Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-VagC
Location 17939..18561 Replicon chromosome
Accession NZ_CP089976
Organism Moraxella nasovis strain ZY201115

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LU293_RS00160 Protein ID WP_242747777.1
Coordinates 17939..18331 (-) Length 131 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LU293_RS00165 Protein ID WP_242747779.1
Coordinates 18328..18561 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LU293_RS00100 (LU293_00100) 13031..13255 - 225 WP_242747752.1 hypothetical protein -
LU293_RS00105 (LU293_00105) 13312..13662 - 351 WP_242747755.1 hypothetical protein -
LU293_RS00110 (LU293_00110) 13628..14266 - 639 WP_242747757.1 hypothetical protein -
LU293_RS00115 (LU293_00115) 14526..14924 - 399 WP_256462112.1 type II toxin-antitoxin system VapC family toxin -
LU293_RS00120 (LU293_00120) 14918..15136 - 219 WP_242747761.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
LU293_RS00125 (LU293_00125) 15530..15685 - 156 WP_242747763.1 hypothetical protein -
LU293_RS00130 (LU293_00130) 15735..16004 - 270 WP_242747765.1 hypothetical protein -
LU293_RS00135 (LU293_00135) 16198..16434 - 237 WP_242747767.1 hypothetical protein -
LU293_RS00140 (LU293_00140) 16676..16972 - 297 WP_242747769.1 helix-turn-helix transcriptional regulator -
LU293_RS00145 (LU293_00145) 17020..17283 - 264 WP_242747771.1 XRE family transcriptional regulator -
LU293_RS00150 (LU293_00150) 17289..17411 - 123 WP_256462131.1 type II toxin-antitoxin system RelE/ParE family toxin -
LU293_RS00155 (LU293_00155) 17427..17606 - 180 WP_242747775.1 hypothetical protein -
LU293_RS00160 (LU293_00160) 17939..18331 - 393 WP_242747777.1 type II toxin-antitoxin system VapC family toxin Toxin
LU293_RS00165 (LU293_00165) 18328..18561 - 234 WP_242747779.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
LU293_RS00170 (LU293_00170) 18750..19145 - 396 WP_242747781.1 hypothetical protein -
LU293_RS00175 (LU293_00175) 19489..19911 - 423 WP_242747783.1 ImmA/IrrE family metallo-endopeptidase -
LU293_RS00180 (LU293_00180) 20042..20296 - 255 WP_242747785.1 hypothetical protein -
LU293_RS00185 (LU293_00185) 20334..20705 - 372 WP_242747787.1 hypothetical protein -
LU293_RS00190 (LU293_00190) 21839..22180 - 342 WP_242747789.1 hypothetical protein -
LU293_RS00195 (LU293_00195) 22417..23064 + 648 WP_242747791.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-122)

Antitoxin

SpoVT-AbrB domain

(9-42)


Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 14962.45 Da        Isoelectric Point: 9.8541

>T229828 WP_242747777.1 NZ_CP089976:c18331-17939 [Moraxella nasovis]
MKYLLDTNIIIALQKQNPVLIARLKQRKVSDFALSDIVLFELYYGAYHSQKQRENLAKIDKLPFVRLPFDDKDALCAGKV
RADLQRQGQVIGAYDMLIAGQALSKNLTLITHNVKEFSRVDGLKWQNWLE

Download         Length: 393 bp

>T229828 NZ_CP124531:c4699142-4699008 [Xanthomonas campestris]
ATGAAGCGTGCAATTGCATTGTTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCCGCGCGCAAGTGA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8875.06 Da        Isoelectric Point: 4.5142

>AT229828 WP_242747779.1 NZ_CP089976:c18561-18328 [Moraxella nasovis]
MITARLFYSGNSQAIRLPKEFRFDGDKVQLKKHGNQLIITPIIDDWGWLDDVSSFDDDMEQAVAMLKDDPISKRDFA

Download         Length: 234 bp

>AT229828 NZ_CP124531:c4699371-4699219 [Xanthomonas campestris]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTCTCGGCCGGCATGATGACTGGCTGTAACACCATGGCTGGTGC
CGGAAAGGACATGCAGGGTGCGGGTGACAAGGTCGAGAAGACCGCCGACAAATGCAGCGACGGTAAGTGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References