Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1838243..1838383 Replicon chromosome
Accession NZ_CP089926
Organism Klebsiella pneumoniae strain KP111

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1838279..1838381 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1838243..1838383 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LVQ71_RS08895 1833373..1835433 + 2061 WP_004151449.1 oligopeptidase B -
LVQ71_RS08900 1835437..1836096 - 660 WP_002911407.1 exodeoxyribonuclease X -
LVQ71_RS08905 1836175..1836405 - 231 WP_048254886.1 DNA polymerase III subunit theta -
LVQ71_RS08910 1836518..1836892 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LVQ71_RS08915 1836896..1837765 + 870 WP_004891049.1 copper homeostasis membrane protein CopD -
LVQ71_RS08920 1837782..1838120 + 339 WP_016529031.1 YebY family protein -
- 1838243..1838383 - 141 - - Antitoxin
- 1838279..1838381 + 103 - - Toxin
LVQ71_RS08925 1838459..1839544 - 1086 WP_277710220.1 phage integrase Arm DNA-binding domain-containing protein -
LVQ71_RS08930 1839513..1839785 - 273 WP_116961240.1 excisionase -
LVQ71_RS08935 1839902..1840168 - 267 WP_128619778.1 hypothetical protein -
LVQ71_RS08940 1840187..1840444 - 258 WP_116961252.1 DNA polymerase III subunit theta -
LVQ71_RS08945 1840489..1840815 - 327 WP_277710221.1 DUF2591 family protein -
LVQ71_RS08950 1840812..1840979 - 168 WP_277710222.1 DUF2737 family protein -
LVQ71_RS08955 1841324..1841806 - 483 WP_049001950.1 siphovirus Gp157 family protein -
LVQ71_RS08960 1841799..1842692 - 894 WP_277710225.1 RecT family recombinase -
LVQ71_RS08965 1842689..1842997 - 309 WP_253889961.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1833406..1900437 67031


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T229634 NZ_CP089926:1838279-1838381 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 141 bp

>AT229634 NZ_CP089926:c1838383-1838243 [Klebsiella pneumoniae]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References