Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1842223..1842368 Replicon chromosome
Accession NZ_CP089880
Organism Klebsiella pneumoniae strain KP309

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1842259..1842361 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1842223..1842368 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LVQ72_RS08915 (LVQ72_08910) 1837353..1839413 + 2061 WP_004151449.1 oligopeptidase B -
LVQ72_RS08920 (LVQ72_08915) 1839417..1840076 - 660 WP_002911407.1 exodeoxyribonuclease X -
LVQ72_RS08925 (LVQ72_08920) 1840155..1840385 - 231 WP_048254886.1 DNA polymerase III subunit theta -
LVQ72_RS08930 (LVQ72_08925) 1840498..1840872 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LVQ72_RS08935 (LVQ72_08930) 1840876..1841745 + 870 WP_004184661.1 copper homeostasis membrane protein CopD -
LVQ72_RS08940 (LVQ72_08935) 1841762..1842100 + 339 WP_002911404.1 YebY family protein -
- 1842223..1842368 - 146 - - Antitoxin
- 1842259..1842361 + 103 - - Toxin
LVQ72_RS08945 (LVQ72_08940) 1842736..1842879 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LVQ72_RS08950 (LVQ72_08945) 1842984..1843952 - 969 WP_014907334.1 VirK/YbjX family protein -
LVQ72_RS08955 (LVQ72_08950) 1844109..1844762 + 654 WP_048254884.1 protein-serine/threonine phosphatase -
LVQ72_RS08960 (LVQ72_08955) 1844759..1844950 - 192 WP_002911395.1 YebW family protein -
LVQ72_RS08965 (LVQ72_08960) 1845048..1845287 - 240 WP_002911393.1 YebV family protein -
LVQ72_RS08970 (LVQ72_08965) 1845403..1846836 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T229555 NZ_CP089880:1842259-1842361 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT229555 NZ_CP089880:c1842368-1842223 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References