Detailed information of TA system TA229480

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PanAT/DUF4065(antitoxin)
• Location: 296628..297583
• Replicon: chromosome
• Accession: NZ_CP089849
• Organism: Pseudomonas aeruginosa strain PA0523

Toxin (Protein)

• Gene name: panT
• Uniprot ID: -
• Locus tag: LVE67_RS01355
• Protein ID: WP_170868726.1
• Coordinates: 297257..297583 (+)
• Length: 109 a.a.

Antitoxin (Protein)

• Gene name: panA
• Uniprot ID: -
• Locus tag: LVE67_RS01350
• Protein ID: WP_023107584.1
• Coordinates: 296628..297185 (+)
• Length: 186 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LVE67_RS01325 (LVE67_01325)	291685..291972	-	288	WP_023443569.1	hypothetical protein	-
LVE67_RS01330 (LVE67_01330)	292064..292540	-	477	WP_009315008.1	MarR family transcriptional regulator	-
LVE67_RS01335 (LVE67_01335)	292581..294071	-	1491	WP_003111463.1	UbiD family decarboxylase HudA	-
LVE67_RS01340 (LVE67_01340)	294205..294891	-	687	WP_003106170.1	YoaK family protein	-
LVE67_RS01345 (LVE67_01345)	295055..295987	-	933	WP_023108709.1	hypothetical protein	-
LVE67_RS01350 (LVE67_01350)	296628..297185	+	558	WP_023107584.1	Panacea domain-containing protein	Antitoxin
LVE67_RS01355 (LVE67_01355)	297257..297583	+	327	WP_170868726.1	hypothetical protein	Toxin
LVE67_RS01365 (LVE67_01365)	299028..300470	-	1443	WP_003133043.1	DUF2875 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Antitoxin SocA-like, Panacea domain (28-138)

Sequences

Toxin

Protein

• Length: 109 a.a.
• Molecular weight: 12366.33 Da
• Isoelectric Point: 8.6957

>T229480 WP_170868726.1 NZ_CP089849:297257-297583 [Pseudomonas aeruginosa]
MNDPVYCPVLGYDAVLLVNISTVYPDKYFDQSCILKKGCHPFVLHDSWVVYREAGPFNLARLEQGVAQKSIKTHQPINAG
DFTRIRAGFDISPDVKIKVERFMRQHKI

Nucleotide

• Length: 327 bp

>T229480 NZ_CP089849:297257-297583 [Pseudomonas aeruginosa]
ATGAATGACCCCGTGTACTGCCCGGTTCTTGGGTATGACGCGGTGTTGCTTGTCAACATCTCGACTGTCTATCCAGATAA
GTATTTCGATCAGTCATGCATTCTAAAGAAGGGTTGTCATCCCTTTGTTCTGCACGACAGCTGGGTCGTATACCGCGAGG
CAGGCCCTTTCAACCTTGCACGGCTTGAGCAAGGGGTAGCGCAGAAGTCCATCAAGACGCATCAGCCCATCAACGCAGGC
GATTTCACTCGGATTCGGGCAGGCTTCGACATCTCGCCCGACGTCAAAATCAAAGTTGAGCGGTTCATGAGGCAGCACAA
GATTTAG

Antitoxin

Protein

• Length: 186 a.a.
• Molecular weight: 21377.14 Da
• Isoelectric Point: 5.8950

>AT229480 WP_023107584.1 NZ_CP089849:296628-297185 [Pseudomonas aeruginosa]
VIFSEQKVAHMAAFFLASAEGPLPHLTLIKLLYLADRESMARFDVPMSDDRAVSMPHGPVLSSTLDLIKGRLRSEVWSAW
ISPLVDHEVRLVHDVENWDDLDELSRSDRSILESVWQEFGHMTKYQLRDYTHHHIGEWHDPHGSSRDIDPKDTFMALGQS
EELAEIKARDLAERRRHGRKLSEFI

Nucleotide

• Length: 558 bp

>AT229480 NZ_CP089849:296628-297185 [Pseudomonas aeruginosa]
GTGATCTTCAGTGAACAGAAAGTGGCTCACATGGCAGCTTTCTTTTTGGCGAGTGCCGAAGGGCCGCTGCCTCATCTCAC
GCTGATCAAACTGCTGTACCTGGCAGACCGAGAGTCGATGGCTCGTTTCGACGTTCCCATGTCGGACGATCGAGCTGTTT
CCATGCCCCATGGGCCTGTCCTTTCCTCGACGCTAGACCTCATCAAGGGGCGTTTGCGCTCTGAGGTTTGGAGCGCTTGG
ATTTCTCCGTTGGTGGATCACGAGGTCCGTCTGGTCCATGACGTGGAGAATTGGGACGATCTGGATGAGTTGAGCCGATC
GGATCGCAGCATTTTGGAATCGGTCTGGCAAGAGTTTGGCCACATGACCAAGTACCAATTGCGGGACTACACCCACCATC
ACATTGGTGAGTGGCACGACCCCCACGGCTCTTCCAGGGACATTGATCCAAAGGATACTTTCATGGCGCTTGGTCAAAGC
GAGGAGCTGGCGGAGATCAAGGCGCGCGATCTTGCTGAGCGCCGTCGGCACGGTAGGAAGCTGTCTGAGTTCATTTGA