Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 898328..898936 Replicon chromosome
Accession NC_011001
Organism Burkholderia cenocepacia J2315

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QU43_RS58465 Protein ID WP_006490978.1
Coordinates 898631..898936 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QU43_RS58460 Protein ID WP_006490972.1
Coordinates 898328..898627 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QU43_RS58435 893561..894832 + 1272 WP_006490988.1 Rieske 2Fe-2S domain-containing protein -
QU43_RS58440 894848..895324 + 477 WP_006490977.1 aromatic-ring-hydroxylating dioxygenase subunit beta -
QU43_RS58445 895360..895686 + 327 WP_006490973.1 non-heme iron oxygenase ferredoxin subunit -
QU43_RS58450 895676..896896 + 1221 WP_006490971.1 FAD-dependent oxidoreductase -
QU43_RS58455 896993..898279 + 1287 WP_006490986.1 DUF445 domain-containing protein -
QU43_RS58460 898328..898627 - 300 WP_006490972.1 putative addiction module antidote protein Antitoxin
QU43_RS58465 898631..898936 - 306 WP_006490978.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QU43_RS58470 899325..900965 + 1641 WP_006490980.1 acetolactate synthase large subunit -
QU43_RS58475 900994..902427 + 1434 WP_006490987.1 aldehyde dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(9-96)

Antitoxin

Uncharacterized protein HI1420

(4-96)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11270.88 Da        Isoelectric Point: 7.2764

>T22956 WP_006490978.1 NC_011001:c898936-898631 [Burkholderia cenocepacia J2315]
MPYSPPAFSIRTTDVFDAWFAGLPDRRIQARIDRLSMGNPGDWKSAGSPVVEMRIDHGPGYRVYDVRRGTIWVILLCGGD
KSAQQADIRAAHAMLAHLDME

Download         Length: 306 bp

>T22956 NC_011001:c898936-898631 [Burkholderia cenocepacia J2315]
ATGCCCTACAGTCCTCCTGCATTCAGCATCCGGACCACCGACGTCTTCGACGCCTGGTTTGCCGGCCTGCCCGATCGCCG
CATCCAGGCGCGCATCGACCGCCTGTCGATGGGCAATCCGGGCGACTGGAAATCCGCCGGCTCCCCCGTCGTCGAAATGC
GTATCGACCACGGCCCGGGCTATCGCGTCTATGACGTGAGGCGCGGAACGATATGGGTCATCCTGCTCTGCGGCGGCGAT
AAATCGGCGCAACAGGCCGACATCCGCGCCGCGCACGCAATGCTCGCGCACCTCGACATGGAGTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10608.04 Da        Isoelectric Point: 6.4771

>AT22956 WP_006490972.1 NC_011001:c898627-898328 [Burkholderia cenocepacia J2315]
MDKIKTRPWDSAEHLKTEDDMADYFDACLQEAGDDPAFIAHALGVIARARGMSQVARDAGLSREGLYKALSHDGNPSFGT
ILKVIKALGLQLHGAKAAA

Download         Length: 300 bp

>AT22956 NC_011001:c898627-898328 [Burkholderia cenocepacia J2315]
ATGGACAAGATCAAGACGCGGCCGTGGGATTCGGCCGAACACCTGAAAACCGAAGACGACATGGCCGACTACTTCGACGC
ATGCCTGCAGGAGGCCGGCGACGATCCGGCCTTCATCGCGCATGCGCTCGGCGTGATCGCCCGCGCACGCGGCATGTCGC
AGGTCGCACGCGATGCGGGCCTGTCGCGCGAAGGGCTGTACAAGGCGCTGTCGCACGACGGCAATCCGAGCTTCGGCACG
ATCCTGAAAGTCATCAAGGCGCTCGGCCTGCAATTGCACGGCGCCAAGGCTGCCGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References