Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 475275..475892 Replicon chromosome
Accession NZ_CP089919
Organism Rahnella victoriana strain JZ-GX1

Toxin (Protein)


Gene name Hha Uniprot ID -
Locus tag J9880_RS02395 Protein ID WP_056771138.1
Coordinates 475689..475892 (+) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID -
Locus tag J9880_RS02390 Protein ID WP_232770034.1
Coordinates 475275..475643 (+) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J9880_RS02360 (J9880_02360) 471281..471535 + 255 WP_095924977.1 type B 50S ribosomal protein L31 -
J9880_RS02365 (J9880_02365) 471556..471696 + 141 WP_119826771.1 type B 50S ribosomal protein L36 -
J9880_RS02370 (J9880_02370) 471819..472697 - 879 WP_232770032.1 metal ABC transporter substrate-binding protein -
J9880_RS02375 (J9880_02375) 472741..473598 - 858 WP_095924974.1 metal ABC transporter permease -
J9880_RS02380 (J9880_02380) 473595..474323 - 729 WP_232770033.1 ABC transporter ATP-binding protein -
J9880_RS02385 (J9880_02385) 474689..475042 + 354 WP_119826777.1 hypothetical protein -
J9880_RS02390 (J9880_02390) 475275..475643 + 369 WP_232770034.1 Hha toxicity modulator TomB Antitoxin
J9880_RS02395 (J9880_02395) 475689..475892 + 204 WP_056771138.1 HHA domain-containing protein Toxin
J9880_RS02400 (J9880_02400) 475985..476926 - 942 WP_232770433.1 LysR family transcriptional regulator -
J9880_RS02405 (J9880_02405) 477064..478851 + 1788 WP_095924969.1 adenine deaminase C-terminal domain-containing protein -
J9880_RS02410 (J9880_02410) 478928..480277 + 1350 WP_095924968.1 NCS2 family permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-118)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8098.45 Da        Isoelectric Point: 6.9764

>T229620 WP_056771138.1 NZ_CP089919:475689-475892 [Rahnella victoriana]
MNKIDYLMRLRKCTTIDTLERVIEKNKYELSDDELELFYSAADHRLAELTMNKLYDKIPVAVWKFVR

Download         Length: 204 bp

>T229620 NZ_CP124500:256091-256198 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14422.17 Da        Isoelectric Point: 5.1592

>AT229620 WP_232770034.1 NZ_CP089919:475275-475643 [Rahnella victoriana]
MDEYSPKRHDIAQLRYLNEMLYDEGIATLGDSHHGWVNDPTSAVNLQLNELIEHIASFVMSFKIKHPDDNHLTDRVEEYL
DDTYTLFSNYGINDSDLRQWQKTKKRLFRMFSGDYICTLMKT

Download         Length: 369 bp

>AT229620 NZ_CP124500:c256042-255977 [Escherichia coli]
GTCTAGATGCAAGAATGGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References