Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3448552..3449204 Replicon chromosome
Accession NZ_CP089919
Organism Rahnella victoriana strain JZ-GX1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag J9880_RS15870 Protein ID WP_095922438.1
Coordinates 3448552..3448971 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag J9880_RS15875 Protein ID WP_095922437.1
Coordinates 3448971..3449204 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J9880_RS15850 (J9880_15850) 3444464..3445600 - 1137 WP_232769582.1 hypothetical protein -
J9880_RS15860 (J9880_15860) 3445952..3447160 - 1209 WP_095922440.1 pyridoxal phosphate-dependent aminotransferase -
J9880_RS15865 (J9880_15865) 3447364..3448566 + 1203 WP_232769583.1 gamma-glutamyl-gamma-aminobutyrate hydrolase family protein -
J9880_RS15870 (J9880_15870) 3448552..3448971 - 420 WP_095922438.1 PIN domain-containing protein Toxin
J9880_RS15875 (J9880_15875) 3448971..3449204 - 234 WP_095922437.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
J9880_RS15880 (J9880_15880) 3449414..3450334 - 921 WP_095922436.1 dihydrodipicolinate synthase family protein -
J9880_RS15885 (J9880_15885) 3450369..3451553 - 1185 WP_095922435.1 Xaa-Pro peptidase family protein -
J9880_RS15890 (J9880_15890) 3451550..3452647 - 1098 WP_232769584.1 mandelate racemase/muconate lactonizing enzyme family protein -
J9880_RS15895 (J9880_15895) 3452658..3453821 - 1164 WP_095922433.1 M20 family metallopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-125)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15471.11 Da        Isoelectric Point: 7.9597

>T229625 WP_095922438.1 NZ_CP089919:c3448971-3448552 [Rahnella victoriana]
MLTYLLDTNIVIYILKRRPMSVLAKFNQHTDQLAISMITYAELLHGIAKSASPVKNKLAVEEFVSHLRIIDYDQKAAAHY
GHIRACLEKCGNLIGVNDMHIAAQARSAGMVMVTNNLHEFARVDGLLTENWVGPILTAL

Download         Length: 420 bp

>T229625 NZ_CP124500:c890616-890239 [Escherichia coli]
ATGAAAACATTACCCGACACACACGTACGGGCGGCATCGCGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCAACTGCTGGACCAGCACTATGGCCTCACGCTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGGATTTCACTGTGTGACGCGGTGAACTTTCTCGTTGAAAAATACGCGCTGGTACGTACCGACCAGCCGGGATTC
AGCGCAGGAGCCCCGTCGCAGTTAATCAACAGCATTGATATTCTCCGGGCTCGCAGGGCGACCGGCCTGATGACCCGGAA
CAATTACAAAATGGTAAATAACATTACCCAGGGCAAGCATCCGGAGGCAAAACGATGA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8767.78 Da        Isoelectric Point: 4.6750

>AT229625 WP_095922437.1 NZ_CP089919:c3449204-3448971 [Rahnella victoriana]
MPKGTVFLNNRTQSVRIPAECRFPDEVKIVTIRKVGNSLVLTPADNSWDNFFGSELRVTDDFMADRASQDQSDRDTF

Download         Length: 234 bp

>AT229625 NZ_CP124500:c891073-890693 [Escherichia coli]
ATGTCGGACACACTCCCCGGAACAACGCTTCCCGACGACAACAAAGACCGCCCCTGGTGGGGACTGCCCTGCACCGTGAC
GCCCTGTTTCGGCGCCCGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCAGACCGCGCCGGTATCAGGGGCCGGT
TCAACAATGCGGATGCATACCATCTGGACCAGGCTTTTCCACTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCGAAAGGGCTGACCTGCGATGCCGACACCCTCGGGTCCTG
TGGTTACGTTTATCTGGCTGTTTATCCTGCGACCGAAACGGAAAGTAACCCTCCGGAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References