Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1898443..1898588 Replicon chromosome
Accession NZ_CP089882
Organism Klebsiella pneumoniae strain KP059

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1898479..1898581 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1898443..1898588 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LVQ69_RS09185 (LVQ69_09170) 1893573..1895633 + 2061 WP_004151449.1 oligopeptidase B -
LVQ69_RS09190 (LVQ69_09175) 1895637..1896296 - 660 WP_002911407.1 exodeoxyribonuclease X -
LVQ69_RS09195 (LVQ69_09180) 1896375..1896605 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LVQ69_RS09200 (LVQ69_09185) 1896718..1897092 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LVQ69_RS09205 (LVQ69_09190) 1897096..1897965 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
LVQ69_RS09210 (LVQ69_09195) 1897982..1898320 + 339 WP_002911404.1 YebY family protein -
- 1898443..1898588 - 146 - - Antitoxin
- 1898479..1898581 + 103 - - Toxin
LVQ69_RS09215 (LVQ69_09200) 1898956..1899099 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LVQ69_RS09220 (LVQ69_09205) 1899204..1900172 - 969 WP_004151446.1 VirK/YbjX family protein -
LVQ69_RS09225 (LVQ69_09210) 1900329..1900982 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LVQ69_RS09230 (LVQ69_09215) 1900979..1901170 - 192 WP_002911395.1 YebW family protein -
LVQ69_RS09235 (LVQ69_09220) 1901268..1901507 - 240 WP_002911393.1 YebV family protein -
LVQ69_RS09240 (LVQ69_09225) 1901623..1903056 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T229576 NZ_CP089882:1898479-1898581 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT229576 NZ_CP089882:c1898588-1898443 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References