Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1844659..1844804 Replicon chromosome
Accession NZ_CP089959
Organism Klebsiella pneumoniae strain KP403

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1844695..1844797 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1844659..1844804 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LVQ74_RS08955 (LVQ74_08945) 1839789..1841849 + 2061 WP_004151449.1 oligopeptidase B -
LVQ74_RS08960 (LVQ74_08950) 1841853..1842512 - 660 WP_002911407.1 exodeoxyribonuclease X -
LVQ74_RS08965 (LVQ74_08955) 1842591..1842821 - 231 WP_048254886.1 DNA polymerase III subunit theta -
LVQ74_RS08970 (LVQ74_08960) 1842934..1843308 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LVQ74_RS08975 (LVQ74_08965) 1843312..1844181 + 870 WP_004891049.1 copper homeostasis membrane protein CopD -
LVQ74_RS08980 (LVQ74_08970) 1844198..1844536 + 339 WP_016529031.1 YebY family protein -
- 1844659..1844804 - 146 - - Antitoxin
- 1844695..1844797 + 103 - - Toxin
LVQ74_RS08985 (LVQ74_08975) 1845172..1845315 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LVQ74_RS08990 (LVQ74_08980) 1845420..1846388 - 969 WP_004151446.1 VirK/YbjX family protein -
LVQ74_RS08995 (LVQ74_08985) 1846545..1847198 + 654 WP_020802220.1 protein-serine/threonine phosphatase -
LVQ74_RS09000 (LVQ74_08990) 1847195..1847386 - 192 WP_002911395.1 YebW family protein -
LVQ74_RS09005 (LVQ74_08995) 1847484..1847723 - 240 WP_002911393.1 YebV family protein -
LVQ74_RS09010 (LVQ74_09000) 1847839..1849272 - 1434 WP_071081310.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T229800 NZ_CP089959:1844695-1844797 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT229800 NZ_CP089959:c1844804-1844659 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References