Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 1822804..1823369 Replicon chromosome
Accession NC_011060
Organism Pelodictyon phaeoclathratiforme BU-1

Toxin (Protein)


Gene name vapC Uniprot ID B4SAZ9
Locus tag PPHA_RS08465 Protein ID WP_012508432.1
Coordinates 1823025..1823369 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID B4SAZ8
Locus tag PPHA_RS08460 Protein ID WP_012508431.1
Coordinates 1822804..1823028 (+) Length 75 a.a.

Genomic Context

PPHA_RS08430PPHA_RS08435PPHA_RS08455PPHA_RS08460PPHA_RS08465PPHA_RS08470PPHA_RS08475PPHA_RS08480PPHA_RS08485PPHA_RS08440PPHA_RS08445PPHA_RS08490PPHA_RS08495PPHA_RS08500
Location: 1819046..1820107 (1062 bp)
Type: Others
Protein ID: WP_012508426.1
Location: 1820141..1821337 (1197 bp)
Type: Others
Protein ID: WP_012508427.1
Location: 1822165..1822671 (507 bp)
Type: Others
Protein ID: WP_012508430.1
Location: 1822804..1823028 (225 bp)
Type: Antitoxin
Protein ID: WP_012508431.1
Location: 1823025..1823369 (345 bp)
Type: Toxin
Protein ID: WP_012508432.1
Location: 1823395..1823631 (237 bp)
Type: Others
Protein ID: Protein_1659
Location: 1823841..1824407 (567 bp)
Type: Others
Protein ID: WP_041526793.1
Location: 1824416..1826869 (2454 bp)
Type: Others
Protein ID: WP_012508435.1
Location: 1827057..1827290 (234 bp)
Type: Others
Protein ID: WP_041526794.1
Location: 1821344..1821637 (294 bp)
Type: Others
Protein ID: WP_012508428.1
Location: 1821634..1821840 (207 bp)
Type: Others
Protein ID: WP_012508429.1
Location: 1827457..1827669 (213 bp)
Type: Others
Protein ID: WP_041526492.1
Location: 1827650..1827931 (282 bp)
Type: Others
Protein ID: WP_012508438.1
Location: 1828073..1828300 (228 bp)
Type: Others
Protein ID: WP_012508439.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PPHA_RS084301819046..1820107+1062WP_012508426.1glycosyltransferase-
PPHA_RS084351820141..1821337+1197WP_012508427.1glycosyltransferase family 2 protein-
PPHA_RS084401821344..1821637-294WP_012508428.1type II toxin-antitoxin system RelE/ParE family toxin-
PPHA_RS084451821634..1821840-207WP_012508429.1addiction module protein-
PPHA_RS084551822165..1822671+507WP_012508430.1hypothetical protein-
PPHA_RS084601822804..1823028+225WP_012508431.1DUF433 domain-containing proteinAntitoxin
PPHA_RS084651823025..1823369+345WP_012508432.1DUF5615 family PIN-like proteinToxin
PPHA_RS084701823395..1823631+237Protein_1659hypothetical protein-
PPHA_RS084751823841..1824407+567WP_041526793.1hypothetical protein-
PPHA_RS084801824416..1826869+2454WP_012508435.1tetratricopeptide repeat protein-
PPHA_RS084851827057..1827290+234WP_041526794.1hypothetical protein-
PPHA_RS084901827457..1827669-213WP_041526492.1hypothetical protein-
PPHA_RS084951827650..1827931-282WP_012508438.1BrnT family toxin-
PPHA_RS085001828073..1828300-228WP_012508439.1CopG family transcriptional regulator-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(1-79)

Antitoxin

Protein of unknown function DUF433

(8-63)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 12721.59 Da        Isoelectric Point: 5.1281

>T22981 WP_012508432.1 NC_011060:1823025-1823369 [Pelodictyon phaeoclathratiforme BU-1]
MIIWIDAQLSPSIAAWINRSYPNIQAQSLRSLDLQRADDLAIFDAAKHTEAVIKSKDSDFLKLVDQFGTPPQIIWITCGN
TSNNRMRAVLEKSLEKAVELIRSGEPIVEIGDKA

Download         Length: 345 bp

>T22981 NC_011060:1823025-1823369 [Pelodictyon phaeoclathratiforme BU-1]
ATGATCATCTGGATTGATGCACAACTATCCCCCTCTATTGCTGCATGGATCAACCGCAGCTATCCGAATATTCAGGCACA
ATCACTGAGGTCTCTCGATCTTCAGCGAGCGGATGATCTTGCCATATTTGATGCCGCAAAACATACCGAAGCAGTGATCA
AGAGTAAAGATTCGGATTTCCTGAAACTTGTCGATCAGTTCGGCACGCCGCCTCAAATCATCTGGATCACTTGTGGTAAC
ACCTCGAACAACAGAATGAGAGCTGTTCTTGAAAAATCTCTTGAAAAGGCTGTGGAATTGATACGTTCAGGCGAGCCGAT
CGTGGAAATCGGTGACAAAGCCTGA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8282.58 Da        Isoelectric Point: 4.7376

>AT22981 WP_012508431.1 NC_011060:1822804-1823028 [Pelodictyon phaeoclathratiforme BU-1]
MTDWQKRITINPEQCGGRPCIRGLRIRVIDILDLLAAGLSSEEILDELPDLEKDDIQAALKYASRKLDHPVIAA

Download         Length: 225 bp

>AT22981 NC_011060:1822804-1823028 [Pelodictyon phaeoclathratiforme BU-1]
ATGACTGACTGGCAAAAACGGATCACGATTAACCCCGAACAATGTGGTGGAAGACCATGTATTCGGGGATTGCGTATAAG
GGTAATTGATATCCTTGACCTGCTGGCGGCTGGTCTCAGCTCTGAAGAAATTCTGGATGAACTACCCGATCTCGAAAAAG
ATGATATTCAGGCTGCGCTGAAATATGCAAGCCGCAAACTCGATCATCCTGTCATTGCGGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBB4SAZ9

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBB4SAZ8

References