Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1854439..1854584 Replicon chromosome
Accession NZ_CP089877
Organism Klebsiella pneumoniae strain KP308

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1854475..1854577 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1854439..1854584 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LVQ70_RS08935 (LVQ70_08925) 1849569..1851629 + 2061 WP_004151449.1 oligopeptidase B -
LVQ70_RS08940 (LVQ70_08930) 1851633..1852292 - 660 WP_002911407.1 exodeoxyribonuclease X -
LVQ70_RS08945 (LVQ70_08935) 1852371..1852601 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LVQ70_RS08950 (LVQ70_08940) 1852714..1853088 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LVQ70_RS08955 (LVQ70_08945) 1853092..1853961 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
LVQ70_RS08960 (LVQ70_08950) 1853978..1854316 + 339 WP_002911404.1 YebY family protein -
- 1854439..1854584 - 146 - - Antitoxin
- 1854475..1854577 + 103 - - Toxin
LVQ70_RS08965 (LVQ70_08955) 1854952..1855095 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LVQ70_RS08970 (LVQ70_08960) 1855200..1856168 - 969 WP_004151446.1 VirK/YbjX family protein -
LVQ70_RS08975 (LVQ70_08965) 1856325..1856978 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
LVQ70_RS08980 (LVQ70_08970) 1856975..1857166 - 192 WP_002911395.1 YebW family protein -
LVQ70_RS08985 (LVQ70_08975) 1857264..1857503 - 240 WP_002911393.1 YebV family protein -
LVQ70_RS08990 (LVQ70_08980) 1857619..1859052 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T229535 NZ_CP089877:1854475-1854577 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT229535 NZ_CP089877:c1854584-1854439 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References