Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1947789..1947934 Replicon chromosome
Accession NZ_CP089884
Organism Klebsiella pneumoniae strain KP102

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1947825..1947927 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1947789..1947934 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LR951_RS09520 (LR951_09505) 1942920..1944980 + 2061 WP_032430257.1 oligopeptidase B -
LR951_RS09525 (LR951_09510) 1944984..1945643 - 660 WP_002911407.1 exodeoxyribonuclease X -
LR951_RS09530 (LR951_09515) 1945722..1945952 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LR951_RS09535 (LR951_09520) 1946065..1946439 + 375 WP_016529032.1 CopC domain-containing protein YobA -
LR951_RS09540 (LR951_09525) 1946443..1947312 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
LR951_RS09545 (LR951_09530) 1947329..1947667 + 339 WP_002911404.1 YebY family protein -
- 1947789..1947934 - 146 - - Antitoxin
- 1947825..1947927 + 103 - - Toxin
LR951_RS09550 (LR951_09535) 1948302..1948445 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LR951_RS09555 (LR951_09540) 1948550..1949518 - 969 WP_004151446.1 VirK/YbjX family protein -
LR951_RS09560 (LR951_09545) 1949675..1950328 + 654 WP_021440384.1 protein-serine/threonine phosphatase -
LR951_RS09565 (LR951_09550) 1950325..1950516 - 192 WP_002911395.1 YebW family protein -
LR951_RS09570 (LR951_09555) 1950614..1950853 - 240 WP_002911393.1 YebV family protein -
LR951_RS09575 (LR951_09560) 1950969..1952402 - 1434 WP_023157970.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T229595 NZ_CP089884:1947825-1947927 [Klebsiella pneumoniae]
GCAAGGCGATTTTGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT229595 NZ_CP089884:c1947934-1947789 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCAAAATCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References