229628

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) itaRT/DUF1778(antitoxin)
Location 509012..509840 Replicon plasmid unnamed1
Accession NZ_CP089920
Organism Rahnella victoriana strain JZ-GX1

Toxin (Protein)


Gene name itaT Uniprot ID -
Locus tag J9880_RS23650 Protein ID WP_131693572.1
Coordinates 509304..509840 (+) Length 179 a.a.

Antitoxin (Protein)


Gene name itaR Uniprot ID -
Locus tag J9880_RS23645 Protein ID WP_232770581.1
Coordinates 509012..509323 (+) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J9880_RS23625 (J9880_23625) 505347..506363 + 1017 WP_232770918.1 ABC transporter permease -
J9880_RS23630 (J9880_23630) 506360..507265 + 906 WP_095925468.1 ABC transporter permease -
J9880_RS23635 (J9880_23635) 507237..508103 + 867 WP_095925840.1 ABC transporter ATP-binding protein -
J9880_RS23640 (J9880_23640) 508128..508898 + 771 WP_232770919.1 ABC transporter ATP-binding protein -
J9880_RS23645 (J9880_23645) 509012..509323 + 312 WP_232770581.1 DUF1778 domain-containing protein Antitoxin
J9880_RS23650 (J9880_23650) 509304..509840 + 537 WP_131693572.1 GNAT family N-acetyltransferase Toxin
J9880_RS23655 (J9880_23655) 509873..510808 - 936 WP_232770582.1 DMT family transporter -
J9880_RS23660 (J9880_23660) 510795..512609 - 1815 WP_232770583.1 ABC transporter permease subunit -
J9880_RS23665 (J9880_23665) 512609..514117 - 1509 WP_232770584.1 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid oqxB / blaRAHN-2 vipA/tssB / vipB/tssC / vasE/tssK / hcp/tssD / clpV/tssH / vgrG/tssI / tli1 / KPHS_23120 / tssF / hcp1 / AHA_1832 / AHA_1833 / clpB 1..722843 722843


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(79-154)

Antitoxin

Vibrio phage ICP1, Orf50

(19-96)


Sequences

Toxin        


Download         Length: 179 a.a.        Molecular weight: 19060.31 Da        Isoelectric Point: 9.1356

>T229628 WP_131693572.1 NZ_CP089920:509304-509840 [Rahnella victoriana]
MVNLQSKATGVMVCRYQADITYPGNKHFDCGNPVLNAFVRNSLKKSVRDGNCAAKALIDAQTGELFGVCTFSAYWLERGK
LAGAVSGSLPLEVGVVRLIMLGVATKVQNRGYGQDLLLAFFEQIKIIHAALPVKGVYLDAAPAAVNFYVRLGFVQLDAPA
NAFGAVPMFLGIQHILAA

Download         Length: 537 bp

>T229628 NZ_CP124500:1923552-1923806 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAAATTATCAAAGATACACGCAGAACACCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GCTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11373.05 Da        Isoelectric Point: 8.7454

>AT229628 WP_232770581.1 NZ_CP089920:509012-509323 [Rahnella victoriana]
MMPKVEVFPSDARNIKSARVELKTSPDLKEMLREAAAAAGLDLSAFILNAAIERAESVLDNQRRRELTAQGWQQINQLIS
EPAAPTLALQGLMRRKKDGQSAE

Download         Length: 312 bp

>AT229628 NZ_CP124500:1923304-1923555 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References