Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-CC2985
Location 279363..279909 Replicon plasmid pORIO1
Accession NZ_CP089967
Organism Cereibacter azotoformans strain ORIO

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag ORIO_RS20845 Protein ID WP_011910870.1
Coordinates 279363..279656 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag ORIO_RS20850 Protein ID WP_011910869.1
Coordinates 279643..279909 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ORIO_RS20820 (ORIO_20820) 274581..274724 - 144 WP_181969655.1 hypothetical protein -
ORIO_RS20825 (ORIO_20825) 274939..276141 + 1203 WP_238823629.1 Fic family protein -
ORIO_RS20830 (ORIO_20830) 276236..277459 - 1224 WP_238823630.1 AAA family ATPase -
ORIO_RS20835 (ORIO_20835) 278015..278485 + 471 WP_238823631.1 hypothetical protein -
ORIO_RS20840 (ORIO_20840) 279030..279212 - 183 WP_044249733.1 hypothetical protein -
ORIO_RS20845 (ORIO_20845) 279363..279656 - 294 WP_011910870.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ORIO_RS20850 (ORIO_20850) 279643..279909 - 267 WP_011910869.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
ORIO_RS20855 (ORIO_20855) 280585..281958 + 1374 WP_233864266.1 Fic family protein -
ORIO_RS20860 (ORIO_20860) 282428..283759 - 1332 WP_011910866.1 HipA domain-containing protein -
ORIO_RS20865 (ORIO_20865) 283876..284070 - 195 Protein_259 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - glf / glf 1..309984 309984


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

Antitoxin ParD

(2-80)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11036.64 Da        Isoelectric Point: 7.4636

>T229820 WP_011910870.1 NZ_CP089967:c279656-279363 [Cereibacter azotoformans]
VTKIDFTRDAERDLIDIFLYGIEHFGPVQAERYTKTLNAKIDMAAEHPDFGADYGFVIKGVRRYEAVSHAIYYRSTGVGI
LVLRVLHGRMDPARHLA

Download         Length: 294 bp

>T229820 NZ_CP124526:c960550-960263 [Psychrobacter sp. WB2]
ATGACTTATAATCTTGAGTTTCATCCCTTAGCATTAAAAGAATGGAAAAAGTTAGCGCCCAGTATTCAGCAGCAGTTTAA
GAAAAAGTTACAGCAGCGCTTAGCAAGCCCTCGTGTTCCTGCGTCGAAACTTTCAGGACATACAGACGCCTATAAAATCA
AACTACGCACCATAGGCTATCGTCTGGTTTATACCGTCAAAGATGACGTGGTGGTGGTTTACGTGCTAGCCGTAGGCAAA
AGAGAAAACAATAAGGTATATGAAAGCCTTGTGTCGCGCCAACCATAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10073.22 Da        Isoelectric Point: 4.7064

>AT229820 WP_011910869.1 NZ_CP089967:c279909-279643 [Cereibacter azotoformans]
MSRLTISMPDQMNEWVEAQIAAGRYGNVSEYFRDLVRRDQERREAAVAELRTMLERADASGVSDRSFPDILEAARREARQ
KGLLGDEN

Download         Length: 267 bp

>AT229820 NZ_CP124526:c960791-960540 [Psychrobacter sp. WB2]
ATGCAACCAATATTTGCGACACAGACAGCCAGTATCTCAGAGCTGAAAAACAACCCTTCGGCACTGATTAAACAATCAGA
CGGTGAGTCTATTGCTATTTTAAACCACAATAAACCTGTCGCTTACTTAGTTTCCACAGACATGTATGAGCGCATGATGG
AAGCGATGGACGATATGGCATTAAGCCAAACGGTTAGCGCCCGAATGAATGACGGGCAAATACCTATAAAGGTCACATTG
GATGACTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References