Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /-
Location 1828073..1828853 Replicon chromosome
Accession NC_011060
Organism Pelodictyon phaeoclathratiforme BU-1

Toxin (Protein)


Gene name tacT Uniprot ID B4SB07
Locus tag PPHA_RS08505 Protein ID WP_012508440.1
Coordinates 1828350..1828853 (-) Length 168 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID B4SB06
Locus tag PPHA_RS08500 Protein ID WP_012508439.1
Coordinates 1828073..1828300 (-) Length 76 a.a.

Genomic Context

PPHA_RS08470PPHA_RS08475PPHA_RS08480PPHA_RS08485PPHA_RS08535PPHA_RS08540PPHA_RS08490PPHA_RS08495PPHA_RS08500PPHA_RS08505PPHA_RS08510PPHA_RS15115PPHA_RS08520PPHA_RS08525PPHA_RS08530PPHA_RS08545
Location: 1823395..1823631 (237 bp)
Type: Others
Protein ID: Protein_1659
Location: 1823841..1824407 (567 bp)
Type: Others
Protein ID: WP_041526793.1
Location: 1824416..1826869 (2454 bp)
Type: Others
Protein ID: WP_012508435.1
Location: 1827057..1827290 (234 bp)
Type: Others
Protein ID: WP_041526794.1
Location: 1832032..1832358 (327 bp)
Type: Others
Protein ID: WP_012508445.1
Location: 1832351..1832677 (327 bp)
Type: Others
Protein ID: WP_012508446.1
Location: 1827457..1827669 (213 bp)
Type: Others
Protein ID: WP_041526492.1
Location: 1827650..1827931 (282 bp)
Type: Others
Protein ID: WP_012508438.1
Location: 1828073..1828300 (228 bp)
Type: Antitoxin
Protein ID: WP_012508439.1
Location: 1828350..1828853 (504 bp)
Type: Toxin
Protein ID: WP_012508440.1
Location: 1828860..1829138 (279 bp)
Type: Others
Protein ID: WP_012508441.1
Location: 1829228..1830236 (1009 bp)
Type: Others
Protein ID: Protein_1668
Location: 1830494..1830883 (390 bp)
Type: Others
Protein ID: WP_012508442.1
Location: 1830880..1831110 (231 bp)
Type: Others
Protein ID: WP_012508443.1
Location: 1831362..1831613 (252 bp)
Type: Others
Protein ID: WP_012508444.1
Location: 1832737..1832918 (182 bp)
Type: Others
Protein ID: Protein_1674
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PPHA_RS084701823395..1823631+237Protein_1659hypothetical protein-
PPHA_RS084751823841..1824407+567WP_041526793.1hypothetical protein-
PPHA_RS084801824416..1826869+2454WP_012508435.1tetratricopeptide repeat protein-
PPHA_RS084851827057..1827290+234WP_041526794.1hypothetical protein-
PPHA_RS084901827457..1827669-213WP_041526492.1hypothetical protein-
PPHA_RS084951827650..1827931-282WP_012508438.1BrnT family toxin-
PPHA_RS085001828073..1828300-228WP_012508439.1CopG family transcriptional regulatorAntitoxin
PPHA_RS085051828350..1828853-504WP_012508440.1GNAT family N-acetyltransferaseToxin
PPHA_RS085101828860..1829138-279WP_012508441.1DUF1778 domain-containing protein-
PPHA_RS151151829228..1830236-1009Protein_1668ABC transporter permease-
PPHA_RS085201830494..1830883-390WP_012508442.1type II toxin-antitoxin system VapC family toxin-
PPHA_RS085251830880..1831110-231WP_012508443.1hypothetical protein-
PPHA_RS085301831362..1831613-252WP_012508444.1UPF0175 family protein-
PPHA_RS085351832032..1832358+327WP_012508445.1type II toxin-antitoxin system RelE/ParE family toxin-
PPHA_RS085401832351..1832677+327WP_012508446.1helix-turn-helix domain-containing protein-
PPHA_RS085451832737..1832918-182Protein_1674ABC transporter ATP-binding protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(87-147)

Antitoxin

CopG antitoxin

(1-68)


Sequences

Toxin        


Download         Length: 168 a.a.        Molecular weight: 18861.71 Da        Isoelectric Point: 9.3881

>T22983 WP_012508440.1 NC_011060:c1828853-1828350 [Pelodictyon phaeoclathratiforme BU-1]
MSTRFSIEKPRSDHDRADFDCGSKELNRFLVRYALVNQQACSSQTYVGLADLSIVGFYTLAVGQVNYEDSPQRLIRGVAR
HPVPIMLLARLAVSNKWQKRGIGAGLLKDAMRRTMQAADIAGIRAFAVHAKDEAAQEFYAHFDFIPSPTDPYHMFLLLKD
IRRMIGE

Download         Length: 504 bp

>T22983 NC_011060:c1828853-1828350 [Pelodictyon phaeoclathratiforme BU-1]
ATGTCAACGCGCTTCTCCATTGAAAAGCCACGCAGTGATCATGATAGAGCAGATTTTGATTGCGGCAGCAAGGAACTAAA
CCGGTTCCTTGTTCGCTATGCTCTGGTCAATCAACAGGCTTGTTCATCGCAAACCTATGTCGGGCTGGCAGACCTTTCGA
TTGTCGGCTTCTATACACTTGCCGTTGGTCAGGTAAATTATGAAGATTCGCCACAACGCCTCATCAGGGGAGTCGCGCGA
CATCCGGTTCCAATCATGTTGCTGGCACGTCTGGCTGTGAGCAACAAATGGCAGAAGCGCGGGATTGGCGCTGGCCTTTT
GAAAGACGCAATGCGACGAACTATGCAAGCCGCTGATATTGCAGGTATCCGAGCCTTCGCTGTCCACGCCAAAGATGAGG
CTGCGCAGGAATTTTATGCGCATTTTGATTTTATCCCCTCACCGACCGACCCATATCATATGTTTCTGTTACTCAAAGAT
ATTCGTCGGATGATTGGTGAGTAG

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8723.99 Da        Isoelectric Point: 8.0185

>AT22983 WP_012508439.1 NC_011060:c1828300-1828073 [Pelodictyon phaeoclathratiforme BU-1]
MKTEEFDKQFDDGADITNFLDLSKAKRIKQQHKRVDVDFPVRMIDSLDKEATCLGVSRQSVIKVWLGERLQQQKA

Download         Length: 228 bp

>AT22983 NC_011060:c1828300-1828073 [Pelodictyon phaeoclathratiforme BU-1]
ATGAAAACAGAGGAATTTGACAAGCAATTTGATGATGGTGCAGATATCACCAATTTCCTTGACCTGAGCAAGGCGAAAAG
GATAAAACAACAGCACAAAAGGGTGGATGTTGATTTCCCTGTCAGGATGATTGACTCACTCGATAAAGAGGCAACCTGTC
TTGGCGTATCGCGTCAGTCTGTGATTAAAGTTTGGCTCGGAGAACGTCTTCAACAACAGAAGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBB4SB07

Antitoxin

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Source
ID
Structure
AlphaFold DBB4SB06

References