Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 3221828..3222708 Replicon chromosome
Accession NZ_CP089919
Organism Rahnella victoriana strain JZ-GX1

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag J9880_RS14910 Protein ID WP_095922707.1
Coordinates 3221828..3222286 (-) Length 153 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag J9880_RS14915 Protein ID WP_232770477.1
Coordinates 3222283..3222708 (-) Length 142 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J9880_RS14885 (J9880_14885) 3217418..3219103 + 1686 WP_232769536.1 choline dehydrogenase -
J9880_RS14890 (J9880_14890) 3219194..3219652 + 459 WP_095922711.1 GNAT family N-acetyltransferase -
J9880_RS14895 (J9880_14895) 3219879..3220811 - 933 WP_095922710.1 LysR family transcriptional regulator -
J9880_RS14900 (J9880_14900) 3220912..3221346 + 435 WP_095922709.1 DMT family transporter -
J9880_RS14905 (J9880_14905) 3221350..3221802 + 453 WP_095922708.1 DMT family transporter -
J9880_RS14910 (J9880_14910) 3221828..3222286 - 459 WP_095922707.1 RES family NAD+ phosphorylase Toxin
J9880_RS14915 (J9880_14915) 3222283..3222708 - 426 WP_232770477.1 DUF2384 domain-containing protein Antitoxin
J9880_RS14920 (J9880_14920) 3223093..3223980 + 888 WP_013574724.1 nucleoside-specific channel-forming protein Tsx -
J9880_RS14925 (J9880_14925) 3224165..3225760 + 1596 WP_095922705.1 ABC-F family ATPase -
J9880_RS14930 (J9880_14930) 3225957..3226715 - 759 WP_232769537.1 molybdopterin-synthase adenylyltransferase MoeB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(2-141)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(87-138)


Sequences

Toxin        


Download         Length: 153 a.a.        Molecular weight: 16870.44 Da        Isoelectric Point: 5.6032

>T229624 WP_095922707.1 NZ_CP089919:c3222286-3221828 [Rahnella victoriana]
MKLFRIIQTQHLATAWSGAGAQLYGGRWNPPGRPVVYTTTSISLAILEILVHLQNSMLMRSYTLLSIDVPEALLDTLEVS
ELAADWRSPSPPDSTQRQGETWLVEGSYVGLKVPSVIVPAEYNVLLNPQHPAFAALLSSVQREPMMFDPRLQ

Download         Length: 459 bp

>T229624 NZ_CP124500:710608-710922 [Escherichia coli]
ATGCACCTGATAACTCAAAAAGCATTGAAAGATGCTGCGGAAAAATACCCGCAACATAAAACGGAGTTGGTGGCTCTGGG
GAACACGATTGCTAAGGGATATTTCAAAAAACCTGAGTCATTAAAAGCAGTATTCCCTTCTCTGGATAACTTCAAATATC
TGGATAAGCATTATGTTTTCAATGTCGGGGGCAATGAATTACGTGTTGTAGCAATGGTCTTTTTTGAATCGCAAAAGTGC
TACATACGTGAAGTTATGACGCATAAAGAATACGATTTCTTTACCGCCGTTCATCGTACTAAGGGGAAAAAATGA

Antitoxin


Download         Length: 142 a.a.        Molecular weight: 15454.79 Da        Isoelectric Point: 7.2062

>AT229624 WP_232770477.1 NZ_CP089919:c3222708-3222283 [Rahnella victoriana]
MQHPVTPLWQTAGLPASSGISLINAIQKGFPVDSINRLNTELGWPKMVLLEIMGINERNYARRKAGNGLLKSDESERVAR
LVRVIDAATDLFEGDRVSALDWITRPAPALDGSRPLELLMSEAGAVEVNRLIGRLQHGVFS

Download         Length: 426 bp

>AT229624 NZ_CP124500:710919-711335 [Escherichia coli]
ATGATTGCGATTGCCGACATCTTGCAAGCAGGAGAAAAGCTAACTGCTGTGGCACCTTTTCTGGCGGGTATTCAGAACGA
GGAACAATACACCCAGGCGCTGGAACTGGTAGATCATCTGCTGCTCAACGATCCTGAAAACCCCTTACTGGATCTGGTGT
GTGCCAAAATAACCGCGTGGGAAGAATCAGCGCCCGAATTTGTGGAATTTAATGCCATGGCTCAAGCCATGCCTGGCGGT
ATAGCCGTGATTCGTACCCTTATGGATCAATATGGTTTAACCCTTTCCGATCTTCCGGAAATAGGCAGTAAATCGATGGT
GTCACGCGTTTTGAGCGGGAAAAGGAAATTAACGCTGGAACACGCTAAAAAACTGGCAACGCGATTCGGTATTTCTCCCG
CCTTGTTTATTGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References