077055.1 hypothetical protein -
LU297_RS03595 (LU297_03610) 753817..754293 + 477 WP_263077056.1 hypothetical protein -
LU297_RS03600 (LU297_03615) 754295..754501 + 207 WP_263077057.1 hypothetical protein -
LU297_RS03605 (LU297_03620) 754498..754683 + 186 WP_263077058.1 hypothetical protein -
LU297_RS03610 (LU297_03625) 754680..756971 + 2292 WP_263077059.1 DUF927 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-120)

Antitoxin

SpoVT-AbrB domain

(7-55)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14609.81 Da        Isoelectric Point: 7.2882

>T229831 WP_263077053.1 NZ_CP089977:752532-752921 [Moraxella nasicaprae]
MLDTNIVIHIIKQKPAKLLGKFNQYAGRICISAITASELWAGVYHSQRVYENGKILADFLSRIDVLPYKPDCCQYYGENY
AQLAKDGRLISENDLHIASHAKSLGLILVTNNTKEFARVQGLELQDWLE

Download         Length: 390 bp

>T229831 NZ_CP124533:c4691719-4691585 [Xanthomonas campestris]
ATGAAGCGTGCAATTGCATTGTTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCCGCGCGCAAGTGA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8787.00 Da        Isoelectric Point: 4.9611

>AT229831 WP_263077052.1 NZ_CP089977:752272-752505 [Moraxella nasicaprae]
MPITTVFMNNRTQAVRIPSGLKFNDDIKQVIIRKVGKELIISPQDGVWDSFFLSDERVSDDFDRPTPAMPSQRASFD

Download         Length: 234 bp

>AT229831 NZ_CP124533:c4691948-4691796 [Xanthomonas campestris]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTCTCGGCCGGCATGATGACTGGCTGTAACACCATGGCTGGTGC
CGGAAAGGACATGCAGGGTGCGGGTGACAAGGTCGAGAAGACCGCCGACAAATGCAGCGACGGTAAGTGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References