Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/Tad-HTH_37
Location 4676145..4676859 Replicon chromosome
Accession NC_011004
Organism Rhodopseudomonas palustris TIE-1

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag RPAL_RS21530 Protein ID WP_012497200.1
Coordinates 4676476..4676859 (-) Length 128 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID B3QI46
Locus tag RPAL_RS21525 Protein ID WP_012497199.1
Coordinates 4676145..4676495 (-) Length 117 a.a.

Genomic Context

RPAL_RS21515RPAL_RS21520RPAL_RS21545RPAL_RS21495RPAL_RS21500RPAL_RS21505RPAL_RS21510RPAL_RS21525RPAL_RS21530RPAL_RS21535RPAL_RS21540RPAL_RS21555RPAL_RS21560
Location: 4674222..4674545 (324 bp)
Type: Others
Protein ID: WP_012497197.1
Location: 4675117..4675791 (675 bp)
Type: Others
Protein ID: WP_012497198.1
Location: 4678782..4679021 (240 bp)
Type: Others
Protein ID: WP_012497203.1
Location: 4671707..4672408 (702 bp)
Type: Others
Protein ID: WP_012497195.1
Location: 4672465..4672704 (240 bp)
Type: Others
Protein ID: WP_011159357.1
Location: 4672728..4672973 (246 bp)
Type: Others
Protein ID: WP_011159358.1
Location: 4673156..4673923 (768 bp)
Type: Others
Protein ID: WP_011159359.1
Location: 4676145..4676495 (351 bp)
Type: Antitoxin
Protein ID: WP_012497199.1
Location: 4676476..4676859 (384 bp)
Type: Toxin
Protein ID: WP_012497200.1
Location: 4676968..4677786 (819 bp)
Type: Others
Protein ID: WP_012497201.1
Location: 4678103..4678486 (384 bp)
Type: Others
Protein ID: WP_012497202.1
Location: 4680442..4680996 (555 bp)
Type: Others
Protein ID: WP_012497205.1
Location: 4681067..4681549 (483 bp)
Type: Others
Protein ID: WP_012497206.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
RPAL_RS214954671707..4672408-702WP_012497195.1phosphoribosylformylglycinamidine synthase subunit PurQ-
RPAL_RS215004672465..4672704-240WP_011159357.1hypothetical protein-
RPAL_RS215054672728..4672973-246WP_011159358.1phosphoribosylformylglycinamidine synthase subunit PurS-
RPAL_RS215104673156..4673923-768WP_011159359.1phosphoribosylaminoimidazolesuccinocarboxamide synthase-
RPAL_RS215154674222..4674545+324WP_012497197.1DUF1476 domain-containing protein-
RPAL_RS215204675117..4675791+675WP_012497198.1hypothetical protein-
RPAL_RS215254676145..4676495-351WP_012497199.1helix-turn-helix domain-containing proteinAntitoxin
RPAL_RS215304676476..4676859-384WP_012497200.1type II toxin-antitoxin system RelE/ParE family toxinToxin
RPAL_RS215354676968..4677786-819WP_012497201.1isocitrate lyase/phosphoenolpyruvate mutase family protein-
RPAL_RS215404678103..4678486-384WP_012497202.1hypothetical protein-
RPAL_RS215454678782..4679021+240WP_012497203.1hypothetical protein-
RPAL_RS215554680442..4680996-555WP_012497205.1hypothetical protein-
RPAL_RS215604681067..4681549-483WP_012497206.1transcription elongation factor GreA-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(20-112)

Antitoxin

HigA2-like, helix-turn-helix domain

(21-100)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14384.36 Da        Isoelectric Point: 10.1303

>T22966 WP_012497200.1 NC_011004:c4676859-4676476 [Rhodopseudomonas palustris TIE-1]
MRPRLVSGEKPLHWVGSSKDDLCAFPLPVQREIGNALGLAQFGGKHPRAKPWKGEGPGVFEMVDDFDGDTYRAVYTVRFR
HAVYVLHAFQKKSPRGIRTARGDIELIARRLKLARQDDEARDGENDR

Download         Length: 384 bp

>T22966 NC_011004:c4676859-4676476 [Rhodopseudomonas palustris TIE-1]
ATGCGACCGCGACTTGTAAGCGGCGAAAAGCCGCTCCACTGGGTGGGCTCATCGAAAGACGACCTTTGCGCCTTTCCGTT
GCCGGTGCAGCGTGAGATCGGCAATGCGCTGGGATTGGCGCAGTTCGGCGGCAAGCATCCGCGTGCCAAGCCCTGGAAGG
GCGAGGGGCCGGGTGTGTTCGAAATGGTCGACGATTTCGACGGCGATACCTACCGCGCGGTCTATACGGTGCGCTTCCGG
CACGCGGTCTACGTGCTGCACGCATTCCAGAAGAAGTCGCCGCGCGGCATCCGAACCGCGCGCGGCGATATCGAACTCAT
TGCGCGGCGGCTGAAGCTCGCCCGACAGGACGACGAGGCTCGTGATGGCGAGAACGACCGCTAG

Antitoxin


Download         Length: 117 a.a.        Molecular weight: 12564.57 Da        Isoelectric Point: 11.2526

>AT22966 WP_012497199.1 NC_011004:c4676495-4676145 [Rhodopseudomonas palustris TIE-1]
MARTTASKGTAAEITRGSGNVFADLGMPDAEERQTKLRLAYALNVVIDRARLSQAAAAARLGINQPKVSALRNYKLEGFS
VERLMTLLNALDQDIEIIIRKKPRSRAAARISVVAA

Download         Length: 351 bp

>AT22966 NC_011004:c4676495-4676145 [Rhodopseudomonas palustris TIE-1]
ATGGCGAGAACGACCGCTAGCAAAGGCACGGCAGCCGAGATCACCCGCGGCAGCGGCAATGTGTTTGCGGACCTGGGCAT
GCCCGATGCGGAGGAGAGGCAGACCAAGCTCAGGCTCGCCTACGCTTTGAACGTGGTGATCGACCGCGCTCGCCTGAGCC
AAGCCGCCGCTGCCGCGCGGCTCGGGATCAACCAGCCCAAGGTTTCGGCCCTGCGCAACTACAAACTGGAAGGCTTTTCG
GTCGAGCGGCTGATGACGTTGCTCAACGCGCTCGATCAGGACATCGAAATTATCATCCGCAAAAAGCCACGCTCGCGCGC
GGCGGCGCGGATCAGCGTAGTGGCGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBB3QI46

References