Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) slvAT/RES(toxin)
Location 293739..294631 Replicon chromosome
Accession NZ_CP089924
Organism Lysobacter sp. 5GHs7-4

Toxin (Protein)


Gene name slvT Uniprot ID -
Locus tag LVB77_RS01200 Protein ID WP_232908406.1
Coordinates 293739..294221 (-) Length 161 a.a.

Antitoxin (Protein)


Gene name slvA Uniprot ID -
Locus tag LVB77_RS01205 Protein ID WP_232908407.1
Coordinates 294260..294631 (-) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LVB77_RS01185 (LVB77_01185) 289271..290521 + 1251 WP_232908403.1 FAD-binding oxidoreductase -
LVB77_RS01190 (LVB77_01190) 290808..292538 + 1731 WP_232908404.1 bifunctional isocitrate dehydrogenase kinase/phosphatase -
LVB77_RS01195 (LVB77_01195) 292556..293677 - 1122 WP_232908405.1 hypothetical protein -
LVB77_RS01200 (LVB77_01200) 293739..294221 - 483 WP_232908406.1 RES domain-containing protein Toxin
LVB77_RS01205 (LVB77_01205) 294260..294631 - 372 WP_232908407.1 DNA-binding protein Antitoxin
LVB77_RS01210 (LVB77_01210) 294771..294953 - 183 WP_232908408.1 hypothetical protein -
LVB77_RS01215 (LVB77_01215) 295082..296029 + 948 WP_232908409.1 LysR substrate-binding domain-containing protein -
LVB77_RS01220 (LVB77_01220) 296109..296972 + 864 WP_232908410.1 methyltransferase -
LVB77_RS01225 (LVB77_01225) 297086..297619 + 534 WP_232910412.1 pseudouridine synthase -
LVB77_RS01230 (LVB77_01230) 297840..298793 - 954 WP_232908411.1 DMT family transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(2-153)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 161 a.a.        Molecular weight: 17688.05 Da        Isoelectric Point: 4.9431

>T229630 WP_232908406.1 NZ_CP089924:c294221-293739 [Lysobacter sp. 5GHs7-4]
MHTPRWSFQPLSGAGAAISGGRLNRPGIDALYLALEPETAVEEFRQDDPLVRPGTLVAYRATIARVADFRAGYDPAHWPP
LWQELSCNWKRMAFLDEIEPPSWVIADDARAAGLAAIAFPSTRRAGGSNLVVYPDLLGADDRLLVHDPRMDLPIDPSSWR

Download         Length: 483 bp

>T229630 NZ_CP124500:2188581-2188683 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 13398.14 Da        Isoelectric Point: 6.7262

>AT229630 WP_232908407.1 NZ_CP089924:c294631-294260 [Lysobacter sp. 5GHs7-4]
VSAAAFDTFLETLREPSRPTLSPVRMAQALHMGVSDLAGLARVHRNTVTGNPESSQLQGALRDIVKVLAAAYRVNDDRER
TLFWFINHPIAEFGYQTAADLVRDGKSEAVIRYLATLEGGATG

Download         Length: 372 bp

>AT229630 NZ_CP124500:c2188721-2188453 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References