Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 4893575..4894242 Replicon chromosome
Accession NC_011004
Organism Rhodopseudomonas palustris TIE-1

Toxin (Protein)


Gene name vapC Uniprot ID B3QJT1
Locus tag RPAL_RS22450 Protein ID WP_012497352.1
Coordinates 4893832..4894242 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID B3QJT0
Locus tag RPAL_RS22445 Protein ID WP_012497351.1
Coordinates 4893575..4893832 (+) Length 86 a.a.

Genomic Context

RPAL_RS22435RPAL_RS22445RPAL_RS22450RPAL_RS22455RPAL_RS22430RPAL_RS22440RPAL_RS22460RPAL_RS22465
Location: 4890340..4891026 (687 bp)
Type: Others
Protein ID: WP_012497350.1
Location: 4893575..4893832 (258 bp)
Type: Antitoxin
Protein ID: WP_012497351.1
Location: 4893832..4894242 (411 bp)
Type: Toxin
Protein ID: WP_012497352.1
Location: 4894362..4895021 (660 bp)
Type: Others
Protein ID: WP_012497353.1
Location: 4889767..4890192 (426 bp)
Type: Others
Protein ID: WP_210160543.1
Location: 4891215..4892814 (1600 bp)
Type: Others
Protein ID: Protein_4510
Location: 4895398..4896807 (1410 bp)
Type: Others
Protein ID: WP_012497354.1
Location: 4897068..4898264 (1197 bp)
Type: Others
Protein ID: WP_011159551.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
RPAL_RS224304889767..4890192-426WP_210160543.1hotdog fold thioesterase-
RPAL_RS224354890340..4891026+687WP_012497350.1YafY family transcriptional regulator-
RPAL_RS224404891215..4892814-1600Protein_4510ABC-F family ATP-binding cassette domain-containing protein-
RPAL_RS224454893575..4893832+258WP_012497351.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
RPAL_RS224504893832..4894242+411WP_012497352.1type II toxin-antitoxin system VapC family toxinToxin
RPAL_RS224554894362..4895021+660WP_012497353.1hypothetical protein-
RPAL_RS224604895398..4896807-1410WP_012497354.1adenosylhomocysteinase-
RPAL_RS224654897068..4898264-1197WP_011159551.1methionine adenosyltransferase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-118)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-53)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 14968.23 Da        Isoelectric Point: 10.1786

>T22967 WP_012497352.1 NC_011004:4893832-4894242 [Rhodopseudomonas palustris TIE-1]
MFLIDTVTLSALRKRQRNPNVVAWFERQRTADLFLSAISIGEIERGIARQRATDPEFARALAAWLDRVLTVYGERIVPFD
LRAARRWGALSAALGNDSADLMIAATALEHGLTVVTRNVSDFALTGVALIDPFGKA

Download         Length: 411 bp

>T22967 NC_011004:4893832-4894242 [Rhodopseudomonas palustris TIE-1]
ATGTTTCTGATCGACACCGTCACGCTGTCGGCCTTGCGCAAGCGACAGCGGAATCCGAATGTCGTCGCTTGGTTCGAACG
GCAGCGGACGGCCGACCTCTTCCTCAGCGCCATCAGCATCGGCGAGATCGAGCGCGGCATTGCGCGGCAACGCGCGACCG
ATCCGGAGTTTGCGCGCGCACTCGCCGCCTGGCTCGACCGGGTCCTGACCGTCTATGGTGAGCGCATCGTCCCATTCGAT
CTCCGAGCGGCACGTCGCTGGGGCGCCCTCAGCGCAGCGCTCGGCAACGACAGCGCCGACCTGATGATCGCCGCCACCGC
GCTGGAGCACGGACTGACCGTGGTGACGCGGAACGTGTCAGATTTCGCACTGACCGGCGTGGCGTTGATTGATCCGTTCG
GAAAGGCGTAG

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9627.86 Da        Isoelectric Point: 5.8432

>AT22967 WP_012497351.1 NC_011004:4893575-4893832 [Rhodopseudomonas palustris TIE-1]
MAERSWSVQDAKNRFSEVVEAARRSPQTVTKHGKPAVVVVDVAEYQRLQQLERATAPSFADVLLAMPRDDGDFSRDPVRM
RDVEL

Download         Length: 258 bp

>AT22967 NC_011004:4893575-4893832 [Rhodopseudomonas palustris TIE-1]
ATGGCCGAGCGCAGTTGGTCGGTGCAGGACGCCAAGAACCGGTTCAGCGAGGTCGTCGAGGCCGCGCGGCGCAGCCCGCA
GACGGTGACCAAGCACGGCAAGCCGGCCGTCGTCGTGGTCGACGTCGCCGAGTACCAACGACTCCAGCAACTCGAGCGCG
CCACCGCCCCGTCATTCGCCGATGTGCTGTTGGCAATGCCGCGGGACGACGGCGACTTTTCGCGTGATCCCGTGCGGATG
CGCGACGTCGAGCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBB3QJT1

Antitoxin

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Source
ID
Structure
AlphaFold DBB3QJT0

References