Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2389632..2390302 Replicon chromosome
Accession NC_011004
Organism Rhodopseudomonas palustris TIE-1

Toxin (Protein)


Gene name vapC Uniprot ID Q6N8B2
Locus tag RPAL_RS10950 Protein ID WP_011157547.1
Coordinates 2389632..2390042 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag RPAL_RS26805 Protein ID WP_011157548.1
Coordinates 2390039..2390302 (-) Length 88 a.a.

Genomic Context

RPAL_RS27340RPAL_RS10940RPAL_RS10945RPAL_RS10955RPAL_RS10970RPAL_RS10950RPAL_RS26805RPAL_RS10960RPAL_RS10965
Location: 2386009..2386335 (327 bp)
Type: Others
Protein ID: WP_150104521.1
Location: 2386502..2388292 (1791 bp)
Type: Others
Protein ID: WP_012495518.1
Location: 2388304..2389377 (1074 bp)
Type: Others
Protein ID: WP_150104522.1
Location: 2390483..2390908 (426 bp)
Type: Others
Protein ID: WP_012495520.1
Location: 2393070..2394545 (1476 bp)
Type: Others
Protein ID: WP_012495522.1
Location: 2389632..2390042 (411 bp)
Type: Toxin
Protein ID: WP_011157547.1
Location: 2390039..2390302 (264 bp)
Type: Antitoxin
Protein ID: WP_011157548.1
Location: 2391005..2392174 (1170 bp)
Type: Others
Protein ID: WP_012495521.1
Location: 2392360..2392668 (309 bp)
Type: Others
Protein ID: WP_011157551.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
RPAL_RS273402386009..2386335+327WP_150104521.1hypothetical protein-
RPAL_RS109402386502..2388292+1791WP_012495518.1sulfatase-like hydrolase/transferase-
RPAL_RS109452388304..2389377+1074WP_150104522.1transporter-
RPAL_RS109502389632..2390042-411WP_011157547.1type II toxin-antitoxin system VapC family toxinToxin
RPAL_RS268052390039..2390302-264WP_011157548.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
RPAL_RS109552390483..2390908+426WP_012495520.1cupin domain-containing protein-
RPAL_RS109602391005..2392174-1170WP_012495521.1DUF2865 domain-containing protein-
RPAL_RS109652392360..2392668-309WP_011157551.1hypothetical protein-
RPAL_RS109702393070..2394545+1476WP_012495522.1cysteine--tRNA ligase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-124)

Antitoxin

SpoVT-AbrB domain

(9-58)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15136.48 Da        Isoelectric Point: 5.6802

>T22961 WP_011157547.1 NC_011004:c2390042-2389632 [Rhodopseudomonas palustris TIE-1]
MSGWMLDTNVASHVIRGDRREIIERLVALPISDVVISSITEGELLYGLAKRGYPTALSERVREFLLRVDVLPWDHEVTKT
YADLRAVCEAKGVTLSPLDMMIAAHAAATNATLVTRDKAFSRVPSPLRIEDWAEMS

Download         Length: 411 bp

>T22961 NC_011004:c2390042-2389632 [Rhodopseudomonas palustris TIE-1]
ATGAGTGGCTGGATGCTCGATACCAACGTCGCCAGCCATGTCATCAGGGGCGACCGGCGCGAGATCATCGAGCGGCTAGT
CGCTTTGCCGATCTCGGACGTCGTCATCTCATCGATCACAGAAGGTGAACTCCTCTACGGCCTGGCTAAGCGCGGCTATC
CCACCGCGTTATCCGAACGCGTCCGAGAATTTCTACTCCGCGTCGACGTCCTACCGTGGGATCACGAGGTGACGAAGACT
TACGCCGACCTGCGCGCAGTCTGCGAAGCCAAAGGCGTCACACTCTCTCCTCTCGACATGATGATCGCTGCCCATGCCGC
TGCGACAAACGCAACGTTGGTCACGCGCGACAAGGCCTTCAGCCGCGTGCCTTCACCATTGCGGATCGAGGACTGGGCAG
AGATGAGTTGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9888.91 Da        Isoelectric Point: 4.7969

>AT22961 WP_011157548.1 NC_011004:c2390302-2390039 [Rhodopseudomonas palustris TIE-1]
VTSRTAKIFTTGRSQAVRLPAEFRFEGSEVFVRRDPRTGDVILSRKPDSWDGLLQLHQSADVPDDFLGPSDRSQLPQDRD
PFEGWTE

Download         Length: 264 bp

>AT22961 NC_011004:c2390302-2390039 [Rhodopseudomonas palustris TIE-1]
GTGACGTCTCGAACCGCCAAGATTTTCACAACTGGACGCAGCCAAGCTGTCCGACTGCCAGCGGAGTTTCGCTTCGAGGG
CAGCGAGGTGTTTGTACGCCGTGATCCGCGGACCGGCGATGTCATTCTGTCCCGAAAACCGGACTCCTGGGACGGCCTAC
TCCAGCTTCACCAGTCGGCGGATGTACCCGACGACTTCTTGGGACCGTCCGACCGTAGCCAGCTTCCGCAGGATCGCGAT
CCGTTCGAAGGCTGGACCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBQ6N8B2

Antitoxin

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Source
ID
Structure
No matching records found

References