Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 16915..17450 Replicon plasmid pETR001-a
Accession NZ_CP089943
Organism Erwinia tracheiphila strain MDCuke

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LU604_RS25930 Protein ID WP_233480948.1
Coordinates 17163..17450 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LU604_RS25925 Protein ID WP_233480947.1
Coordinates 16915..17166 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LU604_RS25910 (LU604_25910) 12924..14120 + 1197 WP_233480944.1 conjugal transfer protein TraW -
LU604_RS25915 (LU604_25915) 14117..14629 + 513 WP_233480945.1 conjugal transfer protein TraX -
LU604_RS25920 (LU604_25920) 14654..16825 + 2172 WP_233480946.1 DotA/TraY family protein -
LU604_RS25925 (LU604_25925) 16915..17166 + 252 WP_233480947.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LU604_RS25930 (LU604_25930) 17163..17450 + 288 WP_233480948.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LU604_RS25935 (LU604_25935) 17467..18147 + 681 WP_233480949.1 plasmid IncI1-type surface exclusion protein ExcA -
LU604_RS25940 (LU604_25940) 18233..19504 + 1272 WP_233480950.1 conjugal transfer protein TrbA -
LU604_RS25945 (LU604_25945) 19509..20573 + 1065 WP_233480951.1 thioredoxin fold domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..71258 71258


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11089.10 Da        Isoelectric Point: 10.7439

>T229784 WP_233480948.1 NZ_CP089943:17163-17450 [Erwinia tracheiphila]
MTYRVKFRTDALKEWNNLDKAIQQQFVRKLKKCAENPHIPSAKLRGMPDCYKIKLQASGFRLVYQVINDELIIAVVAVGK
REHSKVYNLASKRLR

Download         Length: 288 bp

>T229784 NZ_CP124517:c2230463-2230056 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATTCCCTGGCCGCTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGCATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCGCCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGACAGCGGAAAACGGCA
ACATTTATGGCTGGCAGCTGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATATTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9203.44 Da        Isoelectric Point: 4.5144

>AT229784 WP_233480947.1 NZ_CP089943:16915-17166 [Erwinia tracheiphila]
MPNLIHSDTTASISELKKNPMATVNAGAGSPVAILNHNQPAFYCVPAELYEQMLEYIDEEELAKLVTKRSKQALHDVDLD
SYL

Download         Length: 252 bp

>AT229784 NZ_CP124517:c2230710-2230444 [Escherichia coli]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCACCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCAGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References