Detailed information of TA system TA022965

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ataRT/DUF1778(antitoxin)
• Location: 4399957..4400813
• Replicon: chromosome
• Accession: NC_011004
• Organism: Rhodopseudomonas palustris TIE-1

Toxin (Protein)

• Gene name: ataT
• Uniprot ID: B3QFT4
• Locus tag: RPAL_RS20295
• Protein ID: WP_012497009.1
• Coordinates: 4399957..4400487 (-)
• Length: 177 a.a.

Antitoxin (Protein)

• Gene name: ataR
• Uniprot ID: B3QFT5
• Locus tag: RPAL_RS20300
• Protein ID: WP_012497010.1
• Coordinates: 4400475..4400813 (-)
• Length: 113 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RPAL_RS20275	4396622..4397551	+	930	WP_012497005.1	hypothetical protein	-
RPAL_RS20280	4397801..4398862	+	1062	WP_041810001.1	DUF4917 family protein	-
RPAL_RS20285	4399015..4399413	-	399	WP_012497007.1	ester cyclase	-
RPAL_RS20290	4399603..4399836	-	234	WP_012497008.1	hypothetical protein	-
RPAL_RS20295	4399957..4400487	-	531	WP_012497009.1	GNAT family N-acetyltransferase	Toxin
RPAL_RS20300	4400475..4400813	-	339	WP_012497010.1	DUF1778 domain-containing protein	Antitoxin
RPAL_RS20305	4400991..4401770	+	780	WP_012497011.1	hypothetical protein	-
RPAL_RS20310	4401952..4402464	-	513	WP_012497012.1	hypothetical protein	-
RPAL_RS20315	4402774..4403238	-	465	WP_012497013.1	hypothetical protein	-
RPAL_RS20320	4404448..4404732	+	285	WP_012497014.1	hypothetical protein	-
RPAL_RS20325	4404894..4405082	+	189	WP_012497015.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (51-151)

Antitoxin

• Vibrio phage ICP1, Orf50 (31-107)

Sequences

Toxin

Protein

• Length: 177 a.a.
• Molecular weight: 19151.86 Da
• Isoelectric Point: 7.2662

>T22965 WP_012497009.1 NC_011004:c4400487-4399957 [Rhodopseudomonas palustris TIE-1]
MADIDDAPNQPRSRLSAPVPLTMEHDLSAFDCGEPVLNDWLRQRALKNESRFSRTYVVCEGHQVVGYFCVSAGAIERAAA
PGKVRRNAPDTIRVSVIGRLAVSRSHAGIGLGADLLSDALRRIALASQSIGIGAVLVHAKDDAAKRFYLRCAEFIEYPED
SRTLFLPIETVVAAFS

Nucleotide

• Length: 531 bp

>T22965 NC_011004:c4400487-4399957 [Rhodopseudomonas palustris TIE-1]
ATGGCGGACATAGACGACGCGCCAAACCAGCCACGTTCCCGTCTGTCGGCTCCCGTTCCTCTGACGATGGAACATGATTT
GTCGGCGTTCGATTGCGGCGAACCGGTGTTGAACGACTGGCTGCGCCAACGGGCACTCAAGAACGAAAGCCGCTTCTCGC
GCACCTATGTGGTGTGCGAGGGCCACCAGGTCGTCGGCTATTTCTGCGTTTCAGCAGGCGCGATCGAGCGCGCGGCAGCG
CCGGGCAAGGTCCGCCGCAACGCGCCCGACACGATCCGGGTGTCGGTCATCGGACGACTGGCCGTCAGCCGCTCCCATGC
CGGAATAGGTCTCGGCGCCGACCTGCTTTCGGACGCGCTACGCCGGATCGCGCTGGCGTCGCAGAGCATCGGCATCGGCG
CGGTTCTGGTTCACGCCAAGGACGATGCGGCCAAACGCTTCTATCTGCGCTGCGCCGAATTCATCGAGTATCCCGAAGAC
AGTCGGACGCTGTTCCTGCCGATCGAAACGGTGGTCGCGGCCTTTAGTTAG

Antitoxin

Protein

• Length: 113 a.a.
• Molecular weight: 12160.97 Da
• Isoelectric Point: 11.4488

>AT22965 WP_012497010.1 NC_011004:c4400813-4400475 [Rhodopseudomonas palustris TIE-1]
MAKARGAPAKSARRSSAAAARGATSDAKGSINLRIETGTRQLIDDAAAVLGKTRTEFMVESARRQAVDVLLDQRLFTLDP
ERYDAFMQALDNPPAPGPKLKALLRRVPAWRT

Nucleotide

• Length: 339 bp

>AT22965 NC_011004:c4400813-4400475 [Rhodopseudomonas palustris TIE-1]
ATGGCAAAAGCGCGTGGAGCACCTGCAAAATCTGCTCGTCGTTCCTCTGCGGCCGCAGCGCGCGGCGCGACGTCCGACGC
CAAGGGCAGCATCAATCTGCGGATCGAGACGGGCACCCGTCAGCTGATCGACGATGCGGCGGCGGTGCTGGGGAAGACGC
GCACGGAATTCATGGTGGAGAGCGCCCGGCGGCAGGCCGTCGATGTGCTGCTTGATCAGCGCTTATTCACGCTCGATCCC
GAACGCTATGATGCCTTCATGCAGGCGCTCGACAATCCACCTGCGCCGGGACCGAAGCTCAAGGCGTTGCTGCGTCGGGT
CCCGGCATGGCGGACATAG

Structures

Toxin

• AlphaFold DB: B3QFT4

Antitoxin

• AlphaFold DB: B3QFT5