Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4697400..4697763 Replicon chromosome
Accession NZ_CP089952
Organism Xanthomonas campestris pv. campestris strain SB80

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag LR085_RS20820 Protein ID WP_011270059.1
Coordinates 4697400..4697534 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag LR085_RS20825 Protein ID WP_011038999.1
Coordinates 4697611..4697763 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LR085_RS20800 (LR085_20800) 4692666..4694318 - 1653 WP_172973909.1 M28 family metallopeptidase -
LR085_RS20805 (LR085_20805) 4694482..4695426 - 945 WP_172973853.1 MBL fold metallo-hydrolase -
LR085_RS20810 (LR085_20810) 4695510..4696799 - 1290 WP_172973854.1 tryptophan--tRNA ligase -
LR085_RS20815 (LR085_20815) 4696959..4697168 - 210 WP_011038998.1 CsbD family protein -
LR085_RS20820 (LR085_20820) 4697400..4697534 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
LR085_RS20825 (LR085_20825) 4697611..4697763 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
LR085_RS20830 (LR085_20830) 4697874..4698797 - 924 Protein_4048 arginase -
LR085_RS20835 (LR085_20835) 4699111..4699572 + 462 WP_011039001.1 roadblock/LC7 domain-containing protein -
LR085_RS20840 (LR085_20840) 4699655..4700014 + 360 WP_011039002.1 hypothetical protein -
LR085_RS20845 (LR085_20845) 4700117..4701034 + 918 WP_011039003.1 hypothetical protein -
LR085_RS20850 (LR085_20850) 4701031..4701573 + 543 WP_011039004.1 GTPase -
LR085_RS20855 (LR085_20855) 4701908..4702591 + 684 WP_011039005.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T229796 WP_011270059.1 NZ_CP089952:c4697534-4697400 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T229796 NZ_CP124517:4130379-4130663 [Escherichia coli]
ATGCAATTTACGGTATACCGCAGTCGCGGCAGGAACGCCGCGTTTCCCTTTGTTATTGATGTTACCAGCGACATTATTGG
TGAGATTAATCGCCGTATCGTTATTCCATTAACACCTATTGAACGATTTAGCCGTATTCGCCCACCAGAACGGCTTAACC
CAATCCTTTTACTGATAGACGGCAAAGAATATGTGCTCATGACGCATGAGACTGCAACTGTTCCAGTTAACGCGCTGGGA
ACGAAATTTTGCGATGCCAGCGCGCACCGAACGTTGATTAAATGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT229796 WP_011038999.1 NZ_CP089952:c4697763-4697611 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT229796 NZ_CP124517:4130143-4130376 [Escherichia coli]
ATGACTGCAAAACGTACCACACAAAGTGTGACCGTCACCGTCGACCGTGAGTTAGTCAATCGCGCTCGTGATGCAGGCTT
AAATATGAGCGCCACCCTTACGGTTGCGCTCAATGCTGAACTTAAAAAACATGCAGCAACACGTTGGCGTGAAGAGAACG
CAGAAGCTATCGCTGCGTTAAATCAATTGGCTGATGAAACCGGATGTTTCTCTGATGAGTACCGGAGCTTCTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References